Search Results - "Alexopoulos, J."

Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice by Alexopoulos, Stephanie J., Chen, Sing-Young, Brandon, Amanda E., Salamoun, Joseph M., Byrne, Frances L., Garcia, Christopher J., Beretta, Martina, Olzomer, Ellen M., Shah, Divya P., Philp, Ashleigh M., Hargett, Stefan R., Lawrence, Robert T., Lee, Brendan, Sligar, James, Carrive, Pascal, Tucker, Simon P., Philp, Andrew, Lackner, Carolin, Turner, Nigel, Cooney, Gregory J., Santos, Webster L., Hoehn, Kyle L.

“…Obesity is a health problem affecting more than 40% of US adults and 13% of the global population. Anti-obesity treatments including diet, exercise, surgery…”
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Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3) by Knights, Alexander J., Vohralik, Emily J., Houweling, Peter J., Stout, Elizabeth S., Norton, Laura J., Alexopoulos, Stephanie J., Yik, Jinfen. J., Mat Jusoh, Hanapi, Olzomer, Ellen M., Bell-Anderson, Kim S., North, Kathryn N., Hoehn, Kyle L., Crossley, Merlin, Quinlan, Kate G. R.

“…The conversion of white adipocytes to thermogenic beige adipocytes represents a potential mechanism to treat obesity and related metabolic disorders. However,…”
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BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control by Axelrod, Christopher L, King, William T, Davuluri, Gangarao, Noland, Robert C, Hall, Jacob, Hull, Michaela, Dantas, Wagner S, Zunica, Elizabeth RM, Alexopoulos, Stephanie J, Hoehn, Kyle L, Langohr, Ingeborg, Stadler, Krisztian, Doyle, Haylee, Schmidt, Eva, Nieuwoudt, Stephan, Fitzgerald, Kelly, Pergola, Kathryn, Fujioka, Hisashi, Mey, Jacob T, Fealy, Ciaran, Mulya, Anny, Beyl, Robbie, Hoppel, Charles L, Kirwan, John P

“…Obesity is a leading cause of preventable death worldwide. Despite this, current strategies for the treatment of obesity remain ineffective at achieving…”
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Personality Functioning and Self-Disorders in different stages of Psychotic Disorders and Borderline Personality Disorder by Gruber, M., Alexopoulos, J., Feichtinger, K., Parth, K., Wininger, A., Mossaheb, N., Friedrich, F., Litvan, Z., Hinterbuchinger, B., Doering, S., Blüml, V.

“…Introduction Personality functioning, self-disorders and their relationship to psychotic symptoms on a continuum from mild attenuated experiences to manifest…”
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Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice by Chen, Sing-Young, Beretta, Martina, Olzomer, Ellen M., Shah, Divya P., Wong, Derek Y.H., Alexopoulos, Stephanie J., Aleksovska, Isabella, Salamoun, Joseph M., Garcia, Christopher J., Cochran, Blake J., Rye, Kerry-Anne, Smith, Greg C., Byrne, Frances L., Morris, Margaret J., Santos, Webster L., Cantley, James, Hoehn, Kyle L.

“…Calorie restriction is a first-line treatment for overweight individuals with metabolic impairments. However, few patients can adhere to long-term calorie…”
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Sparse and incomplete factorial matrices to screen membrane protein 2D crystallization by Lasala, R., Coudray, N., Abdine, A., Zhang, Z., Lopez-Redondo, M., Kirshenbaum, R., Alexopoulos, J., Zolnai, Z., Stokes, D.L., Ubarretxena-Belandia, I.

“…Electron crystallography is well suited for studying the structure of membrane proteins in their native lipid bilayer environment. This technique relies on…”
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Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15 by Zunica, Elizabeth R. M., Axelrod, Christopher L., Cho, Eunhan, Spielmann, Guillaume, Davuluri, Gangarao, Alexopoulos, Stephanie J., Beretta, Martina, Hoehn, Kyle L., Dantas, Wagner S., Stadler, Krisztian, King, William T., Pergola, Kathryn, Irving, Brian A., Langohr, Ingeborg M., Yang, Shengping, Hoppel, Charles L., Gilmore, L. Anne, Kirwan, John P.

“…Abstract Background Enhanced metabolic plasticity and diversification of energy production is a hallmark of highly proliferative breast cancers. This…”
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Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress by Byrne, Frances L., Olzomer, Ellen M., Marriott, Gabriella R., Quek, Lake-Ee, Katen, Alice, Su, Jacky, Nelson, Marin E., Hart-Smith, Gene, Larance, Mark, Sebesfi, Veronica F., Cuff, Jeff, Martyn, Gabriella E., Childress, Elizabeth, Alexopoulos, Stephanie J., Poon, Ivan K., Faux, Maree C., Burgess, Antony W., Reid, Glen, McCarroll, Joshua A., Santos, Webster L., Quinlan, Kate GR, Turner, Nigel, Fazakerley, Daniel J., Kumar, Naresh, Hoehn, Kyle L.

“…A hallmark of cancer cells is their ability to reprogram nutrient metabolism. Thus, disruption to this phenotype is a potential avenue for anti-cancer therapy…”
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Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential by Childress, Elizabeth S, Alexopoulos, Stephanie J, Hoehn, Kyle L, Santos, Webster L

“…Small molecule mitochondrial uncouplers transport protons from the mitochondrial inner membrane space into the mitochondrial matrix independent of ATP…”
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Statistical Analysis of Cortical Morphometrics Using Pooled Distances Based on Labeled Cortical Distance Maps by Ceyhan, E., Hosakere, M., Nishino, T., Alexopoulos, J., Todd, R. D., Botteron, K. N., Miller, M. I., Ratnanather, J. T.

“…Neuropsychiatric disorders have been demonstrated to manifest shape differences in cortical structures. Labeled Cortical Distance Mapping (LCDM) is a powerful…”
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Facial cues affect the feedback negativity to offers in the Ultimatum Game. An EEG investigation by Schreiner, T., Alexopoulos, J., Pfabigan, D.M., Sailer, U.

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Effects of antisocial personality traits on event-related potentials during face processing by Pfabigan, D.M., Alexopoulos, J., Kryspin-Exner, I., Sailer, U.

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Modelling of two-phase incompressible flows in ducts by Christafakis, A., Alexopoulos, J., Tsangaris, S.

“…An improved level-set method for capturing interfaces combined with a second-order projection method for solving the time-dependent incompressible…”
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The role of neuroestrogens in the estrogen‐induced gonadotropin surge in male monkeys by Biswas, Mohammad S., Gelman, Erica M., Alexopoulos, Daniel J., Keen, Kim L., Adam, Ryan J., Terasawa, Ei

“…Neuroestrogens locally synthesized in the brain are known to play a role in sexual behaviors. However, the question of whether neuroestrogens are involved in…”
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A74 Comparative study between dynamic condylar screw and retrograde intramedullary nail for the treatment of femoral supracondylar fractures by Paraschou, S, Anastasopoulos, H, Chatziliadis, G, Papapanos, A, Alexopoulos, J, Karanikolas, A, Veltsistas, K

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A83 Treatment of humeral shaft fractures with intramedullary nailing by Paraschou, S, Anastasopoulos, H, Chatziliadis, G, Papapanos, A, Alexopoulos, J, Karanikolas, A, Veltsistas, K

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A72 The use of long gamma nail in fractures of subtrochanteric area by Paraschou, S, Anastasopoulos, H, Chatziliadis, G, Veltsistas, K, Papapanos, A, Alexopoulos, J, Karanikolas, A

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Mitochondrial Uncoupler BAM15 Ameliorates Associated Metabolic PCOS Traits in a Hyperandrogenic PCOS Mouse Model by RODRIGUEZ PARIS, Valentina, ALEXOPOULOS, Stephanie J., HU, Ying, SHAH, Divya P., AFLATOUNIAN, Ali, EDWARDS, Melissa C., BERTOLDO, Michael J., GILCHRIST, Robert B., HOEHN, Kyle L., WALTERS, Kirsty A.

“…Background: Polycystic ovary syndrome (PCOS) is a common endocrine condition characterized by endocrine, reproductive and metabolic abnormalities. There is no…”
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UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells by Schömel, Nina, Gruber, Lisa, Alexopoulos, Stephanie J., Trautmann, Sandra, Olzomer, Ellen M., Byrne, Frances L., Hoehn, Kyle L., Gurke, Robert, Thomas, Dominique, Ferreirós, Nerea, Geisslinger, Gerd, Wegner, Marthe-Susanna

“…The only enzyme in the glycosphingolipid (GSL) metabolic pathway, which produces glucosylceramide (GlcCer) de novo is UDP-glucose ceramide glucosyltransferase…”
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Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice by Chen, Sing-Young, Telfser, Aiden J, Olzomer, Ellen M, Vancuylenberg, Calum S, Zhou, Mingyan, Beretta, Martina, Li, Catherine, Alexopoulos, Stephanie J, Turner, Nigel, Byrne, Frances L, Santos, Webster L, Hoehn, Kyle L

“…Semaglutide is an anti-diabetes and weight loss drug that decreases food intake, slows gastric emptying, and increases insulin secretion. Patients begin…”
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