Search Results - "Alford, Brynn"

Single Particle Analysis of H3N2 Influenza Entry Differentiates the Impact of the Sialic Acids (Neu5Ac and Neu5Gc) on Virus Binding and Membrane Fusion by Chien, Yu-An Annie, Alford, Brynn K, Wasik, Brian R, Weichert, Wendy S, Parrish, Colin R, Daniel, Susan

“…Entry of influenza A viruses (IAVs) into host cells is initiated by binding to sialic acids (Sias), their primary host cell receptor, followed by endocytosis…”
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Modified Sialic Acids on Mucus and Erythrocytes Inhibit Influenza A Virus Hemagglutinin and Neuraminidase Functions by Barnard, Karen N, Alford-Lawrence, Brynn K, Buchholz, David W, Wasik, Brian R, LaClair, Justin R, Yu, Hai, Honce, Rebekah, Ruhl, Stefan, Pajic, Petar, Daugherity, Erin K, Chen, Xi, Schultz-Cherry, Stacey L, Aguilar, Hector C, Varki, Ajit, Parrish, Colin R

“…Sialic acids (Sia) are the primary receptors for influenza viruses and are widely displayed on cell surfaces and in secreted mucus. Sia may be present in…”
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Viral Capsid, Antibody, and Receptor Interactions: Experimental Analysis of the Antibody Escape Evolution of Canine Parvovirus by López-Astacio, Robert A, Adu, Oluwafemi F, Goetschius, Daniel J, Lee, Hyunwook, Weichert, Wendy S, Wasik, Brian R, Frueh, Simon P, Alford, Brynn K, Voorhees, Ian E H, Flint, Joseph F, Saddoris, Sarah, Goodman, Laura B, Holmes, Edward C, Hafenstein, Susan L, Parrish, Colin R

“…Canine parvovirus (CPV) is a small nonenveloped single-stranded DNA virus that causes serious diseases in dogs worldwide. The original strain of the virus…”
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Sequence dynamics of three influenza A virus strains grown in different MDCK cell lines, including those expressing different sialic acid receptors by Barnard, Karen N., Wasik, Brian R., Alford, Brynn K., Hayward, Jessica J., Weichert, Wendy S., Voorhees, Ian E. H., Holmes, Edward C., Parrish, Colin R.

“…Viruses are often cultured in cell lines for research and vaccine development, and those often differ from the natural hosts or tissues. Cell lines can also…”
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Influenza Viruses in Mice: Deep Sequencing Analysis of Serial Passage and Effects of Sialic Acid Structural Variation by Wasik, Brian R, Voorhees, Ian E H, Barnard, Karen N, Alford-Lawrence, Brynn K, Weichert, Wendy S, Hood, Grace, Nogales, Aitor, Martínez-Sobrido, Luis, Holmes, Edward C, Parrish, Colin R

“…Influenza A viruses have regularly jumped to new host species to cause epidemics or pandemics, an evolutionary process that involves variation in the viral…”
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Expression of 9- O - and 7,9- O -Acetyl Modified Sialic Acid in Cells and Their Effects on Influenza Viruses by Barnard, Karen N, Wasik, Brian R, LaClair, Justin R, Buchholz, David W, Weichert, Wendy S, Alford-Lawrence, Brynn K, Aguilar, Hector C, Parrish, Colin R

“…Sialic acids (Sia) are widely displayed on the surfaces of cells and tissues. Sia come in a variety of chemically modified forms, including those with acetyl…”
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Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization by Liu, Zhuoming, VanBlargan, Laura A., Bloyet, Louis-Marie, Rothlauf, Paul W., Chen, Rita E., Stumpf, Spencer, Zhao, Haiyan, Errico, John M., Theel, Elitza S., Liebeskind, Mariel J., Alford, Brynn, Buchser, William J., Ellebedy, Ali H., Fremont, Daved H., Diamond, Michael S., Whelan, Sean P.J.

“…Neutralizing antibodies against the SARS-CoV-2 spike (S) protein are a goal of COVID-19 vaccines and have received emergency use authorization as therapeutics…”
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Expression of 9- italic toggle="yes">O /italic>- and 7,9- italic toggle="yes">O /italic>-Acetyl Modified Sialic Acid in Cells and Their Effects on Influenza Viruses by Karen N. Barnard, Brian R. Wasik, Justin R. LaClair, David W. Buchholz, Wendy S. Weichert, Brynn K. Alford-Lawrence, Hector C. Aguilar, Colin R. Parrish

“…ABSTRACT Sialic acids (Sia) are widely displayed on the surfaces of cells and tissues. Sia come in a variety of chemically modified forms, including those with…”
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