Search Results - "Alexander, Thomas"

Human Immunodeficiency Virus Diagnostic Testing: 30 Years of Evolution by Alexander, Thomas S

“…A concern during the early AIDS epidemic was the lack of a test to identify individuals who carried the virus. The first HIV antibody test, developed in 1985,…”
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Deep learning in cancer pathology: a new generation of clinical biomarkers by Echle, Amelie, Rindtorff, Niklas Timon, Brinker, Titus Josef, Luedde, Tom, Pearson, Alexander Thomas, Kather, Jakob Nikolas

“…Clinical workflows in oncology rely on predictive and prognostic molecular biomarkers. However, the growing number of these complex biomarkers tends to…”
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Incidence of Sudden Sensorineural Hearing Loss by Alexander, Thomas H, Harris, Jeffrey P

“…OBJECTIVERecent data regarding the incidence of sudden sensorineural hearing loss (SSNHL) in the United States is lacking. The objective of this study was to…”
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Intentions to use bike-sharing for holiday cycling: An application of the Theory of Planned Behavior by Kaplan, Sigal, Manca, Francesco, Nielsen, Thomas Alexander Sick, Prato, Carlo Giacomo

“…This study explored the behavioral factors underlying tourist intentions to use urban bike-sharing for cycling while on holiday. The analytical framework…”
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On progress and reason: stories of gods, animals and humans by Thomas, Alexander

“…PurposeWhile transhumanists and posthumanists understand the human condition as mutable, for transhumanists, this represents the possibility for enhancement,…”
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Epigenetic small molecule modulators of histone and DNA methylation by Hauser, Alexander-Thomas, Robaa, Dina, Jung, Manfred

“…•Histone and DNA methylation are associated with many diseases, esp. cancer.•Inhibitors of DNA methyltransferases are approved leukemia drugs.•Inhibitors of…”
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Evaluation of Therapeutic Targets in Histological Subtypes of Bladder Cancer by Wucherpfennig, Sophie, Rose, Michael, Maurer, Angela, Cassataro, Maria Angela, Seillier, Lancelot, Morsch, Ronja, Hammad, Ehab, Baldia, Philipp Heinrich, Ecke, Thorsten H, Vögeli, Thomas-Alexander, Knüchel, Ruth, Gaisa, Nadine T

“…Histologically, bladder cancer is a heterogeneous group comprising urothelial carcinoma (UC), squamous cell carcinoma, adenocarcinomas (ACs), urachal…”
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Mixed Phenotype Acute Leukemia: Current Approaches to Diagnosis and Treatment by Alexander, Thomas B., Orgel, Etan

“…Purpose of Review Mixed phenotype acute leukemia (MPAL) is a rare subtype of acute leukemia with features of both acute lymphoblastic leukemia (ALL) and acute…”
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Photopolymerizable gelatin and hyaluronic acid for stereolithographic 3D bioprinting of tissue‐engineered cartilage by Lam, Tobias, Dehne, Tilo, Krüger, Jan Philipp, Hondke, Sylvia, Endres, Michaela, Thomas, Alexander, Lauster, Roland, Sittinger, Michael, Kloke, Lutz

“…To create artificial cartilage in vitro, mimicking the function of native extracellular matrix (ECM) and morphological cartilage‐like shape is essential. The…”
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Unusual mammalian usage of TGA stop codons reveals that sequence conservation need not imply purifying selection by Ho, Alexander Thomas, Hurst, Laurence Daniel

“…The assumption that conservation of sequence implies the action of purifying selection is central to diverse methodologies to infer functional importance…”
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A Methylation-Based Reclassification of Bladder Cancer Based on Immune Cell Genes by Luo, Qizhan, Vögeli, Thomas-Alexander

“…Background: Bladder cancer is highly related to immune cell infiltration. This study aimed to develop a new classification of BC molecular subtypes based on…”
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Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing by Valletta, Simona, Thomas, Alexander, Meng, Yiran, Ren, Xiying, Drissen, Roy, Sengül, Hilal, Di Genua, Cristina, Nerlov, Claus

“…Hematopoietic ageing involves declining erythropoiesis and lymphopoiesis, leading to frequent anaemia and decreased adaptive immunity. How intrinsic changes to…”
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Therapeutic implications of PD-L1 expression in bladder cancer with squamous differentiation by Morsch, Ronja, Rose, Michael, Maurer, Angela, Cassataro, Maria Angela, Braunschweig, Till, Knüchel, Ruth, Vögeli, Thomas-Alexander, Ecke, Thorsten, Eckstein, Markus, Weyerer, Veronika, Esposito, Irene, Ackermann, Maximilian, Niegisch, Günter, Gaisa, Nadine T

“…Immune checkpoint inhibitors (ICI) are an integral part of bladder cancer therapy, however, the relevance of ICI treatment for mixed and pure squamous cell…”
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Towards isolated attosecond electron bunches using ultrashort-pulse laser-solid interactions by Lin, Jinpu, Batson, Thomas, Nees, John, Thomas, Alexander G. R., Krushelnick, Karl

“…We investigate MeV-level attosecond electron bunches from ultrashort-pulse laser-solid interactions through similarities between experimental and simulated…”
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Bioprinting Perfusion-Enabled Liver Equivalents for Advanced Organ-on-a-Chip Applications by Grix, Tobias, Ruppelt, Alicia, Thomas, Alexander, Amler, Anna-Klara, Noichl, Benjamin P, Lauster, Roland, Kloke, Lutz

“…Many tissue models have been developed to mimic liver-specific functions for metabolic and toxin conversion in in vitro assays. Most models represent a 2D…”
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Mapping spatio-temporal patterns and detecting the factors of traffic congestion with multi-source data fusion and mining techniques by Song, Jinchao, Zhao, Chunli, Zhong, Shaopeng, Nielsen, Thomas Alexander Sick, Prishchepov, Alexander V.

“…The study focuses on mapping spatiotemporal patterns and detecting the potential drivers of traffic congestion with multi-source data. First, based on…”
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EGFR activity addiction facilitates anti-ERBB based combination treatment of squamous bladder cancer by Rose, Michael, Maurer, Angela, Wirtz, Julia, Bleilevens, Andreas, Waldmann, Tanja, Wenz, Maximilian, Eyll, Marie, Geelvink, Mirja, Gereitzig, Melanie, Rüchel, Nadine, Denecke, Bernd, Eltze, Elke, Herrmann, Edwin, Toma, Marieta, Horst, David, Grimm, Tobias, Denzinger, Stefan, Ecke, Thorsten, Vögeli, Thomas Alexander, Knuechel, Ruth, Maurer, Jochen, Gaisa, Nadine T.

“…Recent findings suggested a benefit of anti-EGFR therapy for basal-like muscle-invasive bladder cancer (MIBC). However, the impact on bladder cancer with…”
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High rate of stone-related complications after stapling the cystic duct during laparoscopic cholecystectomy—an underrecognized risk by Thomas, Alexander S., Gleit, Zachary, Younan, Stephanie, Genkinger, Jeanine, Kluger, Michael D.

“…Background Laparoscopic staplers (LS) have been suggested as a safe alternative to metal clips in laparoscopic cholecystectomy when the cystic duct is too…”
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Pseudoparalysis: a systematic review of term definitions, treatment approaches, and outcomes of management techniques by Tokish, John M., Alexander, Thomas C., Kissenberth, Michael J., Hawkins, Richard J.

“…Pseudoparalysis remains one of the most challenging conditions in shoulder surgery. Long thought of as an unsolvable problem, recent advances in surgical…”
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Ice-sheet collapse and sea-level rise at the Bølling warming 14,600 years ago by Deschamps, Pierre, Durand, Nicolas, Bard, Edouard, Hamelin, Bruno, Camoin, Gilbert, Thomas, Alexander L., Henderson, Gideon M., Okuno, Jun'ichi, Yokoyama, Yusuke

“…Past sea-level records provide invaluable information about the response of ice sheets to climate forcing. Some such records suggest that the last deglaciation…”
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