Search Results - "Alexander, Neal DE"
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Strategies for control of trachoma: observational study with quantitative PCR
Published in The Lancet (British edition) (19-07-2003)“…Antibiotics are an important part of WHO's strategy to eliminate trachoma as a blinding disease by 2020. At present, who needs to be treated is unclear. We…”
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Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study
Published in The Lancet (British edition) (09-04-2005)“…Community-wide mass antibiotic treatment is a central component of trachoma control. The optimum frequency and duration of treatment are unknown. We measured…”
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3
Sample size calculations for skewed distributions
Published in BMC medical research methodology (02-04-2015)“…Sample size calculations should correspond to the intended method of analysis. Nevertheless, for non-normal distributions, they are often done on the basis of…”
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Defining Seropositivity Thresholds for Use in Trachoma Elimination Studies
Published in PLoS neglected tropical diseases (18-01-2017)“…Efforts are underway to eliminate trachoma as a public health problem by 2020. Programmatic guidelines are based on clinical signs that correlate poorly with…”
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Mass Treatment with Single-Dose Azithromycin for Trachoma
Published in The New England journal of medicine (04-11-2004)“…Trachoma, an important cause of blindness, is caused by infection with Chlamydia trachomatis . In a Tanzanian community in which trachoma was endemic, the…”
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Two Doses of Azithromycin to Eliminate Trachoma in a Tanzanian Community
Published in The New England journal of medicine (24-04-2008)“…These authors found that one or two rounds of high-coverage mass treatment with azithromycin may be sufficient to eliminate ocular C. trachomatis in…”
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Profound and sustained reduction in Chlamydia trachomatis in The Gambia: a five-year longitudinal study of trachoma endemic communities
Published in PLoS neglected tropical diseases (05-10-2010)“…The elimination of blinding trachoma focuses on controlling Chlamydia trachomatis infection through mass antibiotic treatment and measures to limit…”
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Mass Treatment to Eliminate Filariasis in Papua New Guinea
Published in The New England journal of medicine (05-12-2002)“…In Papua New Guinea, approximately 2500 residents participated in a prospective, four-year study of the effects of a single dose of antifilarial drugs given…”
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Reduction in acute filariasis morbidity during a mass drug administration trial to eliminate lymphatic filariasis in Papua New Guinea
Published in PLoS neglected tropical diseases (01-07-2011)“…Acute painful swelling of the extremities and scrotum are debilitating clinical manifestations of Wuchereria bancrofti infection. The ongoing global program to…”
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Randomised community-based trial of annual single-dose diethylcarbamazine with or without ivermectin against Wuchereria bancrofti infection in human beings and mosquitoes
Published in The Lancet (British edition) (17-01-1998)“…WHO has targeted lymphatic filariasis for elimination. Studies of vector-parasite relations of Wuchereria bancrofti suggest that a reduction in the…”
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