Search Results - "Alessandro, Parodi"
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1
Bio-inspired engineering of cell- and virus-like nanoparticles for drug delivery
Published in Biomaterials (01-12-2017)“…The engineering of future generations of nanodelivery systems aims at the creation of multifunctional vectors endowed with improved circulation, enhanced…”
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2
The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery
Published in Nanomedicine (London, England) (01-01-2016)“…In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream where they circulate until they reach the target tissue. The ligand on…”
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Established and Emerging Strategies for Drug Delivery Across the Blood-Brain Barrier in Brain Cancer
Published in Pharmaceutics (24-05-2019)“…Brain tumors are characterized by very high mortality and, despite the continuous research on new pharmacological interventions, little therapeutic progress…”
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4
The Role of Cysteine Cathepsins in Cancer Progression and Drug Resistance
Published in International journal of molecular sciences (23-07-2019)“…Cysteine cathepsins are lysosomal enzymes belonging to the papain family. Their expression is misregulated in a wide variety of tumors, and ample data prove…”
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5
Bromelain Surface Modification Increases the Diffusion of Silica Nanoparticles in the Tumor Extracellular Matrix
Published in ACS nano (28-10-2014)“…Tumor extracellular matrix (ECM) represents a major obstacle to the diffusion of therapeutics and drug delivery systems in cancer parenchyma. This biological…”
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6
Preterm white matter injury: ultrasound diagnosis and classification
Published in Pediatric research (01-03-2020)“…White matter injury (WMI) is the most frequent form of preterm brain injury. Cranial ultrasound (CUS) remains the preferred modality for initial and sequential…”
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7
Albumin Nanovectors in Cancer Therapy and Imaging
Published in Biomolecules (Basel, Switzerland) (05-06-2019)“…Albumin nanovectors represent one of the most promising carriers recently generated because of the cost-effectiveness of their fabrication, biocompatibility,…”
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8
Cranial ultrasound findings in preterm germinal matrix haemorrhage, sequelae and outcome
Published in Pediatric research (01-03-2020)“…Germinal matrix-intraventricular haemorrhage (GMH-IVH), periventricular haemorrhagic infarction (PHI) and its complication, post-haemorrhagic ventricular…”
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9
Nanomedicine for increasing the oral bioavailability of cancer treatments
Published in Journal of nanobiotechnology (30-10-2021)“…Oral administration is an appealing route of delivering cancer treatments. However, the gastrointestinal tract is characterized by specific and efficient…”
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10
Proteomic profiling of human amnion for preterm birth biomarker discovery
Published in Scientific reports (30-11-2021)“…Spontaneous preterm birth (PTB) complicates about 12% of pregnancies worldwide, remaining the main cause of neonatal morbidity and mortality. Spontaneous…”
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11
Anticancer Nanotherapeutics in Clinical Trials: The Work behind Clinical Translation of Nanomedicine
Published in International journal of molecular sciences (01-11-2022)“…The ultimate goal of nanomedicine has always been the generation of translational technologies that can ameliorate current therapies. Cancer disease…”
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12
Anemia in patients with Covid-19: pathogenesis and clinical significance
Published in Clinical and experimental medicine (01-05-2021)“…COVID-19 patients typically present with lower airway disease, although involvement of other organ systems is usually the rule. Hematological manifestations…”
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13
State-of-the-art neonatal cerebral ultrasound: technique and reporting
Published in Pediatric research (01-03-2020)“…In the past three decades, cerebral ultrasound (CUS) has become a trusted technique to study the neonatal brain. It is a relatively cheap, non-invasive,…”
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14
One-pot synthesis of pH-responsive hybrid nanogel particles for the intracellular delivery of small interfering RNA
Published in Biomaterials (01-05-2016)“…Abstract This report describes a novel, one-pot synthesis of hybrid nanoparticles formed by a nanostructured inorganic silica core and an organic pH-responsive…”
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Quantitative susceptibility map analysis in preterm neonates with germinal matrix‐intraventricular hemorrhage
Published in Journal of magnetic resonance imaging (01-11-2018)“…Background Germinal matrix‐intraventricular hemorrhage (GMH‐IVH) is a common form of intracranial hemorrhage occurring in preterm neonates that may affect…”
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Regional impairment of cortical and deep gray matter perfusion in preterm neonates with low-grade germinal matrix-intraventricular hemorrhage: an ASL study
Published in Neuroradiology (01-12-2020)“…Purpose The long-term impact of low-grade germinal matrix-intraventricular hemorrhage (GMH-IVH) on brain perfusion has not been fully investigated. We aimed to…”
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17
Cathepsin K in Pathological Conditions and New Therapeutic and Diagnostic Perspectives
Published in International journal of molecular sciences (09-11-2022)“…Cathepsin K (CatK) is a part of the family of cysteine proteases involved in many important processes, including the degradation activity of collagen 1 and…”
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18
Bioactive peptides: an alternative therapeutic approach for cancer management
Published in Frontiers in immunology (2024)“…Cancer is still considered a lethal disease worldwide and the patients' quality of life is affected by major side effects of the treatments including…”
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New Advances in the Understanding of Proteases as Diagnostic and Pharmaceutical Targets in Homeostatic and Pathologic Conditions
Published in Pharmaceutics (21-07-2022)“…Protease biology represents a hot topic in biomedical research because of their pivotal role in regulating cell and tissue homeostasis, regeneration and…”
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Basic Guide for Approaching Drug Delivery with Extracellular Vesicles
Published in International journal of molecular sciences (01-10-2024)“…Extracellular vesicles (EVs) are natural carriers of biomolecules that play a crucial role in cell-to-cell communication and tissue homeostasis under normal…”
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