Search Results - "Alexia Marrel"

Understanding disease symptoms and impacts and producing qualitatively-derived severity stages for MPS IIIA: a mixed methods approach by Lanar, Sally, Parker, Samantha, O'Neill, Cara, Marrel, Alexia, Arnould, Benoit, Héron, Bénédicte, Muschol, Nicole, Wijburg, Frits A, Chakrapani, Anupam, Olivier, Sophie, Aiach, Karen

“…MPS IIIA is a rare, degenerative pediatric genetic disease characterized by symptoms impacting cognition, mobility and behavior; the mean age of death is…”
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Lived experiences of patients with distal renal tubular acidosis treated with ADV7103 and of their caregivers: a qualitative study by Acquadro, Michaël, Marrel, Alexia, Manso-Silván, Maria A, Guittet, Catherine, Joukoff, Sophie, Bertholet-Thomas, Aurélia

“…Consequences of distal renal tubular acidosis (dRTA) on growth, bone and kidney, sometimes associated with hearing loss, may significantly affect quality of…”
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How to address the challenges of evaluating treatment benefits-risks in rare diseases? A convergent mixed methods approach applied within a Merkel cell carcinoma phase 2 clinical trial by Bharmal, Murtuza, Guillemin, Isabelle, Marrel, Alexia, Arnould, Benoit, Lambert, Jérémy, Hennessy, Meliessa, Fofana, Fatoumata

“…Demonstrating treatment benefits within clinical trials in the context of rare diseases is often methodologically and practically challenging. Mixed methods…”
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Psychometric properties of the FACT-M questionnaire in patients with Merkel cell carcinoma by Bharmal, Murtuza, Fofana, Fatoumata, Barbosa, Carla Dias, Williams, Paul, Mahnke, Lisa, Marrel, Alexia, Schlichting, Michael

“…No validated disease-specific questionnaires exist to capture health-related quality of life (HRQoL) in patients with Merkel cell carcinoma (MCC). The…”
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Perceived Unmet Needs in Patients Living With Advanced Bladder Cancer and Their Caregivers: Infodemiology Study Using Data From Social Media in the United States by Renner, Simon, Loussikian, Paul, Foulquié, Pierre, Arnould, Benoit, Marrel, Alexia, Barbier, Valentin, Mebarki, Adel, Schück, Stéphane, Bharmal, Murtuza

“…Background: Locally advanced or metastatic bladder cancer (BC), which is generally termed advanced BC (aBC), has a very poor prognosis, and in addition to its…”
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Correction to: Psychometric properties of the FACT-M questionnaire in patients with Merkel cell carcinoma by Bharmal, Murtuza, Fofana, Fatoumata, Barbosa, Carla Dias, Williams, Paul, Mahnke, Lisa, Marrel, Alexia, Schlichting, Michael

“…Health and Quality of Life Outcomes (2017) 15:247 https://doi.org/10.1186/s12955-017-0815-5 Unfortunately, the original version of this article [1] contained…”
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Patient and Caregiver Perceptions of Advanced Bladder Cancer Systemic Treatments: Infodemiology Study Based on Social Media Data by Renner, Simon, Loussikian, Paul, Foulquié, Pierre, Marrel, Alexia, Barbier, Valentin, Mebarki, Adel, Schück, Stéphane, Bharmal, Murtuza

“…In 2022, it was estimated that more than 80,000 new cases of bladder cancer (BC) were diagnosed in the United States, 12% of which were locally advanced or…”
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When insulin degludec enhances quality of life in patients with type 2 diabetes: a qualitative investigation by Weatherall, James, Polonsky, William H, Lanar, Sally, Knoble, Naomi, Håkan-Bloch, Jonas, Constam, Elisabeth, Philis-Tsimikas, Athena, Marrel, Alexia

“…Anecdotal reports suggest that insulin degludec (IDeg) may offer unique health-related quality of life (HRQoL) benefits. As the nature of these benefits remain…”
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Integrating qualitative interviews in drug development and the use of qualitative evidence in product labelling and health technology assessments: a review by Michel, Anne-Sophie, Kamudoni, Paul, Marrel, Alexia, Adiutori, Rocco, Desvignes-Gleizes, Céline, Lanar, Sally, Schache, Peter, Spies, Erica, Park, Josephine

“…Including qualitative research in clinical trial design is an innovative approach to understanding patients' perspective and incorporate the patient's voice in…”
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Multinational development of a questionnaire assessing patient satisfaction with anticoagulant treatment: the 'Perception of Anticoagulant Treatment Questionnaire' (PACT-Q) by Prins, Martin H, Marrel, Alexia, Carita, Paulo, Anderson, David, Bousser, Marie-Germaine, Crijns, Harry, Consoli, Silla, Arnould, Benoit

“…The side effects and burden of anticoagulant treatments may contribute to poor compliance and consequently to treatment failure. A specific questionnaire is…”
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Interviewing to develop Patient-Reported Outcome (PRO) measures for clinical research: eliciting patients' experience by Brédart, Anne, Marrel, Alexia, Abetz-Webb, Linda, Lasch, Kathy, Acquadro, Catherine

“…Patient-reported outcome (PRO) measures must provide evidence that their development followed a rigorous process for ensuring their content validity. To this…”
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Validation of the Pediatric Narcolepsy Screening Questionnaire (PNSQ): A cross-sectional, observational study by Morris, Susan, Plazzi, Giuseppe, de la Loge, Christine, Marrel, Alexia, Profant, Judi, Steininger, Teresa L., Lin, Junji, Owens, Judith A.

“…This study evaluated psychometric properties of the Pediatric Narcolepsy Screening Questionnaire (PNSQ), developed in response to the difficulty of identifying…”
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Patient (pt) experiences with avelumab in treatment-naive metastatic Merkel cell carcinoma (mMCC): Qualitative interview findings from a registrational clinical trial by Bharmal, Murtuza, Lambert, Jeremy, Russell, Jeffery Scott, Lebbé, Celeste, Chmielowski, Bartosz, Hennessy, Meliessa, Marrel, Alexia, D'Angelo, Sandra P.

“…Abstract only 90 Background: MCC is a rare, aggressive skin cancer with a poor prognosis. Avelumab is the only anti–PD-L1 monoclonal antibody approved for…”
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Comparative effectiveness of avelumab versus chemotherapy in Merkel cell carcinoma: innovative use of patient insights by Bharmal, Murtuza, Marrel, Alexia, Hennessy, Meliessa, Fofana, Fatoumata, Lambert, Jérémy, Arnould, Benoit

“…To assess patient experience with chemotherapy and avelumab in metastatic Merkel cell carcinoma (mMCC). In the JAVELIN Merkel 200 trial,…”
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Patient Experiences with Avelumab in Treatment-Naïve Metastatic Merkel Cell Carcinoma: Longitudinal Qualitative Interview Findings from JAVELIN Merkel 200, a Registrational Clinical Trial by Lambert, Jérémy, Marrel, Alexia, D’Angelo, Sandra P., Burgess, Melissa A., Chmielowski, Bartosz, Fazio, Nicola, Gambichler, Thilo, Grob, Jean-Jacques, Lebbé, Céleste, Robert, Caroline, Russell, Jeffrey, Güzel, Gülseren, Bharmal, Murtuza

“…Background and Objective Avelumab is approved for the treatment of metastatic Merkel cell carcinoma, a rare aggressive skin cancer with a poor prognosis. The…”
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From testimonials to qualitative research embedded in an MPS IIIA observational study by Parker, Samantha, Bekkali, Soraya, Chakrapani, Anupam, Heron, Benedicte, Lavery, Christine, Muschol, Nicole, Roberts, Charlotte, Wijburg, Frits, Arnould, Benoit, Lanar, Sally, Marrel, Alexia, LeMeur, Alice

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How do Clostridium difficile infections affect nurses' everyday hospital work: A qualitative study by Guillemin, Isabelle, Marrel, Alexia, Beriot-Mathiot, Axelle, Doucet, Carole, Kazoglou, Odysseas, Luxemburger, Christine, Reygrobellet, Camille, Arnould, Benoit

“…This qualitative study explored the impact of Clostridium difficile infections on nurses’ everyday work in the hospital. Twelve nurses (six in France and six…”
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Tu2067 The Intestinal Gas Questionnaire (IGQ): A New Instrument for Measuring Gas-Related Symptoms and Their Impact on Daily Life. Results of the Qualitative Analysis by Chassany, Olivier, Tugaut, Beatrice, Marrel, Alexia, Guyonnet, Denis, Arbuckle, Rob, Whorwell, Peter J, Azpiroz, Fernando

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Patients’ Experience and Perception of Hospital-Treated Clostridium difficile Infections: a Qualitative Study by Guillemin, Isabelle, Marrel, Alexia, Lambert, Jérémy, Beriot-Mathiot, Axelle, Doucet, Carole, Kazoglou, Odysseas, Luxemburger, Christine, Reygrobellet, Camille, Arnould, Benoit

“…Background Clostridium difficile is the leading cause of antibiotic-associated diarrhea and an important source of nosocomial infection. Clinical…”
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The community-acquired pneumonia symptom questionnaire: a new, patient-based outcome measure to evaluate symptoms in patients with community-acquired pneumonia by Lamping, Donna L, Schroter, Sara, Marquis, Patrick, Marrel, Alexia, Duprat-Lomon, Isabelle, Sagnier, Pierre-Philippe

“…s: To develop and validate a patient-based outcome measure to evaluate symptoms in patients with community-acquired pneumonia (CAP). A psychometric study…”
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