Search Results - "Alfaia, António J."

Exploring Drug Diffusion through a Membrane: A Physical Chemistry Experiment for Health and Life Sciences Undergraduate Students by Ribeiro, Isabel A. C, Faustino, Célia M. C, Guedes, Rita C, Alfaia, António J. I, Ribeiro, Maria H. L

“…The transport of molecules across biological membranes are critical for most cellular processes. Membrane permeability is also a key determinant for drug…”
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Enzymatic Synthesis of the Flavone Glucosides, Prunin and Isoquercetin, and the Aglycones, Naringenin and Quercetin, with Selective α-L-Rhamnosidase and β-D-Glucosidase Activities of Naringinase by Vila-Real, Hélder, Alfaia, António J., Bronze, M. Rosário, Calado, António R. T., Ribeiro, Maria H. L.

“…The production of flavonoid glycosides by removing rhamnose from rutinosides can be accomplished through enzymatic catalysis. Naringinase is an enzyme complex,…”
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Unusual Solvent Effect on a SN2 Reaction. A Quantum-Mechanical and Kinetic Study of the Menshutkin Reaction between 2-Amino-1-methylbenzimidazole and Iodomethane in the Gas Phase and in Acetonitrile by Melo, André, Alfaia, António J. I, Reis, João Carlos R, Calado, António R. T

“…The quaternization reaction between 2-amino-1-methylbenzimidazole and iodomethane was investigated in the gas phase and in liquid acetonitrile. Both…”
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α-Rhamnosidase and β-glucosidase expressed by naringinase immobilized on new ionic liquid sol–gel matrices: Activity and stability studies by Vila-Real, Helder, Alfaia, António J., Rosa, João N., Gois, Pedro M.P., Rosa, M. Emilia, Calado, António R.T., Ribeiro, Maria H.

“…Novel ionic liquid (IL) sol–gel materials development, for enzyme immobilization, was the goal of this work. The deglycosylation of natural glycosides were…”
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An innovative sol–gel naringinase bioencapsulation process for glycosides hydrolysis by Vila-Real, Helder, Alfaia, António J., Rosa, M. Emília, Calado, António R., Ribeiro, Maria H.L.

“…In this work, a biocatalytic system was chosen to enable the deglycosylation of natural glycosides in order to improve their biological activity. Naringinase,…”
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Contribution of response surface methodology to the modeling of naringin hydrolysis by naringinase Ca-alginate beads under high pressure by Ribeiro, Maria H.L., Afonso, Cristina, Vila-Real, Helder J., Alfaia, António J., Ferreira, Luís

“…Naringin is the dominant flavonoid bitter principle in grapefruit juice. The aim of this work was the modeling of the enzymatic hydrolysis of naringin, with…”
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High pressure-temperature effects on enzymatic activity: Naringin bioconversion by Vila Real, Helder J., Alfaia, António J., Calado, António R.T., Ribeiro, Maria H.L.

“…Initially exploited in chemistry and physics, high-pressure technology has gained importance in various fields. Flavonoids, namely naringin and naringenin,…”
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Pressure-enhanced activity and stability of α- l-rhamnosidase and β- d-glucosidase activities expressed by naringinase by Vila-Real, Helder, Alfaia, António J., Phillips, Robert S., Calado, António R., Ribeiro, Maria H.L.

“…Naringinase is an enzyme complex, expressing α- l-rhamnosidase and β- d-glucosidase activities. The impact of high pressure and temperature on naringinase…”
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Design of an immobilized enzyme system for naringin hydrolysis at high-pressure by Pedro, Helder A.L., Alfaia, António J., Marques, João, Vila-Real, Helder J., Calado, António, Ribeiro, Maria H.L.

“…The effect of pressure was studied in an enzymatic reaction with an immobilized biocatalyst. Naringinase immobilized by entrapment in calcium alginate beads…”
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Improvement of activity and stability of soluble and sol–gel immobilized naringinase in co-solvent systems by Vila-Real, Helder, Alfaia, António J., Calado, António R., Ribeiro, Maria H.L.

“…The hydrolysis of naringin, a bitter flavonone glycoside, with naringinase leads to reducing sugars (rhamnose and glucose), to prunin and to the aglycone,…”
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Irradiation effect on fatty acid composition and conjugated linoleic acid isomers in frozen lamb meat by Alfaia, Cristina M.M., Ribeiro, Paulo J.L.C., Trigo, Maria J.P., Alfaia, António J.I., Castro, Matilde L.F., Fontes, Carlos M.G.A., Bessa, Rui J.B., Prates, José A.M.

“…The effect of gamma radiation processing on the lipid content, fatty acid composition and conjugated linoleic acid (CLA) profile in frozen lamb meat was…”
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Modelling of the high pressure–temperature effects on naringin hydrolysis based on response surface methodology by Marques, João, Vila-Real, Helder J., Alfaia, António J., Ribeiro, Maria H.L.

“…The aim of this study was the modelling, under high pressure, of naringin hydrolysis by naringinase. Response surface methodology (RSM) was used to compare the…”
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High pressure: a tool to improve the enzymatic production of glycosides by Vila-Real, Helder, Alfaia, António J., Calado, António R., Phillips, Robert S., Ribeiro, Maria H.L.

“…Naringinase, an enzyme complex that expresses α -l-rhamnosidase and β -d-glucosidase activities in native state, can be used to deglycosylate natural…”
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α-Rhamnosidase and β-glucosidase expressed by naringinase immobilized on new ionic liquid sol-gel matrices: Activity and stability studies : Towards sustainable biotechnology by VILA-REAL, Helder, ALFAIA, António J, ROSA, João N, GOIS, Pedro M. P, ROSA, M. Emilia, CALADO, António R. T, RIBEIRO, Maria H

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Design of diglycerylsilane microcapsules for sol–gel bioencapsulation of naringinase: Activity and stability studies by Vila-Real, Helder, Alfaia, António J., Calado, António R., Ribeiro, Maria H.L.

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High pressure studies on hesperitin production with hesperidinase free and immobilized in calcium alginate beads by Furtado, Andreia, Rosário, Pedro M., Calado, António R.T., Alfaia, António J.I., Ribeiro, Maria H.L.

“…The use of high pressure for the enzymatic synthesis of pharmacologically interesting molecules is a very important tool. Hesperidin and hesperitin exhibit…”
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Unusual Solvent Effect on a S N 2 Reaction. A Quantum-Mechanical and Kinetic Study of the Menshutkin Reaction between 2-Amino-1-methylbenzimidazole and Iodomethane in the Gas Phase and in Acetonitrile by Melo, André, Alfaia, António J. I., Reis, João Carlos R., Calado, António R. T.

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High pressure and temperature combination with naringin hydrolysis by naringinase Ca-alginate beads in grapefruit juice processing: Bitterness and microbial reduction by Afonso, Cristina, Ferreira, Luís, Vila-Real, Hélder, Alfaia, António J., Ribeiro, Maria H.L.

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Development of co-solvent systems in the bioconversion of naringin to naringenin by naringinase by Vila-Real, Helder, J. Alfaia, António, R.T. Calado, António, H.L. Ribeiro, Maria

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Quaternization Reaction of Aromatic Heterocyclic Imines in Methanol − A Case of Strong Anti-Reactivity Selectivity Principle with Isoselective Temperature by Alfaia, António J. I., Calado, António R. T., Reis, João Carlos R.

“…Accurate second‐order rate constants were measured at 5 °C intervals in the temperature range 20−60 °C for the Menshutkin reaction of 1‐methylbenzimidazole,…”
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