Search Results - "Alexander, William H"

Frontal cortex function as derived from hierarchical predictive coding by Alexander, William H., Brown, Joshua W.

“…The frontal lobes are essential for human volition and goal-directed behavior, yet their function remains unclear. While various models have highlighted…”
Get full text

Hierarchical Error Representation: A Computational Model of Anterior Cingulate and Dorsolateral Prefrontal Cortex by Alexander, William H, Brown, Joshua W

“…Anterior cingulate and dorsolateral prefrontal cortex (ACC and dlPFC, respectively) are core components of the cognitive control network. Activation of these…”
Get more information

Degeneracy measures in biologically plausible random Boolean networks by Kocaoglu, Basak, Alexander, William H

“…Degeneracy-the ability of structurally different elements to perform similar functions-is a property of many biological systems. Highly degenerate systems show…”
Get full text

The Role of the Anterior Cingulate Cortex in Prediction Error and Signaling Surprise by Alexander, William H., Brown, Joshua W.

“…In the past two decades, reinforcement learning (RL) has become a popular framework for understanding brain function. A key component of RL models, prediction…”
Get full text

Distinct Regions within Medial Prefrontal Cortex Process Pain and Cognition by Jahn, Andrew, Nee, Derek Evan, Alexander, William H, Brown, Joshua W

“…Neuroimaging studies of the medial prefrontal cortex (mPFC) suggest that the dorsal anterior cingulate cortex (dACC) region is responsive to a wide variety of…”
Get full text

Computational Models of Anterior Cingulate Cortex: At the Crossroads between Prediction and Effort by Vassena, Eliana, Holroyd, Clay B, Alexander, William H

“…In the last two decades the anterior cingulate cortex (ACC) has become one of the most investigated areas of the brain. Extensive neuroimaging evidence…”
Get full text

Multisensory integration in humans with spinal cord injury by Vastano, Roberta, Costantini, Marcello, Alexander, William H., Widerstrom-Noga, Eva

“…Although multisensory integration (MSI) has been extensively studied, the underlying mechanisms remain a topic of ongoing debate. Here we investigate these…”
Get full text

Interactions of Medial and Lateral Prefrontal Cortex in Hierarchical Predictive Coding by Alexander, William H, Womelsdorf, Thilo

“…Cognitive control and decision-making rely on the interplay of medial and lateral prefrontal cortex (mPFC/lPFC), particularly for circumstances in which…”
Get full text

Computational Models of Performance Monitoring and Cognitive Control by Alexander, William H., Brown, Joshua W.

“…The medial prefrontal cortex (mPFC) has been the subject of intense interest as a locus of cognitive control. Several computational models have been proposed…”
Get full text

Independent and interacting value systems for reward and information in the human brain by Cogliati Dezza, Irene, Cleeremans, Axel, Alexander, William H

“…Theories of prefrontal cortex (PFC) as optimizing value have been widely deployed to explain its activity in a diverse range of contexts, with substantial…”
Get full text

A general role for medial prefrontal cortex in event prediction by Alexander, William H, Brown, Joshua W

“…A recent computational neural model of medial prefrontal cortex (mPFC), namely the predicted response-outcome (PRO) model (Alexander and Brown, 2011), suggests…”
Get full text

Medial prefrontal cortex as an action-outcome predictor by Brown, Joshua W, Alexander, William H

“…The authors present a computational model based on standard learning rules that can simulate and account for a large range of known effects in the medial…”
Get full text

Hyperbolically discounted temporal difference learning by Alexander, William H, Brown, Joshua W

“…Hyperbolic discounting of future outcomes is widely observed to underlie choice behavior in animals. Additionally, recent studies (Kobayashi & Schultz, 2008)…”
Get more information

Predicting Motivation: Computational Models of PFC Can Explain Neural Coding of Motivation and Effort-based Decision-making in Health and Disease by Vassena, Eliana, Deraeve, James, Alexander, William H

“…Human behavior is strongly driven by the pursuit of rewards. In daily life, however, benefits mostly come at a cost, often requiring that effort be exerted to…”
Get more information

Dissociation and integration of outcome and state uncertainty signals in cognitive control by Alexander, William H., Deraeve, James, Vassena, Eliana

“…Signals related to uncertainty are frequently observed in regions of the cognitive control network, including anterior cingulate/medial prefrontal cortex…”
Get full text

Reward salience and risk aversion underlie differential ACC activity in substance dependence by Alexander, William H, Fukunaga, Rena, Finn, Peter, Brown, Joshua W

“…The medial prefrontal cortex, especially the dorsal anterior cingulate cortex (ACC), has long been implicated in cognitive control and error processing…”
Get full text

Task-specific prioritization of reward and effort information: Novel insights from behavior and computational modeling by Vassena, Eliana, Deraeve, James, Alexander, William H.

“…Efficient integration of environmental information is critical in goal-directed behavior. Motivational information regarding potential rewards and costs (such…”
Get full text

Discounting of reward sequences: a test of competing formal models of hyperbolic discounting by Zarr, Noah, Alexander, William H, Brown, Joshua W

“…Humans are known to discount future rewards hyperbolically in time. Nevertheless, a formal recursive model of hyperbolic discounting has been elusive until…”
Get full text

Foraging Value, Risk Avoidance, and Multiple Control Signals: How the Anterior Cingulate Cortex Controls Value-based Decision-making by Brown, Joshua W, Alexander, William H

“…Recent work on the role of the ACC in cognition has focused on choice difficulty, action value, risk avoidance, conflict resolution, and the value of exerting…”
Get more information

Surprise, value and control in anterior cingulate cortex during speeded decision-making by Vassena, Eliana, Deraeve, James, Alexander, William H.

“…Activity in the dorsal anterior cingulate cortex (dACC) is observed across a variety of contexts, and its function remains intensely debated in the field of…”
Get full text