Search Results - "Alexander, Marcus"

Navigating the new landscape of second‐line treatment in advanced hepatocellular carcinoma by Rimassa, Lorenza, Wörns, Marcus‐Alexander

“…Sorafenib and lenvatinib are approved for first‐line treatment of patients with advanced hepatocellular carcinoma (HCC), and the efficacy of atezolizumab plus…”
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HCC therapies—lessons learned by Wörns, Marcus-Alexander, Galle, Peter Robert

“…Advancing the field of therapeutics for hepatocellular carcinoma has been far more challenging than initially anticipated; sorafenib is the only approved…”
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Predictors of advanced fibrosis in non‐cirrhotic non‐alcoholic fatty liver disease in Germany by Labenz, Christian, Huber, Yvonne, Kalliga, Eva, Nagel, Michael, Ruckes, Christian, Straub, Beate K., Galle, Peter R., Wörns, Marcus‐Alexander, Anstee, Quentin M., Schuppan, Detlef, Schattenberg, Jörn M.

“…Summary Background Advanced fibrosis has been established as the most important predictor of overall mortality in patients with non‐alcoholic fatty liver…”
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Quantitative Particle Uptake by Cells as Analyzed by Different Methods by Ashraf, Sumaira, Hassan Said, Alaa, Hartmann, Raimo, Assmann, Marcus‐Alexander, Feliu, Neus, Lenz, Peter, Parak, Wolfgang J.

“…There is a large number of two‐dimensional static in vitro studies about the uptake of colloidal nano‐ and microparticles, which has been published in the last…”
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Preliminary experience on safety of regorafenib after sorafenib failure in recurrent hepatocellular carcinoma after liver transplantation by Iavarone, Massimo, Invernizzi, Federica, Czauderna, Carolin, Sanduzzi‐Zamparelli, Marco, Bhoori, Sherrie, Amaddeo, Giuliana, Manini, Matteo A., López, Miguel F., Anders, Margarita, Pinter, Matthias, Rodríguez, Maria J. B., Cristóbal, Mario R., Soteras, Gabriel A., Piñero, Federico, Villadsen, Gerda E., Weinmann, Arndt, Crespo, Gonzalo, Mazzaferro, Vincenzo, Regnault, Helene, Giorgio, Massimo De, González‐Diéguez, Maria L., Donato, Maria F., Varela, Maria, Wörns, Marcus‐Alexander, Bruix, Jordi, Lampertico, Pietro, Reig, Maria

“…Regorafenib is one option for second‐line treatment of hepatocellular carcinoma (HCC), improving overall survival (OS) of sorafenib‐tolerant patients who…”
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Hydrogels as Emerging Materials for Cornea Wound Healing by Khosravimelal, Sadjad, Mobaraki, Mohammadmahdi, Eftekhari, Samane, Ahearne, Mark, Seifalian, Alexander Marcus, Gholipourmalekabadi, Mazaher

“…Hydrogel biomaterials have many favorable characteristics including tuneable mechanical behavior, cytocompatibility, optical properties suitable for…”
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Letter: diabetes mellitus increases the risk of hepatic encephalopathy in patients with cirrhosis—authors’ reply by Labenz, Christian, Wörns, Marcus‐Alexander

“…LINKED CONTENT This article is linked to Labenz et al and Liu et al papers. To view these articles, visit https://doi.org/10.1111/apt.15915 and…”
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Raised serum Interleukin‐6 identifies patients with liver cirrhosis at high risk for overt hepatic encephalopathy by Labenz, Christian, Toenges, Gerrit, Huber, Yvonne, Nagel, Michael, Marquardt, Jens U., Schattenberg, Jörn M., Galle, Peter R., Labenz, Joachim, Wörns, Marcus‐Alexander

“…Summary Background Systemic inflammation is a driving force for the development of hepatic encephalopathy and recent studies demonstrated that elevated…”
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How COVID-19 kick-started online learning in medical education-The DigiMed study by Stoehr, Fabian, Müller, Lukas, Brady, Adrian, Trilla, Antoni, Mähringer-Kunz, Aline, Hahn, Felix, Düber, Christoph, Becker, Nicole, Wörns, Marcus-Alexander, Chapiro, Julius, Hinrichs, Jan Bernd, Akata, Deniz, Ellmann, Stephan, Huisman, Merel, Koff, David, Brinkmann, Sebastian, Bamberg, Fabian, Zimmermann, Oscar, Traikova, Nikoleta I, Marquardt, Jens U, Chang, D-H, Rengier, Fabian, Auer, Timo A, Emrich, Tilman, Muehler, Felix, Schmidberger, Heinz, Baeßler, Bettina, Dos Santos, Daniel Pinto, Kloeckner, Roman

“…The coronavirus disease 2019 (COVID-19) pandemic led to far-reaching restrictions of social and professional life, affecting societies all over the world. To…”
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Natural polymers in wound healing: From academic studies to commercial products by Tavakoli, Mohamadreza, Labbaf, Sheyda, Mirhaj, Marjan, Salehi, Saeideh, Seifalian, Alexander Marcus, Firuzeh, Mahboubeh

“…Natural biopolymers (carbohydrates and proteins) are the family of natural polymers that are widely used in wound healing. This is due to their…”
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Proton pump inhibitors increase risk of bone fractures in men with cirrhosis: a population‐based study by Labenz, Christian, Wörns, Marcus‐Alexander, Adarkwah, Charles C., Galle, Peter R., Schattenberg, Jörn M., Kostev, Karel

“…Summary Background Bone fractures are a frequent complication in patients with cirrhosis. Proton pump inhibitors (PPIs) are among the most frequently…”
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Context Modularity of Human Altruism by Alexander, Marcus, Christia, Fotini

“…Whereas altruism drives the evolution of human cooperation, ethno-religious diversity has been considered to obstruct it, leading to poverty, corruption, and…”
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Efficacy and safety of glecaprevir/pibrentasvir in renally impaired patients with chronic HCV infection by Lawitz, Eric, Flisiak, Robert, Abunimeh, Manal, Sise, Meghan E., Park, Jun Y., Kaskas, Marwan, Bruchfeld, Annette, Wörns, Marcus‐Alexander, Aglitti, Andrea, Zamor, Philippe J., Xue, Zhenyi, Schnell, Gretja, Jalundhwala, Yash J., Porcalla, Ariel, Mensa, Federico J., Persico, Marcello

“…Background and Aims Chronic hepatitis C virus (HCV) infection increases the risk of incident chronic kidney disease (CKD) and progression to end‐stage renal…”
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Immune oncology in hepatocellular carcinoma—hype and hope by Wörns, Marcus-Alexander, Galle, Peter R

“…Thus, the definition of a first and so far only standard of care for hepatocellular carcinoma, a milestone 10 years ago, was followed by gridlock; no standard…”
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Association between diabetes mellitus and hepatic encephalopathy in patients with cirrhosis by Labenz, Christian, Nagel, Michael, Kremer, Wolfgang M., Hilscher, Max, Schilling, Caroline A., Toenges, Gerrit, Kuchen, Robert, Schattenberg, Jörn M., Galle, Peter R., Wörns, Marcus‐Alexander

“…Summary Background Diabetes mellitus may lead to increased serum ammonia and systemic inflammation thereby promoting hepatic encephalopathy (HE). Aim To…”
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Structured Early detection of Asymptomatic Liver Cirrhosis: Results of the population-based liver screening program SEAL by Labenz, Christian, Arslanow, Anita, Nguyen-Tat, Marc, Nagel, Michael, Wörns, Marcus-Alexander, Reichert, Matthias Christian, Heil, Franz Josef, Mainz, Dagmar, Zimper, Gundula, Römer, Barbara, Binder, Harald, Farin-Glattacker, Erik, Fichtner, Urs, Graf, Erika, Stelzer, Dominikus, Van Ewijk, Reyn, Ortner, Julia, Velthuis, Louis, Lammert, Frank, Galle, Peter R.

“…Detection of patients with early cirrhosis is of importance to prevent the occurrence of complications and improve prognosis. The SEAL program aimed at…”
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Elevated serum levels of methylglyoxal are associated with impaired liver function in patients with liver cirrhosis by Michel, Maurice, Hess, Cornelius, Kaps, Leonard, Kremer, Wolfgang M., Hilscher, Max, Galle, Peter R., Moehler, Markus, Schattenberg, Jörn M., Wörns, Marcus-Alexander, Labenz, Christian, Nagel, Michael

“…Methylglyoxal (MGO) is a highly reactive dicarbonyl species that forms advanced glycation end products (AGEs). The binding of these AGEs to their receptor…”
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Proton pump inhibitor use is associated with a variety of infections in patients with liver cirrhosis by Labenz, Christian, Kostev, Karel, Galle, Peter R., Wörns, Marcus-Alexander, Labenz, Joachim, Tanislav, Christian, Adarkwah, Charles Christian

“…There is evidence that intake of proton pump inhibitors (PPI) increases the risk for spontaneous bacterial peritonitis (SBP) in patients with liver cirrhosis…”
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Transient binding of dynein controls bidirectional long-range motility of early endosomes by Schuster, Martin, Lipowsky, Reinhard, Assmann, Marcus-Alexander, Lenz, Peter, Steinberg, Gero

“…In many cell types, bidirectional long-range endosome transport is mediated by the opposing motor proteins dynein and kinesin-3. Here we use a fungal model…”
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Clinical Frailty Scale for risk stratification in patients with SARS-CoV-2 infection by Labenz, Christian, Kremer, Wolfgang M., Schattenberg, Jörn M., Wörns, Marcus-Alexander, Toenges, Gerrit, Weinmann, Arndt, Galle, Peter R., Sprinzl, Martin F.

“…Predictive factors for adverse outcomes in patients with COVID-19 are urgently needed. Data related to the applicability of the Clinical Frailty Scale (CFS)…”
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