Search Results - "Alexander, H. Richard"

Jeffrey Norton and the Legacy of the Surgical Metabolism Section of the Surgery Branch of the NCI by Richard Alexander, H.

Get full text

Mesothelioma: Scientific clues for prevention, diagnosis, and therapy by Carbone, Michele, Adusumilli, Prasad S., Alexander, H. Richard, Baas, Paul, Bardelli, Fabrizio, Bononi, Angela, Bueno, Raphael, Felley‐Bosco, Emanuela, Galateau‐Salle, Francoise, Jablons, David, Mansfield, Aaron S., Minaai, Michael, Perrot, Marc, Pesavento, Patricia, Rusch, Valerie, Severson, David T., Taioli, Emanuela, Tsao, Anne, Woodard, Gavitt, Yang, Haining, Zauderer, Marjorie G., Pass, Harvey I.

“…Mesothelioma affects mostly older individuals who have been occupationally exposed to asbestos. The global mesothelioma incidence and mortality rates are…”
Get full text

Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer by GENG ZHANG, PEIJUN HE, HANNA, Nader, RICHARD ALEXANDER, H, PERWEZ HUSSAIN, S, HANSON TAN, BUDHU, Anuradha, GAEDCKE, Jochen, MICHAEL GHADIMI, B, RIED, Thomas, YFANTIS, Harris G, LEE, Dong H, MAITRA, Anirban

“…To identify metabolic pathways that are perturbed in pancreatic ductal adenocarcinoma (PDAC), we investigated gene-metabolite networks with integration of…”
Get full text

Bias and Pancreatic Cancer Reporting by Hochster, Howard S, Alexander, H Richard

Get full text

The contemporary management of peritoneal metastasis: A journey from the cold past of treatment futility to a warm present and a bright future by Foster, Jason M., Zhang, Chunmeng, Rehman, Shahyan, Sharma, Prateek, Alexander, H. Richard

“…Peritoneal metastasis (PM) is often regarded as a less frequent pattern of spread; however, collectively across all spectra of primary tumors, the consequences…”
Get full text

Phase I and Pharmacokinetic Studies of CYT-6091, a Novel PEGylated Colloidal Gold-rhTNF Nanomedicine by LIBUTTI, Steven K, PACIOTTI, Giulio F, BYRNES, Adriana A, ALEXANDER, H. Richard, GANNON, William E, WALKER, Melissa, SEIDEL, Geoffrey D, YULDASHEVA, Nargiza, TAMARKIN, Lawrence

“…A novel nanomedicine, CYT-6091, constructed by simultaneously binding recombinant human tumor necrosis factor alpha (rhTNF) and thiolyated polyethylene glycol…”
Get full text

A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2 by Yang, Shouhui, He, Peijun, Wang, Jian, Schetter, Aaron, Tang, Wei, Funamizu, Naotake, Yanaga, Katsuhiko, Uwagawa, Tadashi, Satoskar, Abhay R, Gaedcke, Jochen, Bernhardt, Markus, Ghadimi, B Michael, Gaida, Matthias M, Bergmann, Frank, Werner, Jens, Ried, Thomas, Hanna, Nader, Alexander, H Richard, Hussain, S Perwez

“…Pancreatic cancers with aberrant expression of macrophage migration inhibitory factor (MIF) are particularly aggressive. To identify key signaling pathways…”
Get full text

Results of a Randomized Controlled Multicenter Phase III Trial of Percutaneous Hepatic Perfusion Compared with Best Available Care for Patients with Melanoma Liver Metastases by Hughes, Marybeth S., Zager, Jonathan, Faries, Mark, Alexander, H. Richard, Royal, Richard E., Wood, Bradford, Choi, Junsung, McCluskey, Kevin, Whitman, Eric, Agarwala, Sanjiv, Siskin, Gary, Nutting, Charles, Toomey, Mary Ann, Webb, Carole, Beresnev, Tatiana, Pingpank, James F.

“…Purpose There is no consensus for the treatment of melanoma metastatic to the liver. Percutaneous hepatic perfusion with melphalan (PHP-Mel) is a method of…”
Get full text

The YAP1 Signaling Inhibitors, Verteporfin and CA3, Suppress the Mesothelioma Cancer Stem Cell Phenotype by Kandasamy, Sivaveera, Adhikary, Gautam, Rorke, Ellen A, Friedberg, Joseph S, Mickle, McKayla B, Alexander, H Richard, Eckert, Richard L

“…Mesothelioma is an aggressive cancer that has a poor prognosis. Tumors develop in the mesothelial lining of the pleural and peritoneal cavities in response to…”
Get full text

Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment by Lewis, Anne M, Varghese, Sheelu, Xu, Hui, Alexander, H Richard

“…The tumor microenvironment consists of tumor, immune, stromal, and inflammatory cells which produce cytokines, growth factors, and adhesion molecules that…”
Get full text

Treatment factors associated with long-term survival after cytoreductive surgery and regional chemotherapy for patients with malignant peritoneal mesothelioma by Alexander, H. Richard, MD, Bartlett, David L., MD, Pingpank, James F., MD, Libutti, Steven K., MD, Royal, Richard, MD, Hughes, Marybeth S., MD, Holtzman, Matthew, MD, Hanna, Nader, MD, Turner, Keli, MD, Beresneva, Tatiana, MD, Zhu, Yue, MD, MS

“…Objectives Malignant peritoneal mesothelioma (MPM) is a primary cancer that arises diffusely from the mesothelial cells lining the peritoneum. Morbidity and…”
Get full text

Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma by Funamizu, Naotake, Hu, Chaoxin, Lacy, Curtis, Schetter, Aaron, Zhang, Geng, He, Peijun, Gaedcke, Jochen, Ghadimi, Michael B., Ried, Thomas, Yfantis, Harris G., Lee, Dong H., Subleski, Jeffrey, Chan, Tim, Weiss, Jonathan M., Back, Timothy C., Yanaga, Katsuhiko, Hanna, Nader, Alexander, H. Richard, Maitra, Anirban, Hussain, S. Perwez

“…MIF is a proinflammatory cytokine and is implicated in cancer. A higher MIF level is found in many human cancer and cancer‐prone inflammatory diseases,…”
Get full text

Preoperative Thrombocytosis Predicts Shortened Survival in Patients with Malignant Peritoneal Mesothelioma Undergoing Operative Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy by Li, Yue C., Khashab, Tamara, Terhune, Julia, Eckert, Richard L., Hanna, Nader, Burke, Allen, Richard Alexander, H.

“…Background This study was designed to determine the clinical significance of preoperative thrombocytosis in patients with malignant peritoneal mesothelioma…”
Get full text

Current Management and Future Opportunities for Peritoneal Metastases: Peritoneal Mesothelioma by Alexander, H. Richard, Li, Claire Yue, Kennedy, Timothy J.

“…Purpose Diffuse malignant peritoneal mesothelioma (MPM) is a rare and ultimately fatal cancer that was first described just over a century ago. It is a diffuse…”
Get full text

Together We Make a Difference by Turaga, Kiran K., Clark Gamblin, T., Richard Alexander, H., Edwards, Robert, Bartlett, David L.

Get full text

Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 Mutations by Carbone, Michele, Pass, Harvey I, Ak, Guntulu, Alexander, Jr, H Richard, Baas, Paul, Baumann, Francine, Blakely, Andrew M, Bueno, Raphael, Bzura, Aleksandra, Cardillo, Giuseppe, Churpek, Jane E, Dianzani, Irma, De Rienzo, Assunta, Emi, Mitsuru, Emri, Salih, Felley-Bosco, Emanuela, Fennell, Dean A, Flores, Raja M, Grosso, Federica, Hayward, Nicholas K, Hesdorffer, Mary, Hoang, Chuong D, Johansson, Peter A, Kindler, Hedy L, Kittaneh, Muaiad, Krausz, Thomas, Mansfield, Aaron, Metintas, Muzaffer, Minaai, Michael, Mutti, Luciano, Nielsen, Maartje, O'Byrne, Kenneth, Opitz, Isabelle, Pastorino, Sandra, Pentimalli, Francesca, de Perrot, Marc, Pritchard, Antonia, Ripley, Robert Taylor, Robinson, Bruce, Rusch, Valerie, Taioli, Emanuela, Takinishi, Yasutaka, Tanji, Mika, Tsao, Anne S, Tuncer, A Murat, Walpole, Sebastian, Wolf, Andrea, Yang, Haining, Yoshikawa, Yoshie, Zolondick, Alicia, Schrump, David S, Hassan, Raffit

“…The most common malignancies that develop in carriers of BAP1 germline mutations include diffuse malignant mesothelioma, uveal and cutaneous melanoma, renal…”
Get more information

Localization of Insulinomas to Regions of the Pancreas by Intraarterial Calcium Stimulation: The NIH Experience by Guettier, Jean-Marc, Kam, Anthony, Chang, Richard, Skarulis, Monica C., Cochran, Craig, Alexander, H. Richard, Libutti, Steven K., Pingpank, James F., Gorden, Phillip

“…Context: Selective intraarterial calcium injection of the major pancreatic arteries with hepatic venous sampling [calcium arterial stimulation (CaStim)] has…”
Get full text

Desmoid-type fibromatosis in the setting of malignant peritoneal mesothelioma: a case report of two rare diseases by Gregory, Stephanie N, Satterwhite, Audra A, Alexander, H. Richard, Blakely, Andrew M

“…Abstract Background Desmoid-type fibromatosis (DTF) is a rare benign lesion that usually arises from the abdominal wall or extremities and rarely from the…”
Get full text

Multipotent cancer stem cells derived from human malignant peritoneal mesothelioma promote tumorigenesis by Varghese, Sheelu, Whipple, Rebecca, Martin, Stuart S, Alexander, H Richard

“…During the progression of malignant peritoneal mesothelioma (MPeM), tumor nodules propagate diffusely within the abdomen and tumors are characterized by…”
Get full text

Endothelial Nitric Oxide Synthase Traffic Inducer (NOSTRIN) is a Negative Regulator of Disease Aggressiveness in Pancreatic Cancer by Wang, Jian, Yang, Shouhui, He, Peijun, Schetter, Aaron J, Gaedcke, Jochen, Ghadimi, B Michael, Ried, Thomas, Yfantis, Harris G, Lee, Dong H, Gaida, Matthias M, Hanna, Nader, Alexander, H Richard, Hussain, S Perwez

“…Pancreatic ductal adenocarcinoma (PDAC) is refractory to available treatments. Delineating critical pathways, responsible for disease aggressiveness and…”
Get full text