Search Results - "Alexander, LN"

A mood state‐specific interaction between kynurenine metabolism and inflammation is present in bipolar disorder by Ameele, Seline, Nuijs, Alexander LN, Lai, Foon Yin, Schuermans, Jeroen, Verkerk, Robert, Diermen, Linda, Coppens, Violette, Fransen, Erik, Boer, Peter, Timmers, Maarten, Sabbe, Bernard, Morrens, Manuel

“…Objectives Cytokines are thought to contribute to the pathogenesis of psychiatric symptoms by kynurenine pathway activation. Kynurenine metabolites affect…”
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Mass spectrometric strategies for the investigation of biomarkers of illicit drug use in wastewater by Hernández, Félix, Castiglioni, Sara, Covaci, Adrian, de Voogt, Pim, Emke, Erik, Kasprzyk‐Hordern, Barbara, Ort, Christoph, Reid, Malcolm, Sancho, Juan V., Thomas, Kevin V., van Nuijs, Alexander L.N., Zuccato, Ettore, Bijlsma, Lubertus

“…The analysis of illicit drugs in urban wastewater is the basis of wastewater‐based epidemiology (WBE), and has received much scientific attention because the…”
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Illicit drug consumption estimations derived from wastewater analysis: A critical review by van Nuijs, Alexander L.N., Castiglioni, Sara, Tarcomnicu, Isabela, Postigo, Cristina, de Alda, Miren Lopez, Neels, Hugo, Zuccato, Ettore, Barcelo, Damia, Covaci, Adrian

“…The consumption of illicit drugs causes indisputable societal and economic damage. Therefore it is necessary to know their usage levels and trends for…”
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Comparing illicit drug use in 19 European cities through sewage analysis by Thomas, Kevin V., Bijlsma, Lubertus, Castiglioni, Sara, Covaci, Adrian, Emke, Erik, Grabic, Roman, Hernández, Félix, Karolak, Sara, Kasprzyk-Hordern, Barbara, Lindberg, Richard H., Lopez de Alda, Miren, Meierjohann, Axel, Ort, Christoph, Pico, Yolanda, Quintana, José B., Reid, Malcolm, Rieckermann, Jörg, Terzic, Senka, van Nuijs, Alexander L.N., de Voogt, Pim

“…The analysis of sewage for urinary biomarkers of illicit drugs is a promising and complementary approach for estimating the use of these substances in the…”
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Drugs of abuse and alcohol consumption among different groups of population on the Greek Island of Lesvos through sewage-based epidemiology by Gatidou, Georgia, Kinyua, Juliet, van Nuijs, Alexander L.N., Gracia-Lor, Emma, Castiglioni, Sara, Covaci, Adrian, Stasinakis, Athanasios S.

“…The occurrence of 22 drugs of abuse, their metabolites, and the alcohol metabolite ethyl sulphate was investigated in raw sewage samples collected during the…”
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Application of a sewage-based approach to assess the use of ten illicit drugs in four Chinese megacities by Khan, Usman, van Nuijs, Alexander L.N., Li, Jing, Maho, Walid, Du, Peng, Li, Kaiyang, Hou, Linlin, Zhang, Jiying, Meng, Xiangzhou, Li, Xiqing, Covaci, Adrian

“…Sewage-based epidemiology was applied for the first time to a number of mainland Chinese megacities. The application monitored influents to 9 sewage treatment…”
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In vitro Phase I and Phase II metabolism of α-pyrrolidinovalerophenone (α-PVP), methylenedioxypyrovalerone (MDPV) and methedrone by human liver microsomes and human liver cytosol by Negreira, Noelia, Erratico, Claudio, Kosjek, Tina, van Nuijs, Alexander L. N, Heath, Ester, Neels, Hugo, Covaci, Adrian

“…The aim of the present study was to identify the in vitro Phase I and Phase II metabolites of three new psychoactive substances: α-pyrrolidinovalerophenone…”
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Local conversion of redox inactive molecules into redox active ones: A formaldehyde based strategy for the electrochemical detection of illicit drugs containing primary and secondary amines by Schram, Jonas, Shanmugam, Saranya Thiruvottriyur, Sleegers, Nick, Florea, Anca, Samyn, Nele, van Nuijs, Alexander L.N., De Wael, Karolien

“…•Formaldehyde to allow the electrochemical detection of illicit drugs containing primary and secondary amines.•LC-MS/MS confirmation of derivatization…”
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A prospective trial of thalidomide for the treatment of HIV-associated idiopathic esophageal ulcers by Alexander, L N, Wilcox, C M

“…Thalidomide appears to be highly effective for oropharyngeal apthous ulcers in HIV-infected patients. However, there are limited data regarding the use of this…”
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Qualitative screening of new psychoactive substances in pooled urine samples from Belgium and United Kingdom by Kinyua, Juliet, Negreira, Noelia, Miserez, Bram, Causanilles, Ana, Emke, Erik, Gremeaux, Lies, de Voogt, Pim, Ramsey, John, Covaci, Adrian, van Nuijs, Alexander L.N.

“…Concerns about new psychoactive substances (NPS) are increasing due to the rising frequency of serious intoxications. Analysis of biological fluids (urine) is…”
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Sewage epidemiology — A real-time approach to estimate the consumption of illicit drugs in Brussels, Belgium by van Nuijs, Alexander L.N., Mougel, Jean-François, Tarcomnicu, Isabela, Bervoets, Lieven, Blust, Ronny, Jorens, Philippe G., Neels, Hugo, Covaci, Adrian

“…The sewage epidemiology approach was applied to a one-year sampling campaign in the largest wastewater treatment plant (WWTP) in Belgium. The consumption of…”
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Improving wastewater-based epidemiology to estimate cannabis use: focus on the initial aspects of the analytical procedure by Causanilles, Ana, Baz-Lomba, Jose Antonio, Burgard, Daniel A., Emke, Erik, González-Mariño, Iria, Krizman-Matasic, Ivona, Li, Angela, Löve, Arndís S.C., McCall, Ann Kathrin, Montes, Rosa, van Nuijs, Alexander L.N., Ort, Christoph, Quintana, José B., Senta, Ivan, Terzic, Senka, Hernandez, Félix, de Voogt, Pim, Bijlsma, Lubertus

“…Wastewater-based epidemiology is a promising and complementary tool for estimating drug use by the general population, based on the quantitative analysis of…”
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Ethyl glucuronide and alcohol abstinence: A correlation study in hair and fingernails to establish a cut-off value in fingernails for teetotalers by Vermeulen, Louise, van Nuijs, Alexander L.N., Crunelle, Cleo L., Jacobs, Werner, Neels, Hugo

“…Excessive use of alcohol increases the risk to be involved in a road traffic accident. According to many legislations, certain maximal…”
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Application of hydrophilic interaction chromatography for the analysis of polar contaminants in food and environmental samples by van Nuijs, Alexander L.N., Tarcomnicu, Isabela, Covaci, Adrian

“…For the analysis of highly hydrophilic and polar compounds, Hydrophilic Interaction Chromatography (HILIC) has been established as a valuable complementary…”
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Cephalosporin Antibiotics: Electrochemical Fingerprints and Core Structure Reactions Investigated by LC–MS/MS by Sleegers, Nick, van Nuijs, Alexander L.N, van den Berg, Marco, De Wael, Karolien

“…Electrochemistry and exploiting electrochemical fingerprints is a potent approach to address newly emerging surveillance needs, for instance, for antibiotics…”
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data-independent acquisition workflow for qualitative screening of new psychoactive substances in biological samples by Kinyua, Juliet, Negreira, Noelia, Ibáñez, María, Bijlsma, Lubertus, Hernández, Félix, Covaci, Adrian, van Nuijs, Alexander L. N

“…Identification of new psychoactive substances (NPS) is challenging. Developing targeted methods for their analysis can be difficult and costly due to their…”
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Temporal monitoring of stimulants during the COVID-19 pandemic in Belgium through the analysis of influent wastewater by Boogaerts, Tim, Quireyns, Maarten, De prins, Maarten, Pussig, Bram, De Loof, Hans, Matheï, Catharina, Aertgeerts, Bert, Van Coppenolle, Virginie, Fransen, Erik, Covaci, Adrian, van Nuijs, Alexander L.N.

“…•Stimulant use in Belgium remained stable during the first wave of COVID-19 crisis.•Employed COVID-19 countermeasures had a limited effect on the overall…”
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Profiles and changes in stimulant use in Belgium in the period of 2011–2015 by Been, Frederic, Lai, Foon Yin, Kinyua, Juliet, Covaci, Adrian, van Nuijs, Alexander L.N.

“…Adapting illicit drug policy strategies requires detailed knowledge on types and amounts of substances consumed by the target population. In this study, we…”
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Ethyl glucuronide in keratinous matrices as biomarker of alcohol use: A correlation study between hair and nails by Cappelle, Delphine, Neels, Hugo, De Keukeleire, Steven, Fransen, Erik, Dom, Geert, Vermassen, Annemie, Covaci, Adrian, Crunelle, Cleo L., van Nuijs, Alexander L.N.

“…•Evaluation of EtG concentrations in hair, finger- and toenails.•EtG levels in hair and nails significantly and positively correlated.•Higher concentrations…”
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Out of pocket expenses: effect of fee-waivers on opioid prescribing and dispensing by Boogaerts, Tim, De Swert, Chanel, Covaci, Adrian, van Nuijs, Alexander L.N., Hamelinck, Wouter, Saevels, Jan, De Loof, Hans

“…Pharmaceutical reimbursement policies should aim for satisfactory health care at reasonable prices and assure treatment adherence while avoiding wasteful…”
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