Search Results - "Alexopoulos, L"

Laser activated single-use micropumps by Kanakaris, G.P., Fatsis-Kavalopoulos, N., Alexopoulos, L.G.

“…•We present a novel thermal micropumping method for Point of Care applications.•The method is based on expandable microspheres, photopolymers and laser…”
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Quantifying Cartilage Biomechanical Properties Using a Linearized Frequency-Domain Method by Gkousioudi, A., Tzeranis, D. S., Kanakaris, G. P., Saloufas, M., Alexopoulos, L. G.

“…Articular cartilage function relies on its unique mechanical behavior. Cartilage mechanics have been described by several analytic models, whose parameters are…”
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A device for high-throughput monitoring of degradation in soft tissue samples by Tzeranis, D.S., Panagiotopoulos, I., Gkouma, S., Kanakaris, G., Georgiou, N., Vaindirlis, N., Vasileiou, G., Neidlin, M., Gkousioudi, A., Spitas, V., Macheras, G.A., Alexopoulos, L.G.

“…This work describes the design and validation of a novel device, the High-Throughput Degradation Monitoring Device (HDD), for monitoring the degradation of 24…”
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Modeling of signaling pathways in chondrocytes based on phosphoproteomic and cytokine release data by Melas, I.N, Chairakaki, A.D, Chatzopoulou, E.I, Messinis, D.E, Katopodi, T, Pliaka, V, Samara, S, Mitsos, A, Dailiana, Z, Kollia, P, Alexopoulos, L.G

“…Summary Objective Chondrocyte signaling is widely identified as a key component in cartilage homeostasis. Dysregulations of the signaling processes in…”
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Comparison of Goldmann and Pascal tonometry in relation to corneal hysteresis and central corneal thickness in nonglaucomatous eyes by Mangouritsas, G, Mourtzoukos, S, Mantzounis, A, Alexopoulos, L

“…To compare measurements obtained by Goldmann applanation tonometry (GAT) and Pascal dynamic contour tonometry (DCT), and to study their relationship to corneal…”
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Micro-bead immunoassays for the detection of IL6 and PDGF-2 proteins on a microfluidic platform, incorporating superhydrophobic passive valves by Ellinas, K., Pliaka, V., Kanakaris, G., Tserepi, A., Alexopoulos, L.G., Gogolides, E.

“…A microfluidic platform optimized for bead-based immunoassays is presented. It uses a simple design that incorporates passive valves in the inlet and outlet of…”
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Network‐Based Analysis of Nutraceuticals in Human Hepatocellular Carcinomas Reveals Mechanisms of Chemopreventive Action by Michailidou, M, Melas, IN, Messinis, DE, Klamt, S, Alexopoulos, LG, Kolisis, FN, Loutrari, H

“…Chronic inflammation is associated with the development of human hepatocellular carcinoma (HCC), an essentially incurable cancer. Anti‐inflammatory…”
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A method for quantifying cell size from differential interference contrast images: validation and application to osmotically stressed chondrocytes by Alexopoulos, L. G., Erickson, G. R., Guilak, F.

“…Summary An automatic image analysis method was developed to determine the shape and size of spheroidal cells from a time series of differential interference…”
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280 Systems Biology Approach and High-throughput Proteomic Analysis Identifies Toll-Like-Receptor Activators as Major Players of Cartilage Degeneration by Alexopoulos, L, Chairakaki, A, Melas, I, Provatidis, C, Kolia, P, Dailiana, Z

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Alterations in the mechanical properties of the human chondrocyte pericellular matrix with osteoarthritis by Alexopoulos, Leonidas G, Haider, Mansoor A, Vail, Thomas P, Guilak, Farshid

“…In articular cartilage, chondrocytes are surrounded by a pericellular matrix (PCM), which together with the chondrocyte have been termed the "chondron." While…”
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Hyper-osmotic stress induces volume change and calcium transients in chondrocytes by transmembrane, phospholipid, and G-protein pathways by Erickson, Geoffrey R, Alexopoulos, Leonidas G, Guilak, Farshid

“…Mechanical compression of cartilage is associated with a rise in the interstitial osmotic pressure, which can alter cell volume and activate volume recovery…”
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Automated standardized pupillometry with optical method for purposes of clinical practice and research by Fotiou, F., Fountoulakis, K. N., Goulas, A., Alexopoulos, L., Palikaras, A.

“…The aim of the current study was the introduction and standardization of two experimental conditions for dynamic pupillometry. Pupillometry is a method that…”
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Association of ICAM-1 with low left ventricular ejection fraction in patients with advanced coronary artery disease by Samanidis, G., Gkogkos, A., Alexopoulos, L., Perreas, K., Perrea, D.

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Promising biomarkers in patients with advanced coronary artery disease by Samanidis, G., Gkogkos, A., Doulamis, I., Tzani, A., Alexopoulos, L., Perreas, K., Perrea, D.

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Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining by Vougas, Konstantinos, Sakellaropoulos, Theodore, Kotsinas, Athanassios, Foukas, George-Romanos P., Ntargaras, Andreas, Koinis, Filippos, Polyzos, Alexander, Myrianthopoulos, Vassilios, Zhou, Hua, Narang, Sonali, Georgoulias, Vassilis, Alexopoulos, Leonidas, Aifantis, Iannis, Townsend, Paul A., Sfikakis, Petros, Fitzgerald, Rebecca, Thanos, Dimitris, Bartek, Jiri, Petty, Russell, Tsirigos, Aristotelis, Gorgoulis, Vassilis G.

“…A major challenge in cancer treatment is predicting the clinical response to anti-cancer drugs on a personalized basis. The success of such a task largely…”
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Chios mastic gum inhibits diet-induced non-alcoholic steatohepatitis in mice via activation of PPAR-α by Tzani, A., Konstantopoulos, P., Doulamis, I., Liakea, A., Minia, A., Antoranz, A., Korou, L.-M., Kavantzas, N., Alexopoulos, L., Stamatelopoulos, K., Iliopoulos, D., Perrea, D.

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Resistin and ICAM-1 as highly expessed proteins in epicardial adipose tissue by Karampetsou, N., Bletsa, E., Oikonomou, E., Pliaka, V., Minia, A., Patapis, P., Kontzoglou, K., Alexopoulos, L., Tousoulis, D., Perrea, D., Chloroyiannis, I.A.

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Investigations of cytokine interplay with an in vitro model of osteoarthritis by Neidlin, M., Chantzi, E., Macheras, G., Gustafsson, M., Alexopoulos, L.

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Tumor necrosis factor (TNF) superfamily members 10 and 12 are associated with the metabolic health status of morbid obese patients by Doulamis, I., Konstantopoulos, P., Tzani, A., Antoranz, A., Daskalopoulou, A., Minia, A., Charalampopoulos, A., Perrea, Dn, Alexopoulos, L., Menenakos, E.

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Proteomic discovery of biomarkers associated with morbid obesity in patients undergoing bariatric surgery by Doulamis, I., Konstantopoulos, P., Tzani, A., Antoranz, A., Daskalopoulou, A., Minia, A., Charalampopoulos, A., Perrea, D.N., Alexopoulos, L., Menenakos, E.

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