Search Results - "Alewel, Devin I"

Serum metabolome and liver transcriptome reveal acrolein inhalation-induced sex-specific homeostatic dysfunction by Alewel, Devin I., Rentschler, Katherine M., Jackson, Thomas W., Schladweiler, Mette C., Astriab-Fisher, Anna, Evansky, Paul A., Kodavanti, Urmila P.

“…Acrolein, a respiratory irritant, induces systemic neuroendocrine stress. However, peripheral metabolic effects have not been examined. Male and female WKY…”
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Differential transcriptomic alterations in nasal versus lung tissue of acrolein-exposed rats by Alewel, Devin I, Jackson, Thomas W, Rentschler, Katherine M, Schladweiler, Mette C, Astriab-Fisher, Anna, Gavett, Stephen H, Evansky, Paul A, Kodavanti, Urmila P

“…Acrolein is a significant component of anthropogenic and wildfire emissions, as well as cigarette smoke. Although acrolein primarily deposits in the upper…”
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Neuroendocrine contribution to sex-related variations in adverse air pollution health effects by Alewel, Devin I., Kodavanti, Urmila P.

“…Air pollution exposure is ranked as a leading environmental risk factor for not only cardiopulmonary diseases but also for systemic health ailments including…”
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Air Pollutant impacts on the brain and neuroendocrine system with implications for peripheral organs: a perspective by Kodavanti, Urmila P., Jackson, Thomas W., Henriquez, Andres R., Snow, Samantha J., Alewel, Devin I., Costa, Daniel L.

“…Air pollutants are being increasingly linked to extrapulmonary multi-organ effects. Specifically, recent studies associate air pollutants with brain disorders…”
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The contribution of the neuroendocrine system to adaption after repeated daily ozone exposure in rats by Henriquez, Andres R., Snow, Samantha J., Dye, Janice A., Schladweiler, Mette C., Alewel, Devin I., Miller, Colette N., Kodavanti, Urmila P.

“…Ozone-induced lung injury/inflammation dissipates despite continued exposure for 3 or more days; however, the mechanisms of adaptation/habituation remain…”
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Sex-specific respiratory and systemic endocrine effects of acute acrolein and trichloroethylene inhalation by Alewel, Devin I., Jackson, Thomas W., Vance, Samuel A., Schladweiler, Mette C., Evansky, Paul A., Henriquez, Andres R., Grindstaff, Rachel, Gavett, Stephen H., Kodavanti, Urmila P.

“…Acrolein and trichloroethylene (TCE) are priority hazardous air pollutants due to environmental prevalence and adverse health effects; however, neuroendocrine…”
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Adrenal Stress Hormone Regulation of Hepatic Homeostatic Function After an Acute Ozone Exposure in Wistar-Kyoto Male Rats by Jackson, Thomas W, Henriquez, Andres R, Snow, Samantha J, Schladweiler, Mette C, Fisher, Anna A, Alewel, Devin I, House, John S, Kodavanti, Urmila P

“…Abstract Ozone-induced lung injury, inflammation, and pulmonary/hypothalamus gene expression changes are diminished in adrenalectomized (AD) rats. Acute ozone…”
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Stress Drivers of Glucose Dynamics during Ozone Exposure Measured Using Radiotelemetry in Rats by Henriquez, Andres R, Snow, Samantha J, Jackson, Thomas W, House, John S, Motsinger-Reif, Alison A, Ward-Caviness, Cavin K, Schladweiler, Mette C, Alewel, Devin I, Miller, Colette N, Farraj, Aimen K, Hazari, Mehdi S, Grindstaff, Rachel, Diaz-Sanchez, David, Ghio, Andrew J, Kodavanti, Urmila P

“…Inhaled irritant air pollutants may trigger stress-related metabolic dysfunction associated with altered circulating adrenal-derived hormones. We used…”
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Social isolation exacerbates acute ozone inhalation induced pulmonary and systemic health outcomes by Henriquez, Andres R., Snow, Samantha J., Jackson, Thomas W., House, John S., Alewel, Devin I., Schladweiler, Mette C., Valdez, Matthew C., Freeborn, Danielle L., Miller, Colette N., Grindstaff, Rachel, Kodavanti, Prasada Rao S., Kodavanti, Urmila P.

“…Psychosocially-stressed individuals might have exacerbated responses to air pollution exposure. Acute ozone exposure activates the neuroendocrine stress…”
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Intratracheal instillation of respirable particulate matter elicits neuroendocrine activation by Alewel, Devin I., Henriquez, Andres R., Schladweiler, Mette C., Grindstaff, Rachel, Fisher, Anna A., Snow, Samantha J., Jackson, Thomas W., Kodavanti, Urmila P.

“…Inhalation of ozone activates central sympathetic-adrenal-medullary and hypothalamic-pituitary-adrenal stress axes. While airway neural networks are known to…”
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Multi-tissue transcriptomic and serum metabolomic assessment reveals systemic implications of acute ozone-induced stress response in male Wistar Kyoto rats by Jackson, Thomas W., House, John S., Henriquez, Andres R., Schladweiler, Mette C., Jackson, Kimberly MP, Fisher, Anna A., Snow, Sam J., Alewel, Devin I., Motsinger-Reif, Allison A., Kodavanti, Urmila P.

“…Air pollutant exposures have been linked to systemic disease; however, the underlying mechanisms between responses of the target tissue and systemic effects…”
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The Role of Hepatic Vagal Tone in Ozone-Induced Metabolic Dysfunction in the Liver by Colonna, Catherine H, Henriquez, Andres R, House, John S, Motsinger-Reif, Alison A, Alewel, Devin I, Fisher, Anna, Ren, Hongzu, Snow, Samantha J, Schladweiler, Mette C, Miller, Desinia B, Miller, Colette N, Kodavanti, Prasada Rao S, Kodavanti, Urmila P

“…Abstract Air pollution has been associated with metabolic diseases and hepatic steatosis-like changes. We have shown that ozone alters liver gene expression…”
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Ozone-induced acute phase response in lung versus liver: the role of adrenal-derived stress hormones by Alewel, Devin I., Henriquez, Andres R., Colonna, Catherine H., Snow, Samantha J., Schladweiler, Mette C., Miller, Colette N., Kodavanti, Urmila P.

“…Acute-phase response (APR) is an innate stress reaction to tissue trauma or injury, infection, and environmental insults like ozone (O 3 ). Regardless of the…”
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The contribution of the neuroendocrine system to adaption after repeated daily ozone exposure in rats by Henriquez, Andres R., Snow, Samantha J., Dye, Janice A., Schladweiler, Mette C., Alewel, Devin I., Miller, Colette N., Kodavanti, Urmila P.

“…Ozone-induced lung injury/inflammation dissipates despite continued exposure for 3 or more days; however, the mechanisms of adaptation/habituation remain…”
Get full text