Search Results - "Alfermann, A Wilhelm"

Lignans in flowering aerial parts of Linum species – Chemodiversity in the light of systematics and phylogeny by Schmidt, Thomas J., Hemmati, Shiva, Klaes, Michael, Konuklugil, Belma, Mohagheghzadeh, Abdolali, Ionkova, Iliana, Fuss, Elisabeth, Wilhelm Alfermann, A.

“…The lignan profiles of 41 Linum species as determined by HPLC-ESI/MS–MS are described and compared. Two major groups of species exist that accumulate…”
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production of cytotoxic lignans by plant cell cultures by Petersen, M, Alfermann, A.W

“…Cytotoxic lignans derived from podophyllotoxin are currently used in cancer chemotherapy. Podophyllotoxin for semi-synthetic derivation is isolated from the…”
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Biosynthesis of podophyllotoxin in Linum album cell cultures by Seidel, Véronique, Windhövel, Jörg, Eaton, Graham, Alfermann, A. Wilhelm, Arroo, Randolph R.J., Medarde, Manuel, Petersen, Maike, Woolley, Jack G.

“…Cell cultures of Linum album Kotschy ex Boiss. (Linaceae) showing high accumulation of the lignan podophyllotoxin (PTOX) were established. Enzymo-logical…”
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Aryltetralin-lignan formation in two different cell suspension cultures of Linum album: Deoxypodophyllotoxin 6-hydroxylase, a key enzyme for the formation of 6-methoxypodophyllotoxin by Federolf, Katja, Alfermann, A. Wilhelm, Fuss, Elisabeth

“…Suspension cultures initiated from two different Linum album seedlings accumulate either podophyllotoxin or 6-methoxypodophyllotoxin as main lignans due to the…”
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High-performance liquid chromatography/mass spectrometric identification of dibenzylbutyrolactone-type lignans: insights into electrospray ionization tandem mass spectrometric fragmentation of lign-7-eno-9,9′-lactones and application to the lignans of Linum usitatissimum L. (Common Flax) by Schmidt, Thomas J., Alfermann, A. Wilhelm, Fuss, Elisabeth

“…In continuation of our studies into the mass spectrometric detection of natural lignans and their identification in complex mixtures such as crude plant…”
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Pinoresinol-lariciresinol reductases with opposite enantiospecificity determine the enantiomeric composition of lignans in the different organs of Linum usitatissimum L by Hemmati, Shiva, von Heimendahl, Cosima B I, Klaes, Michael, Alfermann, A Wilhelm, Schmidt, Thomas J, Fuss, Elisabeth

“…Lignans in higher plants represent an ideal class of natural products to be investigated for the origin of stereochemical diversity since chiral lignans occur…”
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combined HPLC-UV and HPLC-MS method for the identification of lignans and its application to the lignans of Linum usitatissimum L. and L. bienne Mill by Schmidt, T.J, Hemmati, S, Fuss, E, Alfermann, A.W

“…A combined HPLC-UV/PAD and HPLC-ESI/MS method allowing the fast detection and identification/structural characterisation of lignans of different structural…”
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Justicidin B 7-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum perenne Himmelszelt involved in the biosynthesis of diphyllin by Hemmati, Shiva, Schneider, Bernd, Schmidt, Thomas J., Federolf, Katja, Alfermann, A. Wilhelm, Fuss, Elisabeth

“…A biosynthetic pathway for the formation of arylnaphthalene lignans like diphyllin is suggested. Justicidin B 7-hydroxylase (JusB7H) which catalyzes the last…”
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Metabolic profiling of lignan variability in Linum species of section Syllinum native to Bulgaria by Vasilev, Nikolay, Ebel, Rainer, Edrada, Ruangelie, Fuss, Elisabeth, Alfermann, A Wilhelm, Ionkova, Iliana, Petrova, Ana, Repplinger, Miriam, Schmidt, Thomas J

“…Lignans in eighteen samples of Linum species ( L. tauricum ssp. tauricum, serbicum, bulgaricum and linearifolium; L. elegans; L. flavum ssp. sparsiflorum, L…”
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Podophyllotoxin from suspension culture of Linum album by Sedaghat, Soheila, Ezatzadeh, Elham, Alfermann, A Wilhelm

“…Callus and suspension cultures of Linum album as an Iranian species for synthesis of aryltetralin lactone were used. After cultivation period; we can isolate…”
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Arylnaphthalene Lignans from in Vitro Cultures of Linum austriacum by Mohagheghzadeh, Abdolali, Schmidt, Thomas J, Alfermann, A. Wilhelm

“…Callus, suspension, and normal and hairy root cultures of Linum austriacum produced a new arylnaphthalene lignan,…”
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Diarylbutyrolactone lignans from Linum corymbulosum in vitro cultures by Mohagheghzadeh, Abdolali, Schmidt, Thomas J, Bayindir, Urün, Fuss, Elisabeth, Mehregan, Iraj, Alfermann, A Wilhelm

“…The arylbutyrolactone lignans (-)-hinokinin, 3,4 : 3',4'-bis(methylenedioxy)-lign-7( E)-en-9,9'-olide and 3,4 : 3',4'-bis(methylenedioxy)-lign-7(…”
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Stereochemistry of Lignans in Phaleria macrocarpa (Scheff.) Boerl by Saufi, Ahmad, von Heimendahl, Cosima B. I., Alfermann, A. Wilhelm, Fuss, Elisabeth

“…Phaleria macrocarpa (Scheff.) Boerl., a member of the Thymelaeaceae, is traditionally used in Indonesia as medicinal plant against cancer. In this context, we…”
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Root Cultures of Linum Species Section Syllinum as Rich Sources of 6-Methoxypodophyllotoxin by Mohagheghzadeh, Abdolali, Gholami, Azra, Hemmati, Shiva, Ardakani, Mohammad Reza Shams, Schmidt, Thomas J., Alfermann, A. Wilhelm

“…Linum spp. from section Syllinum are promising for the production of aryltetralin lignans like podophyllotoxin (PTOX) and 6-methoxypodophyllotoxin (MPTOX)…”
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Linum persicum: Lignans and placement in Linaceae by Mohagheghzadeh, Abdolali, Hemmati, Shiva, Mehregan, Iraj, Alfermann, A. Wilhelm

“…Aryltetralin lignans (podophyllotoxin type) are the main lignan constituents of species belonging to Linum section Syllinum (Linaceae). Linum persicum, a…”
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Linum mucronatum: Organ to Organ Lignan Variations by Mohagheghzadeh, Abdolali, Gholami, Azra, Soltani, Mohammad, Hemmati, Shiva, Alfermann, Wilhelm

“…The percentage of podophyllotoxin (PTOX) and its congener lignans were measured by HPLC in Linum mucronatum ssp. mucronatum (Linaceae) fresh plant organs. The…”
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Taxol® and baccatin III production in suspension cultures of Taxus baccata and Taxus wallichiana in an airlift bioreactor by Navia-Osorio, Alberto, Garden, Hermann, Cusidó, Rosa M., Palazón, Javier, Alfermann, A. Wilhelm, Piñol, M. Teresa

“…Suspension cultures of Taxus baccata var. fastigiata and Taxus wallichiana were grown in a 20-L airlift bioreactor running for 28 days in a batch mode, and…”
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Accumulation of podophyllotoxin and related lignans in cell suspension cultures of Linum album by SMOLLNY, T, WICHERS, H, KALENBERG, S, SHAHSAVARI, A, PETERSEN, M, ALFERMANN, A. W

“…Cell suspension cultures of Linum album were established, which were able to synthesize and accumulate lignans. Podophyllotoxin and 5-methoxypodophyllotoxin…”
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Accumulation of Lignans in Suspension Cultures of Linum mucronatum ssp. armenum (Bordz.) Davis by Konuklugil, Belma, Schmidt, Thomas J., Alfermann, A. Wilhelm

“…For the first time callus and suspension cultures of Li­num mucronatum ssp. armenum were initiated, grown in darkness at 25 °C and analyzed for lignans…”
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Production of the new antimalarial drug artemisinin in shoot cultures of Artemisia annua L by Woerdenbag, H.J. (Groningen Univ. (Netherlands). Dept. of Pharmacognosy), Lueers, J.F.J, Uden, W. van, Pras, N, Malingre, T.M, Alfermann, A.W

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