Search Results - "Aletta, John M."

Proteomic Analysis Reveals Diverse Classes of Arginine Methylproteins in Mitochondria of Trypanosomes by Fisk, John C., Li, Jun, Wang, Hao, Aletta, John M., Qu, Jun, Read, Laurie K.

“…Arginine (arg) methylation is a widespread posttranslational modification of proteins that impacts numerous cellular processes such as chromatin remodeling,…”
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Methylation regulates the intracellular protein-protein and protein-RNA interactions of FMRP by Dolzhanskaya, Natalia, Merz, George, Aletta, John M, Denman, Robert B

“…FMRP, the fragile X mental retardation protein, is an RNA-binding protein that interacts with [approximately]4% of fetal brain mRNA. We have recently shown…”
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NGF-induced cell differentiation and gene activation is mediated by integrative nuclear FGFR1 signaling (INFS) by Lee, Yu-Wei, Stachowiak, Ewa K, Birkaya, Barbara, Terranova, Christopher, Capacchietti, Mariolina, Claus, Peter, Aletta, John M, Stachowiak, Michal K

“…Nerve growth factor (NGF) is the founding member of the polypeptide neurotrophin family responsible for neuronal differentiation. To determine whether the…”
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A Methyltransferase-independent Function for Rmt3 in Ribosomal Subunit Homeostasis by Perreault, Audrey, Gascon, Suzanne, D'Amours, Annie, Aletta, John M., Bachand, Francois

“…Schizosaccharomyces pombe Rmt3 is a member of the protein-arginine methyltransferase (PRMT) family and is the homolog of human PRMT3. We previously…”
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Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1 by Cimato, Thomas R., Tang, Jie, Xu, Ye, Guarnaccia, Corrado, Herschman, Harvey R., Pongor, Sandor, Aletta, John M.

“…Nerve growth factor (NGF)‐specific signal transduction leads to changes in protein methylation during neuronal differentiation of PC12 cells (Cimato et al…”
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Global proteomic analysis in trypanosomes reveals unique proteins and conserved cellular processes impacted by arginine methylation by Lott, Kaylen, Li, Jun, Fisk, John C., Wang, Hao, Aletta, John M., Qu, Jun, Read, Laurie K.

“…Arginine methylation is a common posttranslational modification with reported functions in transcription, RNA processing and translation, and DNA repair…”
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Coalition of Nuclear Receptors in the Nervous System by Förthmann, Benjamin, Aletta, John M., Lee, Yu-Wei, Terranova, Chris, Birkaya, Barbara, Stachowiak, Ewa K., Stachowiak, Michal K., Claus, Peter

“…A universal signaling module has been described which utilizes the nuclear form of Fibroblast growth Factor Receptor 1 (FGFR1) in a central role directing the…”
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A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells by Lee, Yu-Wei, Terranova, Christopher, Birkaya, Barbara, Narla, Sridhar, Kehoe, Daniel, Parikh, Abhirath, Dong, Shuo, Ratzka, Andreas, Brinkmann, Hella, Aletta, John M., Tzanakakis, Emmanuel S., Stachowiak, Ewa K., Claus, Peter, Stachowiak, Michal K.

“…FGF Receptor‐1 (FGFR1), a membrane‐targeted protein, is also involved in independent direct nuclear signaling. We show that nuclear accumulation of FGFR1 is a…”
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Nerve Growth Factor-Specific Regulation of Protein Methylation during Neuronal Differentiation of PC12 Cells by Cimato, Thomas R., Ettinger, Murray J., Zhou, Xianbo, Aletta, John M.

“…Protein methylation is a posttranslational modification that can potentially regulate signal transduction pathways in a similar manner as protein…”
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Accurate Localization and Relative Quantification of Arginine Methylation Using Nanoflow Liquid Chromatography Coupled to Electron Transfer Dissociation and Orbitrap Mass Spectrometry by Wang, Hao, Straubinger, Robert M., Aletta, John M., Cao, Jin, Duan, Xiaotao, Yu, Haoying, Qu, Jun

“…Protein arginine (Arg) methylation serves an important functional role in eucaryotic cells, and typically occurs in domains consisting of multiple Arg in close…”
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Targeting novel integrative nuclear FGFR1 signaling by nanoparticle-mediated gene transfer stimulates neurogenesis in the adult brain by Stachowiak, Ewa K, Roy, Indrajit, Lee, Yu-Wei, Capacchietti, Mariolina, Aletta, John M, Prasad, Paras N, Stachowiak, Michal K

“…Neurogenesis, the process of differentiation of neuronal stem/progenitor cells (NS/PC) into mature neurons, holds the key to the treatment of various…”
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Immunohistochemical detection of arginine methylated proteins (MeRP) in archival tissues by Vezzalini, Marzia, Aletta, John M, Beghelli, Stefania, Moratti, Elisabetta, Della Peruta, Marco, Mafficini, Andrea, Mojica, Wilfrido D, Mombello, Aldo, Scarpa, Aldo, Sorio, Claudio

“…Vezzalini M, Aletta J M, Beghelli S, Moratti E, Della Peruta M, Mafficini A, Mojica W D, Mombello A, Scarpa A & Sorio C
(2010) Histopathology57, 725–733 …”
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Protein methylation: a signal event in post-translational modification by Aletta, John M., Cimato, Thomas R., Ettinger, Murray J.

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Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and drbitrap mass spectrometry by Wang, Hao, Straubinger, Robert M., Aletta, John M., Cao, Jin, Duan, Xiaotao, Yu, Haoying, Qu, Jun

“…Protein arginine (Arg) methylation serves an important functional role in eucaryotic cells, and typically occurs in domains consisting of multiple Arg in close…”
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Generation of polyclonal antiserum for the detection of methylarginine proteins by Duan, Peng, Xu, Ye, Birkaya, Barbara, Myers, Jason, Pelletier, Michel, Read, Laurie K., Guarnaccia, Corrado, Pongor, Sandor, Denman, Robert B., Aletta, John M.

“…This report describes an approach for the study of the biology of methylarginine proteins based on the generation of immunological reagents capable of…”
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Protein arginine methylation in health and disease by Aletta, John M., Hu, John C.

“…Protein arginine methylation is a rapidly growing field of biomedical research that holds great promise for extending our understanding of developmental and…”
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Arginine methylation of a mitochondrial guide RNA binding protein from Trypanosoma brucei by Pelletier, Michel, Xu, Ye, Wang, Xu, Zahariev, Sotir, Pongor, Sandor, Aletta, John M, Read, Laurie K

“…RBP16 is a mitochondrial Y-box protein from the parasitic protozoan Trypanosoma brucei that binds guide RNAs and ribosomal RNAs. It is comprised of an…”
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Role of nerve growth factor in the regulation of parotid cell differentiation induced by rat serum by Takeuchi, Takashi, Aletta, John M, Laychock, Suzanne G, Tian, Yingrao, Rubin, Ronald P

“…The present study was undertaken to examine the factors that regulate rat serum (RS)- and nerve growth factor (NGF)-induced differentiation in a rat parotid…”
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Activation of a Calcium-Calmodulin-dependent Protein Kinase I Cascade in PC12 Cells by Aletta, John M., Selbert, Michele A., Nairn, Angus C., Edelman, Arthur M.

“…It has been observed that the activity of Ca2+-calmodulin (CaM)-dependent protein kinase I is enhanced up to 50-fold by its phosphorylation in vitro by a…”
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PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation by Greene, L A, Aletta, J M, Rukenstein, A, Green, S H

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