Search Results - "Alessandro Farias"

Deciphering targets of Th17 cells fate: From metabolism to nuclear receptors by Oliveira Boldrini, Vinícius, Santos Farias, Alessandro, Degasperi, Giovanna Rosa

“…Evidence indicates that reprogramming of metabolism is critically important for the differentiation of CD4 + T lymphocytes, and the manipulation of metabolic…”
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Defective Induction of IL-27-Mediated Immunoregulation by Myeloid DCs in Multiple Sclerosis by von Glehn, Felipe, Pochet, Nathalie, Thapa, Bibek, Raheja, Radhika, Mazzola, Maria A, Jangi, Sushrut, Beynon, Vanessa, Huang, Junning, Farias, Alessandro S, Paul, Anu, Santos, Leonilda M B, Gandhi, Roopali, Murugaiyan, Gopal, Weiner, Howard L, Baecher-Allan, Clare M

“…The purpose of this study was to examine whether myeloid dendritic cells (mDCs) from patients with multiple sclerosis (MS) and healthy controls (HCs) become…”
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Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis by Codo, Ana Campos, Davanzo, Gustavo Gastão, Monteiro, Lauar de Brito, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Virgilio-da-Silva, João Victor, Prodonoff, Juliana Silveira, Carregari, Victor Corasolla, de Biagi Junior, Carlos Alberto Oliveira, Crunfli, Fernanda, Jimenez Restrepo, Jeffersson Leandro, Vendramini, Pedro Henrique, Reis-de-Oliveira, Guilherme, Bispo dos Santos, Karina, Toledo-Teixeira, Daniel A., Parise, Pierina Lorencini, Martini, Matheus Cavalheiro, Marques, Rafael Elias, Carmo, Helison R., Borin, Alexandre, Coimbra, Laís Durço, Boldrini, Vinícius O., Brunetti, Natalia S., Vieira, Andre S., Mansour, Eli, Ulaf, Raisa G., Bernardes, Ana F., Nunes, Thyago A., Ribeiro, Luciana C., Palma, Andre C., Agrela, Marcus V., Moretti, Maria Luiza, Sposito, Andrei C., Pereira, Fabrício Bíscaro, Velloso, Licio Augusto, Vinolo, Marco Aurélio Ramirez, Damasio, André, Proença-Módena, José Luiz, Carvalho, Robson Francisco, Mori, Marcelo A., Martins-de-Souza, Daniel, Nakaya, Helder I., Farias, Alessandro S., Moraes-Vieira, Pedro M.

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Thymic Innervation Impairment in Experimental Autoimmune Encephalomyelitis by Francelin, Carolina, Borin, Alexandre, Funari, Jessica, Pradella, Fernando, Santos, Leonilda M.B., Savino, Wilson, Farias, Alessandro S.

“…Abstract Introduction: The thymus is the primary lymphoid organ responsible for normal T-cell development. Yet, in abnormal metabolic conditions as well as an…”
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Safety and Outcomes Associated with the Pharmacological Inhibition of the Kinin-Kallikrein System in Severe COVID-19 by Mansour, Eli, Palma, Andre C, Ulaf, Raisa G, Ribeiro, Luciana C, Bernardes, Ana Flavia, Nunes, Thyago A, Agrela, Marcus V, Bombassaro, Bruna, Monfort-Pires, Milena, Camargo, Rafael L, Araujo, Eliana P, Brunetti, Natalia S, Farias, Alessandro S, Falcão, Antônio Luís E, Santos, Thiago Martins, Trabasso, Plinio, Dertkigil, Rachel P, Dertkigil, Sergio S, Moretti, Maria Luiza, Velloso, Licio A

“…Coronavirus disease 19 (COVID-19) can develop into a severe respiratory syndrome that results in up to 40% mortality. Acute lung inflammatory edema is a major…”
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Obesity Increases Gene Expression of Markers Associated With Immunosenescence in Obese Middle-Aged Individuals by Brunelli, Diego T, Boldrini, Vinicius O, Bonfante, Ivan L P, Duft, Renata G, Mateus, Keryma, Costa, Leonardo, Chacon-Mikahil, Mara P T, Teixeira, Ana M, Farias, Alessandro S, Cavaglieri, Cláudia R

“…Recently, it has been argued that obesity leads to a chronic pro-inflammatory state that can accelerate immunosenescence, predisposing to the early acquisition…”
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Neuroprotection and immunomodulation by xenografted human mesenchymal stem cells following spinal cord ventral root avulsion by Ribeiro, Thiago B., Duarte, Adriana S. S., Longhini, Ana Leda F., Pradella, Fernando, Farias, Alessandro S., Luzo, Angela C. M., Oliveira, Alexandre L. R., Olalla Saad, Sara Teresinha

“…The present study investigates the effects of xenotransplantation of Adipose Tissue Mesenchymal Stem Cells (AT-MSCs) in animals after ventral root avulsion…”
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Therapeutic BCG vaccine protects against long COVID: The BATTLE randomized clinical trial by Jalalizadeh, Mehrsa, Buosi, Keini, Giacomelli, Cristiane F., Leme, Patricia A.F., Ferrari, Karen L., Dionato, Franciele A.V., Brito, Wandrey R.S., Brunetti, Natália S., Maia, Aline R., Morari, Joseane, Pagliarone, Ana C., Farias, Alessandro S., Velloso, Licio A., Queiroz, Maria A.F., Vallinoto, Antonio C.R., Bajgelman, Marcio C., Reis, Leonardo O.

“…Bacillus Calmette-Guérin (BCG) injected during the COVID-19 convalescence period was safe and enhanced recovery from anosmia and dysgeusia in the acute…”
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In silico analysis of mutant epitopes in new SARS-CoV-2 lineages suggest global enhanced CD8+ T cell reactivity and also signs of immune response escape by Pretti, Marco Antônio M., Galvani, Rômulo G., Scherer, Nicole M., Farias, Alessandro S., Boroni, Mariana

“…SARS-CoV-2 variants of concern have emerged since the COVID-19 outburst, notably the lineages detected in the UK, South Africa, and Brazil. Their increased…”
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Dimethyl fumarate modulates the regulatory T cell response in the mesenteric lymph nodes of mice with experimental autoimmune encephalomyelitis by Lima, Amanda D R, Ferrari, Breno B, Pradella, Fernando, Carvalho, Rodrigo M, Rivero, Sandra L S, Quintiliano, Raphael P S, Souza, Matheus A, Brunetti, Natália S, Marques, Ana M, Santos, Irene P, Farias, Alessandro S, Oliveira, Elaine C, Santos, Leonilda M B

“…Dimethyl fumarate (DMF, Tecfidera) is an oral drug utilized to treat relapsing-remitting multiple sclerosis (MS). DMF treatment reduces disease activity in MS…”
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Combined Training Improves Gene Expression Related to Immunosenescence in Obese Type 2 Diabetic Individuals by Brunelli, Diego T., Bonfante, Ivan L. P., Boldrini, Vinicius O., Scolfaro, Pedro G., Duft, Renata G., Mateus, Keryma, Fatori, Raphael F., Chacon-Mikahil, Mara P. T., Farias, Alessandro S., Teixeira, Ana M., Cavaglieri, Cláudia R.

“…Purpose: The aim of this study was to investigate the effects of moderate combined training (CT) on both the gene expression of pro- and anti-inflammatory…”
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Structural brain abnormalities are related to retinal nerve fiber layer thinning and disease duration in neuromyelitis optica spectrum disorders by von Glehn, Felipe, Jarius, Sven, Cavalcanti Lira, Rodrigo Pessoa, Alves Ferreira, Maria Carolina, von Glehn, Fadua H Ribeiro, Costa e Castro, Stella Maris, Beltramini, Guilherme Coco, Bergo, Felipe PG, Farias, Alessandro S, Brandão, Carlos Otávio, Wildemann, Brigitte, Damasceno, Benito P, Cendes, Fernando, Santos, Leonilda M B, Yasuda, Clarissa Lin

“…Background: Although aquaporin-4 (AQP4) is widely expressed in the human brain cortex, lesions are rare in neuromyelitis optica (NMO) spectrum disorders…”
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Cytotoxic B Cells in Relapsing-Remitting Multiple Sclerosis Patients by Boldrini, Vinícius O, Marques, Ana M, Quintiliano, Raphael P S, Moraes, Adriel S, Stella, Carla R A V, Longhini, Ana Leda F, Santos, Irene, Andrade, Marília, Ferrari, Breno, Damasceno, Alfredo, Carneiro, Rafael P D, Brandão, Carlos Otávio, Farias, Alessandro S, Santos, Leonilda M B

“…Emerging evidence of antibody-independent functions, as well as the clinical efficacy of anti-CD20 depleting therapies, helped to reassess the contribution of…”
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Phenotypic changes in low-density lipoprotein particles as markers of adverse clinical outcomes in COVID-19 by Carmo, Helison Rafael P., Yoshinaga, Marcos Y., Castillo, Alejandro Rosell, Britto Chaves-Filho, Adriano, Bonilha, Isabella, Barreto, Joaquim, Muraro, Stéfanie Primon, de Souza, Gabriela Fabiano, Davanzo, Gustavo Gastão, Perroud, Maurício W., Lukhna, Kishal, Ntsekhe, Mpiko, Davidson, Sean, Velloso, Licio A., Nadruz, Wilson, Carvalho, Luiz Sérgio F., Sáinz-Jaspeado, Miguel, Farias, Alessandro S., Proença-Módena, José Luiz, Moraes-Vieira, Pedro M., Karathanasis, Sotirios K., Yellon, Derek, Miyamoto, Sayuri, Remaley, Alan T., Sposito, Andrei C.

“…Low-density lipoprotein (LDL) plasma concentration decline is a biomarker for acute inflammatory diseases, including coronavirus disease-2019 (COVID-19)…”
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Ten years of proteomics in multiple sclerosis by Farias, Alessandro S., Pradella, Fernando, Schmitt, Andrea, Santos, Leonilda M. B., Martins-de-Souza, Daniel

“…Multiple sclerosis, which is the most common cause of chronic neurological disability in young adults, is an inflammatory, demyelinating, and neurodegenerative…”
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Kinetics of peripheral blood neutrophils in severe coronavirus disease 2019 by Metzemaekers, Mieke, Cambier, Seppe, Blanter, Marfa, Vandooren, Jennifer, Carvalho, Ana Carolina, Malengier‐Devlies, Bert, Vanderbeke, Lore, Jacobs, Cato, Coenen, Sofie, Martens, Erik, Pörtner, Noëmie, Vanbrabant, Lotte, Van Mol, Pierre, Van Herck, Yannick, Van Aerde, Nathalie, Hermans, Greet, Gunst, Jan, Borin, Alexandre, Toledo N Pereira, Bruna, SP Gomes, Arilson Bernardo, Primon Muraro, Stéfanie, Fabiano de Souza, Gabriela, S Farias, Alessandro, Proenca‐Modena, José Luiz, R Vinolo, Marco Aurélio, Marques, Pedro Elias, Wouters, Carine, Wauters, Els, Struyf, Sofie, Matthys, Patrick, Opdenakker, Ghislain, Marques, Rafael Elias, Wauters, Joost, Gouwy, Mieke, Proost, Paul, Wilmer, Alexander, Meersseman, Philippe, Lambrechts, Diether, Casaer, Michael, Rex, Steffen, Lorent, Nathalie, Thevissen, Karin, Martinod, Kim

“…Objectives Emerging evidence of dysregulation of the myeloid cell compartment urges investigations on neutrophil characteristics in coronavirus disease 2019…”
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Massive activity of cytotoxic cells during refractory Neuromyelitis Optica spectrum disorder by Boldrini, Vinícius O., Brandão, Carlos Otávio, Pimentel, Maria Lucia V., Vidal, Aline, Mansur, Letícia F., Quintiliano, Raphael P.S., Santos, Leonilda M.B., Farias, Alessandro S.

“…Our group is interested in the cytotoxic mechanism during autoimmune neuroinflammation. Unexpectedly, we come across a case that presents a massive enhancement…”
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Deciphering the biochemistry and identifying biomarkers to multiple sclerosis by Martins-de-Souza, Daniel, Farias, Alessandro S.

“…Multiple sclerosis is an idiopathic demyelinating disease of the CNS. Despite being extensively studied during the last decades, many molecular aspects of the…”
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Evaluation of Staphylococcus spp. in food and kitchen premises of Campinas, Brazil by Djalma Chaves, Rafael, Pradella, Fernando, Turatti, Mariana Amarante, Amaro, Emerson Clayton, da Silva, Alessandra Regina, dos Santos Farias, Alessandro, Pereira, José Luiz, Mousavi Khaneghah, Amin

“…The current study was aimed to evaluate the occurrence of Staphylococcus in institutional and domestic kitchens, as well as in meals served at child care…”
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Regulatory T cell induction during Plasmodium chabaudi infection modifies the clinical course of experimental autoimmune encephalomyelitis by Farias, Alessandro S, Talaisys, Rafael L, Blanco, Yara C, Lopes, Stefanie C P, Longhini, Ana Leda F, Pradella, Fernando, Santos, Leonilda M B, Costa, Fabio T M

“…Experimental autoimmune encephalomyelitis (EAE) is used as an animal model for human multiple sclerosis (MS), which is an inflammatory demyelinating autoimmune…”
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