Search Results - "Alexander, Ella"
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Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival
Published in Molecular immunology (01-11-2017)“…•The transcriptional elongation factor ELL3 is up-regulated in activated B cells.•Two ELL family members are non-concurrently expressed at specific B cell…”
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Data supporting the functional role of Eleven-nineteen Lysine-rich Leukemia 3 (ELL3) in B cell lymphoma cell line cells
Published in Data in brief (01-12-2017)“…The data presented here are related to the research article entitled “Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2…”
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Mapping of citrullinated fibrinogen B-cell epitopes in rheumatoid arthritis by imaging surface plasmon resonance
Published in Arthritis research & therapy (01-01-2010)“…Rheumatoid arthritis (RA) frequently involves the loss of tolerance to citrullinated antigens, which may play a role in pathogenicity. Citrullinated fibrinogen…”
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In Vitro Optimization of Non-Small Cell Lung Cancer Activity with Troxacitabine, l-1,3-Dioxolane-cytidine, Prodrugs
Published in Journal of medicinal chemistry (03-05-2007)“…l-1,3-Dioxolane-cytidine, a potent anticancer agent against leukemia, has limited efficacy against solid tumors, perhaps due to its hydrophilicity. Herein, a…”
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H3K27me3 Demethylase UTX Restrains Plasma Cell Formation
Published in The Journal of immunology (1950) (15-04-2022)“…B cell differentiation is associated with substantial transcriptional, metabolic, and epigenetic remodeling, including redistribution of histone 3 lysine 27…”
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Epigenomic Profiling of B Cell Subsets by CUT&Tag
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Epigenetic programs play a key role in regulating the development and function of immune cells. However, conventional methods for profiling epigenetic…”
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Comment on: Pinhole pupilloplasty after previous radial keratotomy
Published in Journal of cataract and refractive surgery (01-10-2021)Get full text
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Surgical peripheral iridotomy creation during intraocular surgery by intraocular diathermy probe—a novel technique
Published in European journal of ophthalmology (01-05-2022)“…A novel technique for the creation of surgical iridotomies using a bipolar diathermic probe is described. In a cohort comprising 19 eyes of 18 patients, a 100%…”
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IL-6/STAT3 Signaling Axis Enhances and Prolongs Pdcd1 Expression in Murine CD8 T Cells
Published in ImmunoHorizons (01-12-2022)“…CD8 cytotoxic T cells are a potent line of defense against invading pathogens. To aid in curtailing aberrant immune responses, the activation status of CD8 T…”
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H3K9 dimethyltransferase G9a is an important epigenetic modulator of B cell differentiation
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract Plasma cell differentiation is a tightly regulated process coordinated by the timed expression of several transcription factors as well as histone…”
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H3K9 dimethyltransferase G9a deficiency modulates B-cell response to LPS
Published in The Journal of immunology (1950) (01-05-2021)“…Abstract B cell differentiation is a tightly regulated process coordinated by the timed expression of various transcription factors and chromatin accessibility…”
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H3K9 dimethyltransferase G9a is an important epigenetic modulator of B cell differentiation
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract B cell differentiation is a tightly regulated process coordinated by the timed expression of various transcription factors and chromatin accessibility…”
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Abstract 2331: Transcriptional repressor PRDM1/Blimp-1 directly regulates transcriptional elongation factor ELL3 during terminal B-cell differentiation
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Abstract As the master regulator of B-cell differentiation, PRDM1 is well known for its ability to extinguish a network of transcription factors essential in…”
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Characterization of the Transcriptional Elongation Factor ELL3 in B cells and Its Role in B-cell Lymphoma Proliferation and Survival
Published 01-01-2018“…The studies presented in this dissertation establish the dynamics of Eleven nineteen Lysine-rich leukemia (ELL) family of elongation factors during B cell…”
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Dissertation -
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H3K27me3-specific demethylases modulate B cell development and differentiation
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract B cell terminal differentiation into antibody secreting plasma cells (ASC) must be properly regulated to ensure robust humoral immune responses…”
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Marian Keyes novelist
Published in Sunday telegraph (London, England) (21-06-2009)Get full text
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