Search Results - "Alexander Skorokhod"

TERT promoter mutation subtypes and survival in stage I and II melanoma patients by Andrés‐Lencina, Juan J., Rachakonda, Sivaramakrishna, García‐Casado, Zaida, Srinivas, Nalini, Skorokhod, Alexander, Requena, Celia, Soriano, Virtudes, Kumar, Rajiv, Nagore, Eduardo

“…Mutations within the promoter of gene encoding telomerase reverse transcriptase subunit are frequent in many cancers including melanoma. Previously, the TERT…”
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Detection of BRAF V600E mutations in skin metastases of malignant melanoma by monoclonal antibody VE1 by Skorokhod, Alexander, PhD, Capper, David, MD, von Deimling, Andreas, MD, Enk, Alexander, MD, Helmbold, Peter, MD

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Variables that influence BRAF mutation probability: A next-generation sequencing, non-interventional investigation of BRAFV600 mutation status in melanoma by Gaiser, Maria Rita, Skorokhod, Alexander, Gransheier, Diana, Weide, Benjamin, Koch, Winfried, Schif, Birgit, Enk, Alexander, Garbe, Claus, Bauer, Jürgen

“…The incidence of melanoma, particularly in older patients, has steadily increased over the past few decades. Activating mutations of BRAF, the majority…”
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Cleavage of L1 in Exosomes and Apoptotic Membrane Vesicles Released from Ovarian Carcinoma Cells by GUTWEIN, Paul, STOECK, Alexander, ALTEVOGT, Peter, RIEDLE, Svenja, GAST, Daniela, RUNZ, Steffen, CONDON, Thomas P, MARME, Alexander, PHONG, Minh-Chau, LINDERKAMP, Otwin, SKOROKHOD, Alexander

“…Purpose: The L1 adhesion molecule (CD171) is overexpressed in human ovarian and endometrial carcinomas and is associated with bad prognosis. Although expressed…”
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Automated universal BRAF state detection within the activation segment in skin metastases by pyrosequencing-based assay U-BRAF(V600) by Skorokhod, Alexander, Helmbold, Peter, Brors, Benedikt, Schirmacher, Peter, Enk, Alexander, Penzel, Roland

“…Malignant melanoma is a highly-aggressive type of malignancy with considerable metastatic potential and frequent resistance to cytotoxic agents. BRAF mutant…”
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Real-imaging cDNA-AFLP transcript profiling of pancreatic cancer patients: Egr-1 as a potential key regulator of muscle cachexia by Skorokhod, Alexander, Bachmann, Jeannine, Giese, Nathalia A, Martignoni, Marc E, Krakowski-Roosen, Holger

“…Cancer cachexia is a progressive wasting syndrome and the most prevalent characteristic of cancer in patients with advanced pancreatic adenocarcinoma. We…”
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Correction: Automated Universal BRAF State Detection within the Activation Segment in Skin Metastases by Pyrosequencing-Based Assay U-BRAF by Alexander Skorokhod, Peter Helmbold, Benedikt Brors, Peter Schirmacher, Alexander Enk, Roland Penzel

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Universal BRAF State Detection by the Pyrosequencing®-Based U-BRAF(V⁶⁰⁰) Assay by Skorokhod, Alexander

“…Malignant melanoma is a highly aggressive type of malignancy with considerable metastatic potential and frequent resistance to cytotoxic agents. BRAF mutant…”
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Contribution of sponge genes to unravel the genome of the hypothetical ancestor of Metazoa (Urmetazoa) by Müller, W E, Schröder, H C, Skorokhod, A, Bünz, C, Müller, I M, Grebenjuk, V A

“…Recently the term Urmetazoa, as the hypothetical metazoan ancestor, was introduced to highlight the finding that all metazoan phyla including the Porifera…”
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Stimulation of protein (collagen) synthesis in sponge cells by a cardiac myotrophin‐related molecule from Suberites domuncula by C. Schröder, Heinz, Krasko, Anatoli, Batel, Renato, Skorokhod, Alexander, Pahler, Sabine, Kruse, Michael, M. Müller, Isabel, E. G. Müller, Werner

“…ABSTRACT The body wall of sponges (Porifera), the lowest metazoan phylum, is formed by two epithelial cell layers of exopinacocytes and endopinacocytes, both…”
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Molecular evolution of the metazoan extracellular matrix: cloning and expression of structural proteins from the demosponges Suberites domuncula and Geodia cydonium by Schütze, J, Skorokhod, A, Müller, I M, Müller, W E

“…One crucial event during evolution to multicellularity was the development of either direct cell-cell contact or indirect interaction via extracellular matrix…”
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RASSF10 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin but Uncommon in Nevus Cell Nevi by Helmbold, Peter, Richter, Antje M., Walesch, Sara, Skorokhod, Alexander, Marsch, Wolfgang Ch, Enk, Alexander, Dammann, Reinhard H.

“…The Ras association domain family (RASSF) consists of several tumor suppressor genes, which are frequently silenced in human cancers. We analyzed the…”
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Opening a Niche for Therapy: Local Lymphodepletion Helps the Immune System to Fight Melanoma by Mahnke, Karsten, Skorokhod, Alexander, Grabbe, Stefan, Enk, Alexander H.

“…In this issue, Fujiwara et al. report that local ablation of CD4+ T cells in a murine B16 melanoma model, together with concomitant activation of the immune…”
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Correction: Automated Universal BRAF State Detection within the Activation Segment in Skin Metastases by Pyrosequencing-Based Assay U-BRAF V600 by Skorokhod, Alexander, Helmbold, Peter, Brors, Benedikt, Schirmacher, Peter, Enk, Alexander, Penzel, Roland

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Automated Universal BRAF State Detection within the Activation Segment in Skin Metastases by Pyrosequencing-Based Assay U-BRAFV600 by Skorokhod, Alexander, Helmbold, Peter, Brors, Benedikt, Schirmacher, Peter, Enk, Alexander, Penzel, Roland

“…Malignant melanoma is a highly-aggressive type of malignancy with considerable metastatic potential and frequent resistance to cytotoxic agents. BRAF mutant…”
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Correction: Automated Universal BRAF State Detection within the Activation Segment in Skin Metastases by Pyrosequencing-Based Assay U-BRAFV600 by Skorokhod, Alexander, Helmbold, Peter, Brors, Benedikt, Schirmacher, Peter, Enk, Alexander, Penzel, Roland

“…The figures themselves are in correct order. Citation: Skorokhod A, Helmbold P, Brors B, Schirmacher P, Enk A, Penzel R (2013) Correction: Automated Universal…”
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Isolation of a second nonallelic insulin-like growth factor I gene from the salmon genome by Kavsan, V M, Grebenjuk, V A, Koval, A P, Skorokhod, A S, Roberts, Jr, C T, Leroith, D

“…We have characterized a second nonallelic insulin-like growth factor-I (IGF-I) gene in the chum salmon (Oncorhynchus keta) genome. This gene, IGF-I.2, differs…”
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Conservation of the positions of metazoan introns from sponges to humans by Müller, Werner E.G, Böhm, Markus, Grebenjuk, Vladislav A, Skorokhod, Alexander, Müller, Isabel M, Gamulin, Vera

“…Sponges (phylum Porifera) are the phylogenetic oldest Metazoa still extant. They can be considered as reference animals (Urmetazoa) for the understanding of…”
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Histocompatibility reaction in tissue and cells of the marine sponge Suberites domuncula in vitro and in vivo: central role of the allograft inflammatory factor 1 by Müller, Werner E G, Krasko, Anatoli, Skorokhod, Alexander, Bünz, Christina, Grebenjuk, Vladislav A, Steffen, Renate, Batel, Renato, Schröder, Heinz C

“…Sponges (Porifera) are the phylogenetically oldest still extant metazoan phylum. Recently elements of their immune system have been cloned and analyzed,…”
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Multiple Ig-like featuring genes divergent within and among individuals of the marine sponge Geodia cydonium by Pancer, Zeev, Skorokhod, Alexander, Blumbach, Barbara, Müller, Werner E.G

“…The receptor tyrosine kinase of the marine sponge Geodia cydonium features two extracellular Ig-like domains in which we recently documented RT-PCR…”
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