Search Results - "Alemi, Mobina"

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    Transthyretin stability is critical in assisting beta amyloid clearance– Relevance of transthyretin stabilization in Alzheimer's disease by Alemi, Mobina, Silva, Sara C., Santana, Isabel, Cardoso, Isabel

    Published in CNS neuroscience & therapeutics (01-07-2017)
    “…Summary Background The absence of transthyretin (TTR) in AD mice decreases brain Aβ clearance and reduces the low‐density lipoprotein receptor‐related protein…”
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    Journal Article
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    Exploring the Physiological Role of Transthyretin in Glucose Metabolism in the Liver by Alemi, Mobina, Oliveira, Ângela, Tavares, Sofia C., Vieira, José Ricardo, Alves, Marco G., Oliveira, Pedro F., Cardoso, Isabel

    “…Transthyretin (TTR), a 55 kDa evolutionarily conserved protein, presents altered levels in several conditions, including malnutrition, inflammation, diabetes,…”
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    Resveratrol administration increases Transthyretin protein levels ameliorating AD features- importance of transthyretin tetrameric stability by Santos, L M, Rodrigues, D, Alemi, M, Silva, S C, Ribeiro, C A, Cardoso, I

    Published in Molecular medicine (Cambridge, Mass.) (01-01-2016)
    “…Previous in vivo work showed that resveratrol has beneficial effects in the AD pathology, resulting in increased expression of transthyretin (TTR). TTR binds…”
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    Dynamics of Lateral Habenula–Ventral Tegmental Area Microcircuit on Pain-Related Cognitive Dysfunctions by Pereira, Ana Raquel, Alemi, Mobina, Cerqueira-Nunes, Mariana, Monteiro, Clara, Galhardo, Vasco, Cardoso-Cruz, Helder

    Published in Neurology international (01-10-2023)
    “…Chronic pain is a health problem that affects the ability to work and perform other activities, and it generally worsens over time. Understanding the complex…”
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    Role of Glutamatergic Projections from Lateral Habenula to Ventral Tegmental Area in Inflammatory Pain-Related Spatial Working Memory Deficits by Alemi, Mobina, Pereira, Ana Raquel, Cerqueira-Nunes, Mariana, Monteiro, Clara, Galhardo, Vasco, Cardoso-Cruz, Helder

    Published in Biomedicines (01-03-2023)
    “…The lateral habenula (LHb) and the ventral tegmental area (VTA), which form interconnected circuits, have important roles in the crucial control of sensory and…”
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    Journal Article
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    Anti-inflammatory Effect of Seeds and Callus of Nigella sativa L. Extracts on Mix Glial Cells with Regard to Their Thymoquinone Content by Alemi, Mobina, Sabouni, Farzaneh, Sanjarian, Forough, Haghbeen, Kamahldin, Ansari, Saeed

    Published in AAPS PharmSciTech (01-03-2013)
    “…Anti-inflammatory effect of the alcoholic extracts of N. sativa seeds and its callus on mix glial cells of rat with regard to their thymoquinone (TQ) content…”
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    The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation by Cristóvão, Joana S, Morris, Vanessa K, Cardoso, Isabel, Leal, Sónia S, Martínez, Javier, Botelho, Hugo M, Göbl, Christoph, David, Rodrigo, Kierdorf, Katrin, Alemi, Mobina, Madl, Tobias, Fritz, Günter, Reif, Bernd, Gomes, Cláudio M

    Published in Science advances (01-06-2018)
    “…Amyloid-β (Aβ) aggregation and neuroinflammation are consistent features in Alzheimer's disease (AD) and strong candidates for the initiation of…”
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    Journal Article