Search Results - "Alex McMahan, C."
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Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Risk Score in Young Adults Predicts Coronary Artery and Abdominal Aorta Calcium in Middle Age: The CARDIA Study
Published in Circulation (New York, N.Y.) (12-01-2016)“…BACKGROUND—We explored whether, the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) coronary and abdominal risk scores measured at 18 to 30…”
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High fat diet induced insulin resistance and glucose intolerance are gender-specific in IGF-1R heterozygous mice
Published in Biochemical and biophysical research communications (30-09-2011)“…► Interaction between genes and environment is critical in pathogenesis of diabetes. ► Reduced IGF-1 action is associated with low birth weight and post-natal…”
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Conventional SLA and chemically modified SLA implants in patients with poorly controlled type 2 Diabetes mellitus - a randomized controlled trial
Published in Clinical oral implants research (01-01-2013)“…Objective The objective of this study was to evaluate the potential for a chemically modified Sand blasted, Large grit, Acid etched (SLA) surface, compared…”
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Enhanced Genetic Integrity in Mouse Germ Cells
Published in Biology of reproduction (2013)“…Genetically based diseases constitute a major human health burden, and de novo germline mutations represent a source of heritable genetic alterations that can…”
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Early-life exposure to benzo[a]pyrene increases mutant frequency in spermatogenic cells in adulthood
Published in PloS one (29-01-2014)“…Children are vulnerable to environmental mutagens, and the developing germline could also be affected. However, little is known about whether exposure to…”
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Obesity accelerates the progression of coronary atherosclerosis in young men
Published in Circulation (New York, N.Y.) (11-06-2002)“…Obesity is a risk factor for adult coronary heart disease and is increasing in prevalence among youths as well as adults. Results regarding the association of…”
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Number of basis images effect on detection of root fractures in endodontically treated teeth using a cone beam computed tomography machine: an in vitro study
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-05-2013)“…Objectives The objective of this study was to compare the accuracy of root fracture detection in endodontically treated teeth using scans acquired with a 180°…”
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Contrast-to-noise ratio with different large volumes in a cone-beam computerized tomography machine: An in vitro study
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-11-2012)“…Objectives The objectives were to determine whether the images obtained from different cone-beam computerized tomography (CBCT) field of view (FOV) sizes with…”
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Origin of atherosclerosis in childhood and adolescence
Published in The American journal of clinical nutrition (01-11-2000)“…Atherosclerosis begins in childhood as deposits of cholesterol and its esters, referred to as fatty streaks, in the intima of large muscular arteries. In some…”
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Association of Pathobiologic Determinants of Atherosclerosis in Youth Risk Score and 15-Year Change in Risk Score With Carotid Artery Intima–Media Thickness in Young Adults (from the Cardiovascular Risk in Young Finns Study)
Published in The American journal of cardiology (01-10-2007)“…The Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study of autopsy findings in subjects 15 to 34 years of age developed a risk score using…”
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Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissues
Published in Mechanisms of ageing and development (01-09-2008)“…Genetic instability has been implicated as a causal factor in cancer and aging. Caloric restriction (CR) and suppression of the somatotroph axis significantly…”
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Effects of Coronary Heart Disease Risk Factors on Atherosclerosis of Selected Regions of the Aorta and Right Coronary Artery
Published in Arteriosclerosis, thrombosis, and vascular biology (01-03-2000)“…ABSTRACTWe examined topographic distributions of atherosclerosis and their relation to risk factors for adult coronary heart disease in right coronary arteries…”
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Effects of Serum Lipoproteins and Smoking on Atherosclerosis in Young Men and Women
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-1997)“…Atherosclerosis begins in childhood and progresses from fatty streaks to raised lesions in adolescence and young adulthood. A cooperative multicenter study…”
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Epigenetic regulation of genetic integrity is reprogrammed during cloning
Published in Proceedings of the National Academy of Sciences - PNAS (24-03-2009)“…Cloning by somatic cell nuclear transfer (SCNT) circumvents processes that normally function during gametogenesis to prepare the gamete genomes to support…”
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Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice
Published in Molecular reproduction and development (01-12-2011)“…The prevalence of spontaneous mutations increases with age in the male germline; consequently, older men have an increased risk of siring children with genetic…”
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Recovery of a low mutant frequency after ionizing radiation-induced mutagenesis during spermatogenesis
Published in Mutation research (31-07-2008)“…Humans are exposed to ionizing radiation (IR) under various circumstances, e.g. cosmic radiation, diagnostic X-rays and radiotherapy for cancer. It has been…”
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Assisted reproductive technologies do not alter mutation frequency or spectrum
Published in Proceedings of the National Academy of Sciences - PNAS (20-03-2007)“…Assisted reproductive technologies (ARTs) have now contributed to the birth of >3 million babies worldwide, but concerns remain regarding the safety of these…”
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Rapid Gastric emptying in spontaneously hypertensive rats
Published in Journal of hypertension (01-03-2024)“…To assess the rate of gastric emptying in spontaneously hypertensive rats (SHR) and to evaluate rapid gastric emptying as a possible predisposing factor for…”
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Elevated Serum C-Reactive Protein Levels and Advanced Atherosclerosis in Youth
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2005)“…OBJECTIVE—To determine the associations among serum C-reactive protein (CRP) concentration, age, sex, risk factors for coronary heart disease (CHD), and…”
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