Search Results - "Alfa, Michelle J."

A randomized trial to determine the impact of a digestion resistant starch composition on the gut microbiome in older and mid-age adults by Alfa, Michelle J, Strang, David, Tappia, Paramjit S, Graham, Morag, Van Domselaar, Gary, Forbes, Jessica D, Laminman, Vanessa, Olson, Nancy, DeGagne, Pat, Bray, David, Murray, Brenda-Lee, Dufault, Brenden, Lix, Lisa M

“…Summary Background The elderly often have a diet lacking resistant starch (RS) which is thought to lead to gut microbiome dysbiosis that may result in…”
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Validation of adenosine triphosphate to audit manual cleaning of flexible endoscope channels by Alfa, Michelle J., PhD, Fatima, Iram, MSc, Olson, Nancy, BSc

“…Background Compliance with cleaning of flexible endoscope channels cannot be verified using visual inspection. Adenosine triphosphate (ATP) has been suggested…”
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Monitoring and improving the effectiveness of cleaning medical and surgical devices by Alfa, Michelle J., PhD, FCCM

“…The overall risk of infection from medical devices is very low, but high infection transmission rates have been related to inadequate reprocessing of…”
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Current issues result in a paradigm shift in reprocessing medical and surgical instruments by Alfa, Michelle J., PhD

“…Highlights • Outbreaks associated with improper reprocessing of medical instruments and flexible endoscopes have highlighted the importance of cleaning. • FDA…”
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The adenosine triphosphate test is a rapid and reliable audit tool to assess manual cleaning adequacy of flexible endoscope channels by Alfa, Michelle J., PhD, Fatima, Iram, MSc, Olson, Nancy, BSc

“…Background The study objective was to verify that the adenosine triphosphate (ATP) benchmark of <200 relative light units (RLUs) was achievable in a busy…”
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Identification of Blood Culture Isolates Directly from Positive Blood Cultures by Use of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry and a Commercial Extraction System: Analysis of Performance, Cost, and Turnaround Time by LAGACE-WIENS, Philippe R. S, ADAM, Heather J, KARLOWSKY, James A, NICHOL, Kimberly A, PANG, Paulette F, GUENTHER, Jodi, WEBB, Amanda A, MILLER, Crystal, ALFA, Michelle J

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Consumption of Solnul ™ Resistant Potato Starch Produces a Prebiotic Effect in a Randomized, Placebo-Controlled Clinical Trial by Bush, Jason R, Baisley, Joshua, Harding, Scott V, Alfa, Michelle J

“…The effects of resistant starch at high doses have been well-characterized, but the potential prebiotic effects of resistant starch at doses comparable to…”
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Increasing levels of Parasutterella in the gut microbiome correlate with improving low-density lipoprotein levels in healthy adults consuming resistant potato starch during a randomised trial by Bush, Jason R, Alfa, Michelle J

“…Prebiotics, defined as a substrate that is selectively utilized by host microorganisms conferring a health benefit, present a potential option to optimize gut…”
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Comparison of clinically relevant benchmarks and channel sampling methods used to assess manual cleaning compliance for flexible gastrointestinal endoscopes by Alfa, Michelle J., PhD, Olson, Nancy, BSc, Murray, Brenda-Lee, MSc

“…Background The objectives of this study were to recommend sample collection method(s) based on relative soiling in patient-used gastrointestinal (GI)…”
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Use of a daily disinfectant cleaner instead of a daily cleaner reduced hospital-acquired infection rates by Alfa, Michelle J., PhD, Lo, Evelyn, MD, Olson, Nancy, BSc, MacRae, Michelle, Buelow-Smith, Louise, RN

“…Background Documenting effective approaches to eliminate environmental reservoirs and reduce the spread of hospital-acquired infections (HAIs) has been…”
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A novel polytetrafluoroethylene-channel model, which simulates low levels of culturable bacteria in buildup biofilm after repeated endoscope reprocessing by Alfa, Michelle J., PhD, Ribeiro, Maira M., PhD, da Costa Luciano, Cristiana, PhD, Franca, Rodrigo, PhD, Olson, Nancy, BSc, DeGagne, Pat, RT, Singh, Harminder, MD

“…Background and Aims Clinical studies have shown variable culture results from flexible endoscope channels possibly because of low levels of bacteria that are…”
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Simulated-use validation of a sponge ATP method for determining the adequacy of manual cleaning of endoscope channels by Alfa, Michelle J, Olson, Nancy

“…The objective of this study was to validate the relative light unit (RLU) cut-off of adequate cleaning of flexible colonoscopes for an ATP (adenosine…”
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Microfiber cloths reduce the transfer of Clostridium difficile spores to environmental surfaces compared with cotton cloths by Trajtman, Adriana N., MSc, Manickam, Kanchana, PhD, Alfa, Michelle J., PhD

“…Background Environmental surfaces in health care facilities contaminated with Clostridium difficile spores can be a reservoir that contribute to transmission…”
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Modeling microbial survival in buildup biofilm for complex medical devices by Alfa, Michelle J, Howie, Rosemarie

“…Flexible endoscopes undergo repeated rounds of patient-use and reprocessing. Some evidence indicates that there is an accumulation or build-up of organic…”
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Impact of wet storage and other factors on biofilm formation and contamination of patient-ready endoscopes: a narrative review by Alfa, Michelle J., Singh, Harminder

“…The 2019 U.S. Food and Drug Administration report indicates that the clinical studies undertaken by the 3 main GI endoscope manufacturers demonstrate 5.4% of…”
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Establishing a clinically relevant bioburden benchmark: A quality indicator for adequate reprocessing and storage of flexible gastrointestinal endoscopes by Alfa, Michelle J., PhD, FCCM, Sepehri, Shadi, MD, PhD, Olson, Nancy, BSc, Wald, Alana

“…Background Microbiological surveillance of patient-ready flexible endoscopes has been suggested as a tool for endoscope reprocessing quality assurance…”
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Biofilms on instruments and environmental surfaces: Do they interfere with instrument reprocessing and surface disinfection? Review of the literature by Alfa, Michelle J.

“…•Traditional biofilm differs from build-up biofilm and dry surface biofilm.•Build-up biofilm is common in endoscope channels and may lead to infection.•Dry…”
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Development and validation of rapid use scope test strips to determine the efficacy of manual cleaning for flexible endoscope channels by Alfa, Michelle J., PhD, Olson, Nancy, BSc, RT, DeGagné, Pat, RT, Simner, Patricia J., PhD

“…Background Cleaning of flexible endoscopes is most commonly performed using manual methods that are often performed inadequately. The aim of this study was to…”
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Comparison of washer-disinfector cleaning indicators: Impact of temperature and cleaning cycle parameters by Alfa, Michelle J., PhD, FCCM, Olson, Nancy, BSc

“…Background Because automated instrument washer-disinfectors (WD) are widely used in health care to reprocess a variety of medical instruments, we developed a…”
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Medical instrument reprocessing: current issues with cleaning and cleaning monitoring by Alfa, Michelle J.

“…•Reprocessing of medical devices requires a quality management system.•Contaminated surgical instruments and endoscopes have caused infection…”
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