Search Results - "Alex Durand Nka"
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Detection of Gag C-terminal mutations among HIV-1 non-B subtypes in a subset of Cameroonian patients
Published in Scientific reports (26-01-2022)“…Response to ritonavir-boosted-protease inhibitors (PI/r)-based regimen is associated with some Gag mutations among HIV-1 B-clade. There is limited data on Gag…”
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The 2nd International Conference on Public Health in Africa 12-15 December 2022, Kigali, Rwanda
Published in Journal of public health in Africa (28-02-2023)Get full text
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HIV-1 residual risk and pre-treatment drug resistance among blood donors: A sentinel surveillance from Gabon
Published in PloS one (03-09-2024)“…Surveillance of HIV-1 pre-treatment drug resistance (PDR) is essential for ensuring the success of first-line antiretroviral therapy (ART). Beside…”
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Global burden of SARS-CoV-2 infection, hospitalization and case fatality rate among COVID-19 vaccinated individuals and its associated factors: A systematic review and meta-analysis protocol
Published in PloS one (09-08-2022)“…Background COVID-19 has been the most important public health concern worldwide since 2020. Several vaccines are now available to help in controlling COVID-19…”
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Correlation between the immuno-virological response and the nutritional profile of treatment-experienced HIV-infected patients in the East region of Cameroon
Published in PloS one (13-05-2021)“…HIV management remains concerning and even more challenging in the frame of comorbidities like malnutrition that favors disease progression and mortality in…”
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HIV-1 subtype diversity and immuno-virological outcomes among adolescents failing antiretroviral therapy in Cameroon: A cohort study
Published in PloS one (25-10-2023)“…OBJECTIVEWe sought to evaluate the variability of HIV-1 and its effect on immuno-virological response among adolescents living with perinatally acquired HIV…”
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The mother-to-child transmission of HIV-1 and profile of viral reservoirs in pediatric population: A systematic review with meta-analysis of the Cameroonian studies
Published in PloS one (17-01-2023)“…The mother-to-child transmission of HIV-1 (MTCT) remains on the major route of HIV-transmission among pediatric populations in Africa. Though a prevention of…”
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HIV-1 Gag gene mutations, treatment response and drug resistance to protease inhibitors: A systematic review and meta-analysis protocol
Published in PloS one (01-07-2021)“…Some mutations in the HIV-1 Gag gene are known to confer resistance to ritonavir-boosted protease inhibitors (PI/r), but their clinical implications remain…”
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Global prevalence and case fatality rate of Enterovirus D68 infections, a systematic review and meta-analysis
Published in PLoS neglected tropical diseases (01-02-2022)“…A substantial amount of epidemiological data has been reported on Enterovirus D68 (EV-D68) infections after the 2014 outbreak. Our goal was to map the case…”
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Characterisation of HIV-1 reservoirs in paediatric populations: protocol for a systematic review and meta-analysis
Published in BMJ open (10-10-2023)“…IntroductionThe success of antiretroviral therapy (ART) has changed HIV from a deadly to a chronic infection, thus increasing the transitioning from infancy…”
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Pre-existing immunity to SARS-CoV-2 before the COVID-19 pandemic era in Cameroon: A comparative analysis according to HIV-status
Published in Frontiers in immunology (08-03-2023)“…The lower burden of COVID-19 in tropical settings may be due to preexisting cross-immunity, which might vary according to geographical locations and potential…”
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Evaluation of archived drug resistance mutations in HIV‐1 DNA among vertically infected adolescents under antiretroviral treatment in Cameroon: Findings during the COVID‐19 pandemic
Published in HIV medicine (01-06-2023)“…Background With the success of antiretroviral therapy (ART), children born with HIV are more likely to reach adolescence. However, frequent non‐adherence to…”
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Inflammatory profile of vertically HIV-1 infected adolescents receiving ART in Cameroon: a contribution toward optimal pediatric HIV control strategies
Published in Frontiers in immunology (14-08-2023)“…Antiretroviral therapy (ART) has improved the lifespan of people living with HIV. However, their immune system remains in a state of sustained…”
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Dolutegravir-Based Regimen Ensures High Virological Success despite Prior Exposure to Efavirenz-Based First-LINE ART in Cameroon: An Evidence of a Successful Transition Model
Published in Viruses (21-12-2022)“…To ensure optimal prescribing practices in the dolutegravir-era in Cameroon, we compared first-line virological response (VR) under tenofovir + lamivudine +…”
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Viral suppression in adults, adolescents and children receiving antiretroviral therapy in Cameroon: adolescents at high risk of virological failure in the era of "test and treat"
Published in AIDS research and therapy (19-11-2019)“…After the launching of the « Test & Treat » strategy and the wider accessibility to viral load (VL), evaluating virological success (VS) would help in meeting…”
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Human immunodeficiency virus is a driven factor of human papilloma virus among women: evidence from a cross-sectional analysis in Yaoundé, Cameroon
Published in Virology journal (19-05-2020)“…Human papillomavirus (HPV) is the leading cause of cervical cancers, causing 270.000 deaths annually worldwide of which 85% occur in developing countries with…”
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Thrombocytopenia according to antiretroviral drug combinations, viremia and CD4 lymphocytes among HIV-infected patients in Cameroon: a snapshot from the City of Yaoundé
Published in BMC research notes (26-09-2019)“…Thrombocytopenia is an abnormal decrease in blood platelets, which can affect the prognosis of people living with HIV (PLHIV). In order to assess the burden of…”
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Determinants of periodontitis according to the immunological and virological profiles of HIV-infected patients in Yaoundé, Cameroon
Published in BMC oral health (11-12-2020)“…HIV infection is associated to different oral manifestations (including periodontal diseases), which have decreased with the advent of antiretroviral therapy…”
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Empowering adolescents living with perinatally-acquired HIV: tailored CD4+ count assessment for optimized care, the EDCTP READY-study
Published in Frontiers in medicine (20-09-2024)“…The elevated rate of AIDS-related mortality in Sub-Saharan Africa among adolescents living with HIV (ALHIV) is influenced by various factors, notably…”
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Evaluation of Viral Suppression in Paediatric Populations: Implications for the Transition to Dolutegravir-Based Regimens in Cameroon: The CIPHER-ADOLA Study
Published in Biomedicines (12-09-2024)“…Mortality in children accounts for 15% of all AIDS-related deaths globally, with a higher burden among Cameroonian children (25%), likely driven by poor…”
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