Search Results - "Alexandre Amaral"
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Mitochondrial dysfunction in fatty acid oxidation disorders: insights from human and animal studies
Published in Bioscience reports (01-02-2016)“…Mitochondrial fatty acid oxidation (FAO) plays a pivotal role in maintaining body energy homoeostasis mainly during catabolic states. Oxidation of fatty acids…”
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The Elusive Structure of Magadiite, Solved by 3D Electron Diffraction and Model Building
Published in Chemistry of materials (11-05-2021)“…In addition to a great swelling ability, layered silicates also allow the functionalization of their interlayer region to form various robust green materials…”
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Proton Migration on Perfect, Vacant, and Doped MgO(001) Surfaces: Role of Dissociation Residual Groups
Published in Journal of physical chemistry. C (27-09-2018)“…Although migration processes on low-coordination surface sites of a magnesium oxide (MgO) surface are important in technological applications including…”
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Encapsulation of essential oils using cinnamic acid grafted chitosan nanogel: Preparation, characterization and antifungal activity
Published in International journal of biological macromolecules (01-01-2021)“…Chemical modifications in the chitosan structure may result in obtaining a new material with improved chemical properties, such as an ability to encapsulate…”
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Rapid and sensitive detection of Candidatus Liberibacter asiaticus by loop mediated isothermal amplification combined with a lateral flow dipstick
Published in BMC microbiology (06-04-2014)“…Citrus Huanglongbing (HLB) is the most devastating bacterial citrus disease worldwide. Three Candidatus Liberibacter species are associated with different…”
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Production and physicochemical properties of fungal chitosans with efficacy to inhibit mycelial growth activity of pathogenic fungi
Published in Carbohydrate research (01-03-2023)“…In order to enable the applicability of chitosan as an antifungal, soil fungi were isolated and identified, then used in its production. Fungal chitosan has…”
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l-Carnitine prevents oxidative stress in striatum of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload
Published in Biochimica et biophysica acta. Molecular basis of disease (01-09-2019)“…The deficiency of the enzyme glutaryl-CoA dehydrogenase leads to predominant accumulation of glutaric acid (GA) in the organism and is known as glutaric…”
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Defining the predicted protein secretome of the fungal wheat leaf pathogen Mycosphaerella graminicola
Published in PloS one (07-12-2012)“…The Dothideomycete fungus Mycosphaerella graminicola is the causal agent of Septoria tritici blotch, a devastating disease of wheat leaves that causes dramatic…”
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Synthesis, cation exchange and dehydration/rehydration of sodium gordaite: NaZn4(OH)6(SO4)Cl·6H2O
Published in Applied clay science (15-09-2017)“…Sodium gordaite (NaG - NaZn4(OH)6(SO4)Cl·6H2O) was synthesized under air and inert atmosphere and characterized by X-ray diffraction (XRD), Fourier transform…”
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10
α-Ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain
Published in Brain research (09-04-2010)“…Abstract Patients affected by maple syrup urine disease (MSUD) present severe neurological symptoms and brain abnormalities, whose pathoiphysiology is poorly…”
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Rapid and sensitive detection of Citrus Bacterial Canker by loop-mediated isothermal amplification combined with simple visual evaluation methods
Published in BMC microbiology (18-06-2010)“…Citrus Bacterial Canker (CBC) is a major, highly contagious disease of citrus plants present in many countries in Asia, Africa and America, but not in the…”
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Recent Advances in the Pathophysiology of Fatty Acid Oxidation Defects: Secondary Alterations of Bioenergetics and Mitochondrial Calcium Homeostasis Caused by the Accumulating Fatty Acids
Published in Frontiers in genetics (27-11-2020)“…Deficiencies of medium-chain acyl-CoA dehydrogenase, mitochondrial trifunctional protein, isolated long-chain 3-hydroxyacyl-CoA dehydrogenase, and very…”
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Deregulation of mitochondrial functions provoked by long‐chain fatty acid accumulating in long‐chain 3‐hydroxyacyl‐CoA dehydrogenase and mitochondrial permeability transition deficiencies in rat heart – mitochondrial permeability transition pore opening as a potential contributing pathomechanism of cardiac alterations in these disorders
Published in The FEBS journal (01-12-2015)“…Mitochondrial trifunctional protein and long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiencies are fatty acid oxidation disorders biochemically characterized…”
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Glutathione ethyl ester supplementation during pancreatic islet isolation improves viability and transplant outcomes in a murine marginal islet mass model
Published in PloS one (12-02-2013)“…The success of pancreatic islet transplantation still faces many challenges, mainly related to cell damage during islet isolation and early post-transplant…”
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Impairment of GABAergic system contributes to epileptogenesis in glutaric acidemia type I
Published in Epilepsia (Copenhagen) (01-10-2017)“…Summary Objectives Glutaric acidemia type I (GA‐I) is an inherited neurometabolic disorder caused by deficiency of glutaryl‐CoA dehydrogenase (GCDH) and…”
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Technological Upgrade of a Vicon RS-EDW Spreader: Development of a Microcontroller for Variable Rate Application
Published in AgriEngineering (01-06-2024)“…Over the last two decades, a considerable amount of equipment has been acquired (spreaders, seeders, sprayers, among others) to respond to the challenges of…”
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Microbiological assessment at slaughter of chicken carcasses from commercial, backyard and semi-backyard production systems
Published in Journal of infection in developing countries (31-12-2021)“…Smaller scale, alternative, chicken production systems are gaining popularity globally. However, this brings public health and market confidence concerns,…”
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In vivo intracerebral administration of L-2-hydroxyglutaric acid provokes oxidative stress and histopathological alterations in striatum and cerebellum of adolescent rats
Published in Free radical biology & medicine (01-06-2015)“…Patients affected by L-2-hydroxyglutaric aciduria (L-2-HGA) are biochemically characterized by elevated L-2-hydroxyglutaric acid (L-2-HG) concentrations in…”
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Sulfite disrupts brain mitochondrial energy homeostasis and induces mitochondrial permeability transition pore opening via thiol group modification
Published in Biochimica et biophysica acta (01-09-2014)“…Sulfite oxidase (SO) deficiency is biochemically characterized by the accumulation of sulfite, thiosulfate and S-sulfocysteine in tissues and biological fluids…”
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Endometriosis and its correlation with carcinoid tumor of the appendix: a systematic review
Published in Minerva obstetrics and gynecology (01-10-2021)“…The prevalence of appendiceal endometriosis ranges from 0.4% to 22%. The carcinoid tumor is the most common neoplasm of the appendix, with incidence ranging…”
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