Search Results - "Alexander Schubert, Gerrit"
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Acute changes of pro-inflammatory markers and corticosterone in experimental subarachnoid haemorrhage: A prerequisite for severity assessment
Published in PloS one (30-07-2019)“…Many details of the pathophysiology of subarachnoid haemorrhage (SAH) still remain unknown, making animal experiments an indispensable tool for assessment of…”
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The oxygen reactivity index indicates disturbed local perfusion regulation after aneurysmal subarachnoid hemorrhage: an observational cohort study
Published in Critical care (London, England) (13-06-2023)“…Cerebral autoregulation (CA) can be impaired in patients with delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). The Pressure…”
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Levels of bioactive adrenomedullin in plasma and cerebrospinal fluid in relation to delayed cerebral ischemia in patients after aneurysmal subarachnoid hemorrhage: A prospective observational study
Published in Journal of the neurological sciences (15-08-2021)“…Adrenomedullin (ADM) has been identified as a promising biomarker of mortality and outcome in sepsis, heart failure and after major surgery. A recently…”
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CT perfusion illustrated reversal of uncal herniation after placement of an external ventricular drain
Published in Interdisciplinary neurosurgery : Advanced techniques and case management (01-12-2015)“…Abstract Compression of the PCA in the context of uncal herniation is usually deducted in retrospect only with presence of a demarcated infarction in the…”
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Anticoagulation Therapy After Surgical Treatment of Spinal Dural Arteriovenous Fistula. Effectiveness and Long-Term Outcome Analysis
Published in World neurosurgery (01-06-2018)“…Effectiveness and safety of anticoagulation therapy (AC) after treatment of spinal dural arteriovenous fistula (sdAVF) are still inadequately discussed in the…”
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Endovascular Rescue Treatment for Delayed Cerebral Ischemia After Subarachnoid Hemorrhage Is Safe and Effective
Published in Frontiers in neurology (21-02-2019)“…The implementation of rescue efforts for delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage remains largely empirical for a lack of supporting…”
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Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis
Published in PloS one (04-10-2018)“…Impairment of neurovascular coupling (NVC) was recently reported in the context of subarachnoid hemorrhage and may correlate with disease severity and outcome…”
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Changes in endogenous daytime melatonin levels after aneurysmal subarachnoid hemorrhage – Preliminary findings from an observational cohort study
Published in Clinical neurology and neurosurgery (01-09-2021)“…Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include…”
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Effect of isolated intracranial hypertension on cerebral perfusion within the phase of primary disturbances after subarachnoid hemorrhage in rats
Published in Frontiers in cellular neuroscience (12-07-2023)“…Elevated intracranial pressure (ICP) and blood components are the main trigger factors starting the complex pathophysiological cascade following subarachnoid…”
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Value of Glycemic Indices for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage: A Retrospective Single-Center Study
Published in Brain sciences (01-09-2024)“…Delayed cerebral ischemia (DCI) is a severe complication following aneurysmal subarachnoid hemorrhage (aSAH), linked to poor functional outcomes and prolonged…”
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Risk Profile In Extracranial/Intracranial Bypass Surgery—The Role of Antiplatelet Agents, Disease Pathology, and Surgical Technique In 168 Direct Revascularization Procedures
Published in World neurosurgery (01-11-2014)“…Objective Cerebral revascularization procedures are a treatment option in moyamoya disease patients, but recent studies failed to show an immediate benefit in…”
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Elevated concentrations of macrophage migration inhibitory factor in serum and cerebral microdialysate are associated with delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage
Published in Frontiers in neurology (13-01-2023)“…Inflammation is increasingly recognized to be involved in the pathophysiology of aneurysmal subarachnoid hemorrhage (aSAH) and may increase the susceptibility…”
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Cortical volume reductions as a sign of secondary cerebral and cerebellar impairment in patients with degenerative cervical myelopathy
Published in NeuroImage clinical (01-01-2021)“…•Degenerative cervical myelopathy is the most common cause of chronic impairment of the spinal cord.•MRI-based anatomical assessment of cerebral and cerebellar…”
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Modulation of Cav2.3 channels by unconjugated bilirubin (UCB) – Candidate mechanism for UCB-induced neuromodulation and neurotoxicity
Published in Molecular and cellular neuroscience (01-04-2019)“…Elevated levels of unbound unconjugated bilirubin (UCB) can lead to bilirubin encephalopathy and kernicterus. In spite of a large number of studies…”
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Non-invasive Assessment of Neurovascular Coupling After Aneurysmal Subarachnoid Hemorrhage: A Prospective Observational Trial Using Retinal Vessel Analysis
Published in Frontiers in neurology (14-06-2021)“…Objective: Delayed cerebral ischemia (DCI) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) and can lead to infarction and poor…”
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Retinal Vessel Responses to Flicker Stimulation Are Impaired in Cav2.3-Deficient Mice—An in-vivo Evaluation Using Retinal Vessel Analysis (RVA)
Published in Frontiers in neurology (13-04-2021)“…Objective: Metabolic demand increases with neuronal activity and adequate energy supply is ensured by neurovascular coupling (NVC). Impairments of NVC have…”
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Retinal Vessel Analysis (RVA) in the Context of Subarachnoid Hemorrhage - A Proof of Concept Study
Published in PloS one (07-07-2016)“…Timely detection of impending delayed cerebral ischemia after subarachnoid hemorrhage (SAH) is essential to improve outcome, but poses a diagnostic challenge…”
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Systemic and Cerebral Concentration of Nimodipine During Established and Experimental Vasospasm Treatment
Published in World neurosurgery (01-06-2017)“…Abstract Background Oral nimodipine is an established prophylactic agent for cerebral vasospasm after subarachnoid hemorrhage (SAH). In highly selected cases,…”
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Cerebral blood flow changes in acute subarachnoid hemorrhage
Published in Frontiers in bioscience (01-01-2008)“…Delayed vasospasm and secondary injury due to ischemia occur frequently in the setting of subarachnoid hemorrhage (SAH), and these changes have been well…”
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