Search Results - "Alfahed, Abdulaziz"

Cell Migration-Proliferation Dichotomy in Cancer: Biological Fact or Experimental Artefact? by Alfahed, Abdulaziz

“…The migration-proliferation dichotomy (MPD) has long been observed in cultured cancer cells. This phenomenon is not only relevant to tumour progression but may…”
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Therapeutic, Clinicopathological, and Molecular Correlates of PRKACA Expression in Gastrointestinal Cancers by Othaim, Ayoub Al, Alasiri, Glowi, Alfahed, Abdulaziz

“…alterations have clear diagnostic and biological roles in the fibrolamellar variant of hepatocellular carcinoma and a potential predictive role in that cancer…”
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Hematological and molecular analyses of the HbS allele among the Sudanese population by Khalafallah, Tariq Osman, Ajab Eldoor, Ahmed Abdalla, Babker, Asaad MA, Bin Shaya, Abdulkarim S., Alfahed, Abdulaziz, Alharithi, Nahed S., Aloraini, Ghfren S., Waggiallah, Hisham Ali

“…Objective The purpose of this study was to perform hematological and molecular analyses of the HbS allele of the hemoglobin subunit beta gene in the Sudanese…”
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Cten promotes Epithelial–Mesenchymal Transition (EMT) in colorectal cancer through stabilisation of Src by Asiri, Abdulaziz, Toss, Michael S., Raposo, Teresa Pereira, Akhlaq, Maham, Thorpe, Hannah, Alfahed, Abdulaziz, Asiri, Abutaleb, Ilyas, Mohammad

“…Cten is an oncogene promoting EMT in many signaling pathways, namely through Snail. We investigated whether Cten function could be mediated through Src. Cten…”
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The role of TAOK3 in cancer progression and development as a prognostic marker: A pan-cancer analysis study by Alasiri, Glowi, Alrfaei, Bahauddeen, Alaseem, Ali M., AlKhamees, Osama A., Aldali, Jehad A., Aljehani, Ala M., Alfahed, Abdulaziz, Aziz, Mohammad Azhar, Almuhaini, Ghadir, Alshehri, Mana M.

“…The protein kinase TAOK3, belongs to the MAP kinase family, is one of three closely related members, namely TAOK1, TAOK2, and TAOK3. We performed a pan-cancer…”
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Integrated exon level expression analysis of driver genes explain their role in colorectal cancer by Aziz, Mohammad Azhar, Periyasamy, Sathish, Al Yousef, Zeyad, AlAbdulkarim, Ibrahim, Al Otaibi, Majed, Alfahed, Abdulaziz, Alasiri, Glowi

“…Integrated analysis of genomic and transcriptomic level changes holds promise for a better understanding of colorectal cancer (CRC) biology. There is a…”
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A molecular informatics and in-vitro approach to evaluate the HMG-CoA reductase inhibitory efficacy of monoterpenes, carvacrol and geraniol by Almalki, Sami G., Alsaweed, Mohammed, Muteb Albadrani, Hind, Alqurashi, Yaser E., Bazuhair, Mohammed A., Ahmed, Hamzah H., Ahmad, Parvej, Alfahed, Abdulaziz, Al Othaim, Ayoub, Iqbal, Danish

“…Currently, statins, the β-hydroxy-β-methyl-glutaryl-CoA reductase (HMG-R) inhibitors, are widely used to lower cholesterol, nevertheless, they have…”
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Detection of human platelets antigen polymorphism (HPA-1 and HPA-3) and human factor XIII mutation in Sudanese women with recurrent pregnancy loss by Babker, Asaad Ma, Fadlalmula, Huda Ahamed, Gamal G Elggourish, Amanda, Ahmed, Hanan Khalid Fadul, Yousri Masoud Awad, Shima, Elzaki, Salaheldein G, Suliman, Rania Saad, Bin Shaya, Abdulkarim S, Alfahed, Abdulaziz, Alharthi, Nahed S, Hjazi, Ahmed M, Hakami, Nora Y, Hakami, Mohammed Ageeli, Almotiri, Alhomidi, Waggiallah, Hisham Ali

“…Recurrent pregnancy Loss (RPL) is common problem affecting many couples. A certain genetic variants link to increase the danger of this condition particularly…”
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Expression of P53 and PTEN in Correlation with some Clinical and Pathological Features in Breast Cancer of Sudanese Patients by Hamad, Abubaker, Alkhatem, Rania, Algahany, Asaad, Ahmed, Hussain, Alfahed, Abdulaziz, Waggiallah, Hisham

“…The goal of our study was to determine the expression and phosphorylation of PTEN at residues Ser380/Thr382/383, as well as the nuclear expression of p53 in…”
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Molecular pathology of colorectal cancer: The Saudi situation in perspective by Alfahed, Abdulaziz

“…Colorectal cancer (CRC) is one of the most common cancers worldwide, and one of the most common causes of cancer deaths. In recent times, significant…”
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Deregulation of TWIST1 expression by promoter methylation in gastrointestinal cancers by Alfahed, Abdulaziz

“…TWIST1, a basic helix-loop-helix transcription factor with versatile roles in cancer, is frequently deregulated in cancers, through established pathway…”
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Chromosome-specific segment size alterations are determinants of prognosis in prostate cancer by Alfahed, Abdulaziz, Ebili, Henry Okuchukwu, Waggiallah, Hisham Ali

“…Currently, risk stratification is the most difficult problem in prostate cancer (PCa) management. Gleason grading cannot adequately predict cancer progression…”
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TGFβ1‐induced cell motility but not cell proliferation is mediated through Cten in colorectal cancer by Asiri, Abdulaziz, Raposo, Teresa Pereira, Alfahed, Abdulaziz, Ilyas, Mohammad

“…Summary Cten (C‐terminal tensin‐like) is a member of the tensin protein family found in complex with integrins at focal adhesions. It promotes…”
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Role and Regulation of Cten in Colorectal Cancer by Alfahed, Abdulaziz

“…C-terminal tensin-like (CTEN), also called Tensin4 (TNS4), is the fourth member of the tensin family. The function of CTEN is tissue dependent; it acts as an…”
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Tensin4 (TNS4) is upregulated by Wnt signalling in adenomas in multiple intestinal neoplasia (Min) mice by Raposo, Teresa P., Alfahed, Abdulaziz, Nateri, Abdolrahman S., Ilyas, Mohammad

“…Summary ApcMin/+ mice are regarded as a standard animal model of colorectal cancer (CRC). Tensin4 (TNS4 or Cten) is a putative oncogene conferring features of…”
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Detection of Methylene Tetrahydrofolate Reductase (MTHFR C677T) Mutation among Acute Lymphoblastic Leukemia in Sudanese Patients by Mohieldeen, Waad Almuatasem, Ahmed, Albara, Elmosaad, Yousif Mohammed, Suliman, Rania Saad, Alfahed, Abdulaziz, Hjazi, Ahmed, Al Shmrany, Humood, Hakami, Nora, Hakami, Mohammed Ageeli, Almotiri, Alhomidi, Waggiallah, Hisham Ali

“…A genetic polymorphism that causes abnormal folate metabolism may lead to genomic instability and increase susceptibility to malignancies such as Acute…”
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Prognostic Values of Gene Copy Number Alterations in Prostate Cancer by Alfahed, Abdulaziz, Ebili, Henry Okuchukwu, Almoammar, Nasser Eissa, Alasiri, Glowi, AlKhamees, Osama A, Aldali, Jehad A, Al Othaim, Ayoub, Hakami, Zaki H, Abdulwahed, Abdulhadi M, Waggiallah, Hisham Ali

“…Whilst risk prediction for individual prostate cancer (PCa) cases is of a high priority, the current risk stratification indices for PCa management have severe…”
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Comparative analysis of immunological biomarkers in COVID-19 and bacterial pneumonia by Abakar, Mudathir Abdelshafea Abdelkareem, Hamad, Daralnaeem Hassan Ali, Faisal, Eman, Omer, Hashim Mohamed Fad-Alla, Faki, Mahmoud Taha Mohamed, Idris, Abdellla Esmail Mohammed, Omer, Rouwida, Osman, Zeinab, Elhassan, Entesar Ahmed Gaffar, Abrahim-Holie, Mohamed Ahmed, Hakami, Mohammed Ageeli, Alghamdi, Abdullah, Alfahed, Abdulaziz, Aloraini, Ghfren Suliman, Alharthi, Nahed Sail, Waggiallah, Hisham Ali

“…Coronavirus disease 2019 (COVID-19) is a severe and infectious respiratory condition caused by the Severe Acute Respiratory Syndrome Coronavirus 2…”
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Alternatively Spliced Isoforms of MUC4 and ADAM12 as Biomarkers for Colorectal Cancer Metastasis by Althenayyan, Saleh, AlMuhanna, Mohammed H, AlAbdulrahman, Abdulkareem, Alghanem, Bandar, Alsagaby, Suliman A, Alfahed, Abdulaziz, Alasiri, Glowi, Aziz, Mohammad Azhar

“…There is a pertinent need to develop prognostic biomarkers for practicing predictive, preventive and personalized medicine (PPPM) in colorectal cancer…”
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Integrated Exon Level Expression Analysis of Driver Genes Explain Their Role in Colorectal Cancer: e110134 by Aziz, Mohammad Azhar, Periyasamy, Sathish, Yousef, Zeyad Al, AlAbdulkarim, Ibrahim, Otaibi, Majed Al, Alfahed, Abdulaziz, Alasiri, Glowi

“…Integrated analysis of genomic and transcriptomic level changes holds promise for a better understanding of colorectal cancer (CRC) biology. There is a…”
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