Search Results - "Alexandrova, G.I."
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Current strategies for the prevention of influenza by the Russian cold-adapted live influenza vaccine among different populations
Published in International Congress series (01-10-2001)“…Trivalent live attenuated influenza vaccine (LIV) prepared from the donor strains A/Len/134/17/57 (H2N2) and B/USSR/60/69 demonstrated safety, immunogenicity,…”
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Genes coding for polymerase proteins are essential for attenuation of the cold-adapted A/Leningrad/134/17/57 (H2N2) influenza virus
Published in International Congress series (01-10-2001)“…Background: The A/Leningrad/134/17/57 (H2N2) (Len/17) cold-adapted (ca) master strain used as a donor of attenuation for preparing live attenuated influenza…”
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Analysis of some factors influencing immunogenicity of live cold-adapted reassortant influenza vaccines
Published in International Congress series (01-06-2004)“…Inability to grow at elevated temperature (temperature sensitivity or ts phenotype) is an important characteristic of wild-type ( wt) viruses. Analysis of our…”
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Reassortment between avian apathogenic and human attenuated cold-adapted viruses as an approach for preparing influenza pandemic vaccines
Published in International Congress series (01-06-2004)“…To prepare candidate influenza pandemic vaccines, we are developing an approach based on reassortment of antigenically appropriate nonpathogenic avian viruses…”
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Live attenuated reassortant influenza vaccine prepared using A/Leningrad/134/17/57 (H2N2) donor strain is genetically stable after replication in children 3-6 years of age
Published in International Congress series (01-10-2001)“…Background: Live influenza A vaccines (LIVs) for adults and children are prepared in Russia by reassorting current epidemic strains with cold-adapted (ca)…”
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Comparison of live attenuated and inactivated influenza vaccines in schoolchildren in Russia: I. Safety and efficacy in two Moscow schools, 1987/88
Published in Vaccine (1993)“…The performance of two doses of cold-adapted live attenuated vaccine versus one dose of whole-virus inactivated vaccine was compared in 8-15-year-old…”
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Laboratory properties of cold-adapted influenza B live vaccine strains developed in the US and USSR, and their B/Ann Arbor/1/86 cold-adapted reassortant vaccine candidates
Published in Vaccine (01-02-1990)“…The adaptation of two influenza B strains (B/Leningrad/14/55 and B/Ann Arbor/1/66) to replication at 25 degrees C is described. Comparison of the two viruses…”
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Study of live recombinant cold-adapted influenza bivalent vaccine of type A for use in children: an epidemiological control trial
Published in Vaccine (01-06-1986)“…Live cold-adapted recombinant bivalent vaccine of influenza type A was studied in a controlled field trial in 1982-1983 among nearly 30,000 children 3-15 years…”
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Evaluation in children of cold-adapted influenza B live attenuated intranasal vaccine prepared by reassortment between wild-type B/Ann Arbor/1/86 and cold-adapted B/Leningrad/14/55 viruses
Published in Vaccine (01-02-1990)“…A reassortant cold-adapted (ca) influenza B experimental live attenuated intranasal vaccine was evaluated for safety and immunogenicity in children by means of…”
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Class-specific antibody responses in school children vaccinated with an A/Brazil/11/78 (H1N1)-like recombinant influenza virus prepared from the A/Leningrad/134/57 paediatric cold-adapted donor strain
Published in Vaccine (01-02-1988)“…Forty-three school children from 8 to 11 years old were vaccinated intranasally with two doses of a paediatric attenuated influenza vaccine developed by…”
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