Search Results - "Alessandro, Cappetta"

Molecular profile and its clinical impact of IDH1 mutated versus IDH1 wild type intrahepatic cholangiocarcinoma by Rimini, Margherita, Fabregat-Franco, Carles, Burgio, Valentina, Lonardi, Sara, Niger, Monica, Scartozzi, Mario, Rapposelli, Ilario Giovanni, Aprile, Giuseppe, Ratti, Francesca, Pedica, Federica, Verdaguer, Helena, Rizzato, Mario, Nichetti, Federico, Lai, Eleonora, Cappetta, Alessandro, Macarulla, Teresa, Fassan, Matteo, De Braud, Filippo, Pretta, Andrea, Simionato, Francesca, De Cobelli, Francesco, Aldrighetti, Luca, Fornaro, Lorenzo, Cascinu, Stefano, Casadei-Gardini, Andrea

“…IDH1 -mutated cholangiocarcinomas (CCAs) are an interesting group of neoplasia with particular behavior and therapeutic implications. The aim of the present…”
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Advanced gastric cancer (GC) and cancer of the gastro-oesophageal junction (GEJ): focus on targeted therapies by Cappetta, Alessandro, Lonardi, Sara, Pastorelli, Davide, Bergamo, Francesca, Lombardi, Giuseppe, Zagonel, Vittorina

“…Abstract Despite recent improvements in surgical techniques and chemotherapy treatments, locally advanced/metastatic gastroesophageal junction (GEJ) and…”
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Colorectal Cancer Heterogeneity and the Impact on Precision Medicine and Therapy Efficacy by Rosati, Gerardo, Aprile, Giuseppe, Colombo, Alfredo, Cordio, Stefano, Giampaglia, Marianna, Cappetta, Alessandro, Porretto, Concetta Maria, De Stefano, Alfonso, Bilancia, Domenico, Avallone, Antonio

“…Novel targeted therapies for metastatic colorectal cancer are needed to personalize treatments by guiding specific biomarkers selected on the genetic profile…”
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Neoplastic Meningitis from Solid Tumors: New Diagnostic and Therapeutic Approaches by Lombardi, Giuseppe, Zustovich, Fable, Farina, Patrizia, Della Puppa, Alessandro, Manara, Renzo, Cecchin, Diego, Brunello, Antonella, Cappetta, Alessandro, Zagonel, Vittorina

“…Learning Objectives After completing this course, the reader will be able to: Compare the use of i.t. therapy and systemic therapies for patients with…”
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Phase II study of neoadjuvant gemcitabine, pegylated liposomal doxorubicin, and docetaxel in locally advanced breast cancer by Artioli, Grazia, Grazia, Artioli, Mocellin, Simone, Simone, Mocellin, Borgato, Lucia, Lucia, Borgato, Cappetta, Alessandro, Alessandro, Cappetta, Bozza, Fernando, Fernando, Bozza, Zavagno, Giorgio, Giorgio, Zavagno, Zovato, Stefania, Stefania, Zovato, Marchet, Alberto, Alberto, Marchet, Pastorelli, Davide, Davide, Pastorelli

“…This was a phase II study to assess the activity of a novel neoadjuvant regimen in locally-advanced breast cancer. Fifty patients with histological…”
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Hepatoid Adenocarcinoma of the Colon: What Should We Target? by Cappetta, Alessandro, Bergamo, Francesca, Mescoli, Claudia, Lonardi, Sara, Rugge, Massimo, Zagonel, Vittorina

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A nurse-led telephone triage for the prevention and control of COVID-19 spread in an oncology department by Calvetti, Lorenzo, Simionato, Francesca, Cappetta, Alessandro, La Russa, Francesca, Cimenton, Roberta, Gasparin, Barbara, Corà, Francesco, Aprile, Giuseppe

“…Abstract only e13617 Background: After the results of the Nurse-led Telephone Triage (NTT) study ( Calvetti L, et al. ASCO 2020), the system has been…”
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Negative hyperselection and mechanisms of acquired resistance to first-line chemotherapy plus anti-EGFR in patients (pts) with pMMR RAS/BRAF wild-type (wt) metastatic colorectal cancer (mCRC): A translational analysis of the TRIPLETE trial by Conca, Veronica, Carullo, Martina, Vignali, Paola, Rossini, Daniele, Germani, Marco Maria, Bergamo, Francesca, Pietrantonio, Filippo, Borelli, Beatrice, Marmorino, Federica, Giordano, Mirella, Randon, Giovanni, Taravella, Ada, Cerantola, Riccardo, Cappetta, Alessandro, Buonadonna, Angela, Zaniboni, Alberto, Antonuzzo, Lorenzo, Masi, Gianluca, Ugolini, Clara, Cremolini, Chiara

“…3572 Background: Anti-EGFRs plus doublets are the standard first-line treatment for patients with left-sided RAS/BRAFwt mCRC. Anti-EGFR sensitivity seems…”
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Clinical outcome and safety profile of metastatic pancreatic cancer patients treated with more than six cycles of nab-paclitaxel plus gemcitabine by D'Angelo, Alberto, Catalano, Martina, Conca, Raffaele, Petrioli, Roberto, Siminonato, Francesca, Cappetta, Alessandro, Roviello, Giandomenico, Ramello, Monica

“…The phase III MPACT trial demonstrated the superiority of gemcitabine plus nab-paclitaxel (NABGEM) versus gemcitabine alone in previously untreated patients…”
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Implementation of a MSRE ddPCR method for the detection of methylated WIF1 and NPY genes in colorectal cancer patients by Trentin, Luca, Basile, Debora, Lazzari, Elena, Fietta, Elena, Rossi, Alice, Graziani, Filomena, Cappetta, Alessandro, Simionato, Francesca, D’Amore, Emanuele, Perbellini, Omar, Aprile, Giuseppe

“…Background: Colorectal cancer is a worldwide leading cause of death accounting for high-rate mortality. Mutations in the epidermal growth factor receptor and…”
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Next-generation sequencing analysis of cholangiocarcinoma identifies distinct IDH1-mutated clusters by Rimini, Margherita, Loi, Eleonora, Fabregat-Franco, Carles, Burgio, Valentina, Lonardi, Sara, Niger, Monica, Scartozzi, Mario, Raposelli, Ilario G., Aprile, Giuseppe, Ratti, Francesca, Pedica, Federica, Verdaguer, Helena, Rizzato, Mario, Nichetti, Federico, Lai, Eleonora, Cappetta, Alessandro, Macarulla, Teresa, Fassan, Matteo, De Braud, Filippo, Pretta, Andrea, Simionato, Francesca, De Cobelli, Francesco, Aldrighetti, Luca, Fornaro, Lorenzo, Cascinu, Stefano, Zavattari, Patrizia, Casadei-Gardini, Andrea

“…IDH1-mutated intrahepatic cholangiocarcinomas (IDH1m iCCAs) could be treated with anti-IDH1 drugs, although the high heterogeneity in this class of tumours…”
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From bench to bedside and back: prognostic groups of Phase 2 study of second-line FOLFIRI-aflibercept in prospectively stratified, RAS wild type, anti-EGFR resistant, metastatic colorectal cancer patients: The DISTINCTIVE trial—A GISCAD study by Lai, Eleonora, Murgioni, Sabina, Ziranu, Pina, Aprile, Giuseppe, Zaniboni, Alberto, Pretta, Andrea, Nappo, Floriana, Mosconi, Stefania, Bittoni, Alessandro, Squadroni, Michela, Cappetta, Alessandro, Daniel, Francesca, Mascia, Luigi, Rosati, Gerardo, Zampino, M. Giulia, Gelsomino, Fabio, Simionato, Francesca, Rofei, Michela, Pella, Nicoletta, Scartozzi, Mario

“…e15571 Background: Currently, no validated biomarkers are available for second-line anti-angiogenic treatment in RAS wild type (wt) metastatic colorectal…”
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Gene mutational profile of BRCAness and clinical implication in predicting response to platinum-based chemotherapy in patients with intrahepatic cholangiocarcinoma by Rimini, Margherita, Macarulla, Teresa, Burgio, Valentina, Lonardi, Sara, Niger, Monica, Scartozzi, Mario, Rapposelli, Ilario G., Aprile, Giuseppe, Ratti, Francesca, Pedica, Federica, Verdaguer, Helena, Nappo, Floriana, Nichetti, Federico, Lai, Eleonora, Valgiusti, Martina, Cappetta, Alessandro, Fabregat-Franco, Carles, Fassan, Matteo, De Braud, Filippo, Puzzoni, Marco, Frassineti, Giovanni L., Simionato, Francesca, De Cobelli, Francesco, Aldrighetti, Luca, Fornaro, Lorenzo, Cascinu, Stefano, Casadei-Gardini, Andrea

“…Background and Aims: Biliary tract cancers are rare malignancies with a poor prognosis and scarce therapeutic strategies. The significance of BRCAness in this…”
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Pattern of recurrence and overall survival in esophagogastric cancer after perioperative FLOT and clinical outcomes in MSI-H population: the PROSECCO Study by Nappo, Floriana, Fornaro, Lorenzo, Pompella, Luca, Catanese, Silvia, Lavacchi, Daniele, Spallanzani, Andrea, Cappetta, Alessandro, Puzzoni, Marco, Murgioni, Sabina, Barsotti, Giulia, Tirino, Giuseppe, Pellino, Antonio, Vivaldi, Caterina, Strippoli, Antonia, Aprile, Giuseppe, Di Donato, Samantha, Mazza, Elena, Prisciandaro, Michele, Antonuzzo, Lorenzo, Zagonel, Vittorina, Cascinu, Stefano, De Vita, Ferdinando, Lonardi, Sara

“…Background FLOT regimen is the standard perioperative treatment in Western countries for patients with locally advanced gastric (GC) or gastroesophageal…”
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FOLFOXIRI plus bevacizumab and atezolizumab as upfront treatment of unresectable metastatic colorectal cancer (mCRC): Updated and overall survival results of the phase II randomized AtezoTRIBE study by Antoniotti, Carlotta, Rossini, Daniele, Pietrantonio, Filippo, Salvatore, Lisa, Marmorino, Federica, Ambrosini, Margherita, Lonardi, Sara, Bensi, Maria, Moretto, Roberto, Tamberi, Stefano, Toma, Ilaria, Passardi, Alessandro, De Grandis, Maria Caterina, Conca, Veronica, Palermo, Federica, Cappetta, Alessandro, Catteau, Aurelie, Boni, Luca, Galon, Jérôme, Cremolini, Chiara

“…3500 Background: AtezoTRIBE (NCT03721653) is a phase II randomized trial in which unresectable mCRC pts were randomized 1:2 to 1 st -line FOLFOXIRI/bev [arm A]…”
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Platinum sensitivity in patients with IDH1/2 mutated vs wild‐type intrahepatic cholangiocarcinoma: A propensity score‐based study by Niger, Monica, Nichetti, Federico, Casadei‐Gardini, Andrea, Rizzato, Mario Domenico, Pircher, Chiara, Bini, Marta, Franza, Andrea, Rimini, Margherita, Burgio, Valentina, Sposetti, Caterina, Fornaro, Lorenzo, Rapposelli, Ilario Giovanni, D'Amico, Francesco Enrico, Aprile, Giuseppe, Vivaldi, Caterina, Frassineti, Giovanni Luca, Milione, Massimo, Leoncini, Giuseppe, Cappetta, Alessandro, Vasile, Enrico, Fassan, Matteo, Morano, Federica, Perrone, Federica, Tamborini, Elena, Pruneri, Giancarlo, Lonardi, Sara, Mazzaferro, Vincenzo, Pietrantonio, Filippo, Di Bartolomeo, Maria, de Braud, Filippo

“…Isocitrate dehydrogenase (IDH)1/2 mutations are the most frequent druggable alterations in intrahepatic cholangiocarcinoma (iCCA), reported in ~20% of cases…”
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Corrigendum to ‘Gene mutational profile of BRCAness and clinical implication in predicting response to platinum-based chemotherapy in patients with intrahepatic cholangiocarcinoma’ [Euro J Cancer 171 (2022) 232–241] by Rimini, Margherita, Macarulla, Teresa, Burgio, Valentina, Lonardi, Sara, Niger, Monica, Scartozzi, Mario, Rapposelli, Ilario G., Aprile, Giuseppe, Ratti, Francesca, Pedica, Federica, Verdaguer, Helena, Nappo, Floriana, Nichetti, Federico, Lai, Eleonora, Valgiusti, Martina, Cappetta, Alessandro, Fabregat-Franco, Carles, Fassan, Matteo, De Braud, Filippo, Puzzoni, Marco, Frassineti, Giovanni L., Simionato, Francesca, De Cobelli, Francesco, Aldrighetti, Luca, Fornaro, Lorenzo, Cascinu, Stefano, Casadei-Gardini, Andrea

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Pattern of recurrence and overall survival in esophagogastric cancer after perioperative FLOT and Clinical Outcomes in MSI-H population: The PROSECCO Study by Nappo, Floriana, Pellino, Antonio, Pompella, Luca, Catanese, Silvia, Lavacchi, Daniele, Spallanzani, Andrea, Cappetta, Alessandro, Lai, Eleonora, Murgioni, Sabina, Tirino, Giuseppe, Vivaldi, Caterina, Strippoli, Antonia, Di Donato, Samantha, Mazza, Elena, Prisciandaro, Michele, Antonuzzo, Lorenzo, Fornaro, Lorenzo, Cascinu, Stefano, De Vita, Ferdinando, Lonardi, Sara

“…e16068 Background: The FLOT4-AIO phase II/III trial established perioperative FLOT regimen as the new standard in Western countries for patients (pts) with…”
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The genomic landscape of IDH1 mutant intrahepatic cholangiocarcinoma: a multicentre comprehensive analysis by Rimini, Margherita, Macarulla, Teresa Mercade, Burgio, Valentina, Lonardi, Sara, Niger, Monica, Scartozzi, Mario, Raposelli, Ilario, Aprile, Giuseppe, Ratti, Francesca, Pedica, Federica, Verdaguer, Helena, Nappo, Floriana, Nichetti, Federico, Lai, Eleonora, Valgiusti, Martina, Cappetta, Alessandro, Fabregat, Carles, Fassan, Matteo, De Braud, Filippo, Puzzoni, Marco, Frassineti, Giovanni Luca, Simionato, Francesca, De Cobelli, Francesco, Aldrighetti, Luca, Fornaro, Lorenzo, Cascinu, Stefano, Gardini, Andrea Casadei

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Gene mutational profile of BRCAness and clinical implication in predicting response to platinum-based chemotherapy in patients with intrahepatic cholangiocarcinoma by Rimini, Margherita, Macarulla, Teresa, Burgio, Valentina, Lonardi, Sara, Niger, Monica, Scartozzi, Mario, Rapposelli, Ilario G, Aprile, Giuseppe, Ratti, Francesca, Pedica, Federica, Verdaguer, Helena, Nappo, Floriana, Nichetti, Federico, Lai, Eleonora, Valgiusti, Martina, Cappetta, Alessandro, Fabregat-Franco, Carles, Fassan, Matteo, De Braud, Filippo, Puzzoni, Marco, Frassineti, Giovanni L, Simionato, Francesca, De Cobelli, Francesco, Aldrighetti, Luca, naro, Lorenzo, Cascinu, Stefano, Casadei-Gardin, Andrea

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