Search Results - "Alfonzo, J D"

Identification of Leishmania selenoproteins and SECIS element by Cassago, A., Rodrigues, E.M., Prieto, E.L., Gaston, K.W., Alfonzo, J.D., Iribar, M.P., Berry, M.J., Cruz, A.K., Thiemann, O.H.

“…Selenoproteins result from the incorporation of selenocysteine (Sec-U) at an UGA-stop codon positioned within a gene's open reading frame and directed by…”
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C to U editing of the anticodon of imported mitochondrial tRNA(Trp) allows decoding of the UGA stop codon in Leishmania tarentolae by Alfonzo, J D, Blanc, V, Estévez, A M, Rubio, M A, Simpson, L

“…All mitochondrial tRNAs in kinetoplastid protists are encoded in the nucleus and imported into the organelle. The tRNA(Trp)(CCA) can decode the standard UGG…”
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Evolution of RNA Editing in Trypanosome Mitochondria by Simpson, Larry, Thiemann, Otavio H., Savill, Nicholas J., Alfonzo, Juan D., Maslov, D. A.

“…Two different RNA editing systems have been described in the kinetoplast-mitochondrion of trypanosomatid protists. The first involves the precise insertion and…”
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The mechanism of U insertion/deletion RNA editing in kinetoplastid mitochondria by Alfonzo, J D, Thiemann, O, Simpson, L

“…Recent advances in in vitrosystems and identification of putative enzymatic activities have led to the acceptance of a modified 'enzyme cascade' model for U…”
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Modification of the universally unmodified uridine-33 in a mitochondria-imported edited tRNA and the role of the anticodon arm structure on editing efficiency by CRAIN, PAMELA F., ALFONZO, JUAN D., ROZENSKI, JEF, KAPUSHOC, STEPHEN T., MCCLOSKEY, JAMES A., SIMPSON, LARRY

“…Editing of tRNA has a wide phylogenetic distribution among eukaryotes and in some cases serves to expand the decoding capacity of the target tRNA. We…”
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Selective importation of RNA into isolated mitochondria from Leishmania tarentolae by RUBIO, MARY ANNE T., LIU, XUAN, YUZAWA, HARUMI, ALFONZO, JUAN D., SIMPSON, LARRY

“…All mitochondrial tRNAs in kinetoplastid protozoa are encoded in the nucleus and imported from the cytosol. Incubation of two in vitro-transcribed tRNAs,…”
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Differential localization of nuclear-encoded tRNAs between the cytosol and mitochondrion in Leishmania tarentolae by KAPUSHOC, STEPHEN T., ALFONZO, JUAN D., SIMPSON, LARRY

“…All mitochondrial tRNAs of the kinetoplastid protozoan Leishmania tarentolae are encoded in the nucleus and are imported from the cytosol into the…”
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The Mitochondrial RNA Ligase from Leishmania tarentolae Can Join RNA Molecules Bridged by a Complementary RNA by Blanc, Valerie, Alfonzo, Juan D., Aphasizhev, Ruslan, Simpson, Larry

“…A biochemical characterization was performed with a partially purified RNA ligase from isolated mitochondria of Leishmania tarentolae. This ligase has a Km of…”
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End Processing Precedes Mitochondrial Importation and Editing of tRNAs in Leishmania tarentolae by Kapushoc, Stephen T., Alfonzo, Juan D., Rubio, Mary Anne T., Simpson, Larry

“…All mitochondrial tRNAs in Leishmania tarentolae are encoded in the nuclear genome and imported into the mitochondrion from the cytosol. One imported tRNA…”
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RBP38, a Novel RNA-Binding Protein from Trypanosomatid Mitochondria, Modulates RNA Stability by Sbicego, Sandro, Alfonzo, Juan D., Estévez, Antonio M., Rubio, Mary Anne T., Kang, Xuedong, Turck, Christoph W., Peris, Marian, Simpson, Larry

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Purification and characterization of MAR1. A mitochondrial associated ribonuclease from Leishmania tarentolae by Alfonzo, J D, Thiemann, O H, Simpson, L

“…A relatively thermostable 22-kDa endoribonuclease (MAR1) was purified more than 10,000-fold from a mitochondrial extract of Leishmania tarentolae and the gene…”
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U-insertion/deletion Edited Sequence Database by Simpson, Larry, Wang, Shirley H., Thiemann, Otavio H., Alfonzo, Juan D., Maslov, Dmitri A., Avila, Herbert A.

“…Uridine insertion/deletion RNA editing is a post-transcriptional RNA modification occurring in the mitochondria of kinetoplastid protozoa. The…”
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Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine–guanine phosphoribosyltransferase by Monzani, Paulo S., Alfonzo, Juan D., Simpson, Larry, Oliva, Glaucius, Thiemann, Otavio H.

“…Hypoxanthine–guanine phosphoribosyltransferase (HGPRT) (EC 2.4.2.8) is an important enzyme involved in the recycling of purine nucleotides in all cells…”
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Uridine insertion/deletion RNA editing in Leishmania tarentolae mitochondria shows cell cycle dependence by Carrillo, Robert, Thiemann, Otavio H., Alfonzo, Juan D., Simpson, Larry

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APT1, but not APT2, codes for a functional adenine phosphoribosyltransferase in Saccharomyces cerevisiae by Alfonzo, J.D, Crother, T.R, Guetsova, M.L, Daignan-Fornier, B, Taylor, M.W

“…The yeast Saccharomyces cerevisiae has two separate genes (APT1 and APT2) that encode two potentially different forms of adenine phosphoribosyltransferase…”
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The T. brucei TRM5 methyltransferase plays an essential role in mitochondrial protein synthesis and function by Paris, Zdenek, Horáková, Eva, Rubio, Mary Anne T, Sample, Paul, Fleming, Ian M C, Armocida, Stephanie, Lukes, Julius, Alfonzo, Juan D

“…All tRNAs undergo post-transcriptional chemical modifications as part of their natural maturation pathway. Some modifications, especially those in the…”
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Cloning and characterization of Leishmania tarentolae adenine phosphoribosyltransferase by Thiemann, Otavio H., Alfonzo, Juan D., Simpson, Larry

“…Leishmania tarentolae, a parasite of the gecko, has been exploited in our laboratory as a model trypanosomatid for a variety of molecular, biochemical and…”
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T7 RNA polymerase-driven transcription in mitochondria of Leishmania tarentolae and Trypanosoma brucei by Estévez, Antonio M, Thiemann, Otavio H, Alfonzo, Juan D, Simpson, Larry

“…The study of RNA editing and other molecular processes in the trypanosome mitochondrion would benefit greatly from the ability to insert and express exogenous…”
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Cloning and characterization of the adenine phosphoribosyltransferase-encoding gene (APT1) from Saccharomyces cerevisiae by Alfonzo, J D, Sahota, A, Deeley, M C, Ranjekar, P, Taylor, M W

“…We have cloned, sequenced and characterized the APT1 (adenine phosphoribosyltransferase) gene from Saccharomyces cerevisiae. The APT1 sequence includes an open…”
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C to U editing at position 32 of the anticodon loop precedes tRNA 5' leader removal in trypanosomatids by Gaston, Kirk W, Rubio, Mary Anne T, Spears, Jessica L, Pastar, Irena, Papavasiliou, F. Nina, Alfonzo, Juan D

“…In all organisms, precursor tRNAs are processed into mature functional units by post-transcriptional changes. These involve 5' and 3' end trimming as well as…”
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