Search Results - "Alexy, Eric J."

Catalytic Enantioselective Synthesis of Acyclic Quaternary Centers: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully Substituted Acyclic Enol Carbonates by Alexy, Eric J, Zhang, Haiming, Stoltz, Brian M

“…The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted acyclic enol carbonates providing linear α-quaternary…”
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Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted N -acyl indole-derived enol carbonates by Alexy, Eric J, Fulton, Tyler J, Zhang, Haiming, Stoltz, Brian M

“…The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted -acyl indole-derived enol carbonates forming acyclic…”
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Tailoring Panchromatic Absorption and Excited-State Dynamics of Tetrapyrrole–Chromophore (Bodipy, Rylene) ArraysInterplay of Orbital Mixing and Configuration Interaction by Mandal, Amit Kumar, Diers, James R, Niedzwiedzki, Dariusz M, Hu, Gongfang, Liu, Rui, Alexy, Eric J, Lindsey, Jonathan S, Bocian, David F, Holten, Dewey

“…Three sets of tetrapyrrole–chromophore arrays have been examined that exhibit panchromatic absorption across large portions of the near-ultraviolet (NUV) to…”
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Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Acyclic α- N -Pyrrolyl/Indolyl Ketones by Lavernhe, Remi, Alexy, Eric J, Zhang, Haiming, Stoltz, Brian M

“…The synthesis of fully substituted α- -pyrrolyl and indolyl ketones via enantioselective palladium-catalyzed allylic alkylation is described. The acyclic…”
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Enantioselective γ‑Alkylation of α,β-Unsaturated Malonates and Ketoesters by a Sequential Ir-Catalyzed Asymmetric Allylic Alkylation/Cope Rearrangement by Liu, Wen-Bo, Okamoto, Noriko, Alexy, Eric J, Hong, Allen Y, Tran, Kristy, Stoltz, Brian M

“…A catalytic, enantioselective γ-alkylation of α,β-unsaturated malonates and ketoesters is reported. This strategy entails a highly regio- and enantioselective…”
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Asymmetric Total Synthesis of Havellockate by Hafeman, Nicholas J., Chan, Melinda, Fulton, Tyler J., Alexy, Eric J., Loskot, Steven A., Virgil, Scott. C., Stoltz, Brian M.

“…The first total synthesis of the furanobutenolide-derived cembranoid diterpenoid havellockate is disclosed. Our convergent strategy employs a Julia–Kocienski…”
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Palladium‐Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Protected Benzoin‐Derived Enol Carbonates by Lavernhe, Rémi, Alexy, Eric J., Zhang, Haiming, Stoltz, Brian M.

“…The enantioselective palladium‐catalyzed decarboxylative allylic alkylation of fully substituted α‐hydroxy acyclic enol carbonates providing tetrasubstituted…”
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Global Diastereoconvergence in the Ireland–Claisen Rearrangement of Isomeric Enolates: Synthesis of Tetrasubstituted α‑Amino Acids by Fulton, Tyler J, Cusumano, Alexander Q, Alexy, Eric J, Du, Yun E, Zhang, Haiming, Houk, K. N, Stoltz, Brian M

“…A dual experimental/theoretical investigation of the Ireland–Claisen rearrangement of tetrasubstituted α-phthalimido ester enolates to afford…”
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Enantioselective Pd-Catalyzed Decarboxylative Allylic Alkylation of Thiopyranones. Access to Acyclic, Stereogenic α‑Quaternary Ketones by Alexy, Eric J, Virgil, Scott C, Bartberger, Michael D, Stoltz, Brian M

“…A catalytic, enantioselective decarboxylative allylic alkylation of 4-thiopyranones is reported. The α-quaternary 4-thiopyranones produced are challenging to…”
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Stereospecific Overman Rearrangement of Substituted Cyclic Vinyl Bromides: Access to Fully Substituted α‑Amino Ketones by Velasco-Rubio, Álvaro, Alexy, Eric J, Yoritate, Makoto, Wright, Austin C, Stoltz, Brian M

“…A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tertiary allylic amines has been developed. The vinyl bromide…”
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Palladium-catalyzed α,β-dehydrogenation of acyclic ester equivalents promoted by a novel electron deficient phosphinooxazoline ligand by Fulton, Tyler J., Wu, Brenda, Alexy, Eric J., Zhang, Haiming, Stoltz, Brian M.

“…A unique example of Pd-catalyzed decarboxylative dehydrogenation of fully substituted N-acyl allyl enol carbonates is enabled by a new electron deficient…”
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Origin of Panchromaticity in Multichromophore–Tetrapyrrole Arrays by Yuen, Jonathan M, Diers, James R, Alexy, Eric J, Roy, Arpita, Mandal, Amit Kumar, Kang, Hyun Suk, Niedzwiedzki, Dariusz M, Kirmaier, Christine, Lindsey, Jonathan S, Bocian, David F, Holten, Dewey

“…Panchromatic absorbers that have robust photophysical properties enable new designs for molecular-based light-harvesting systems. Herein, we report…”
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Paley's watchmaker analogy and prebiotic synthetic chemistry in surfactant assemblies. Formaldehyde scavenging by pyrroles leading to porphyrins as a case study by Alexy, Eric J, Hintz, Carl W, Hughes, Hubert M, Taniguchi, Masahiko, Lindsey, Jonathan S

“…The formation of elaborate molecules is regarded as an essential first step in prebiotic chemistry, but how such transformations could spontaneously occur,…”
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Tuning the Electronic Structure and Properties of Perylene–Porphyrin–Perylene Panchromatic Absorbers by Amanpour, Javad, Hu, Gongfang, Alexy, Eric J, Mandal, Amit Kumar, Kang, Hyun Suk, Yuen, Jonathan M, Diers, James R, Bocian, David F, Lindsey, Jonathan S, Holten, Dewey

“…Light-harvesting architectures that afford strong absorption across the near-ultraviolet to near-infrared region, namely, panchromatic absorptivity, are…”
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Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates† †Electronic supplementary information (ESI) available: Experimental procedures, NMR and IR spectra, SFC traces, X-ray crystallographic data. CCDC 1908785. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c9sc01726g by Alexy, Eric J., Fulton, Tyler J., Zhang, Haiming, Stoltz, Brian M.

“…The first enantioselective Pd-catalyzed decarboxylative allylic alkylation of fully substituted N -acyl indole-derived enol carbonates generates acyclic…”
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Development of Enantioselective Transition-Metal Catalyzed Allylic Alkylation Methodologies by Alexy, Eric J

“…Research in the Stoltz group is directed, generally, at the development of synthetic methods for the preparation of stereochemically rich molecules, and the…”
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Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted -acyl indole-derived enol carbonates by Alexy, Eric J, Fulton, Tyler J, Zhang, Haiming, Stoltz, Brian M

“…The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted N -acyl indole-derived enol carbonates forming acyclic…”
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