Tissue Damage, Temperature, and pH Induced by Different Electrode Arrays on Potato Pieces ( Solanum tuberosum L.)

One of the most challenging problems of electrochemical therapy is the design and selection of suitable electrode array for cancer. The aim is to determine how two-dimensional spatial patterns of tissue damage, temperature, and pH induced in pieces of potato ( L., var. Mondial) depend on electrode a...

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Published in:Frontiers in oncology Vol. 8; p. 101
Main Authors: González, Maraelys Morales, Aguilar, Claudia Hernández, Pacheco, Flavio Arturo Domínguez, Cabrales, Luis Enrique Bergues, Reyes, Juan Bory, Nava, Juan José Godina, Ambrosio, Paulo Eduardo, Domiguez, Dany Sanchez, Sierra González, Victoriano Gustavo, Pupo, Ana Elisa Bergues, Ciria, Héctor Manuel Camué, Alemán, Elizabeth Issac, García, Francisco Monier, Rivas, Clara Berenguer, Reina, Evelyn Chacón
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 19-04-2018
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Summary:One of the most challenging problems of electrochemical therapy is the design and selection of suitable electrode array for cancer. The aim is to determine how two-dimensional spatial patterns of tissue damage, temperature, and pH induced in pieces of potato ( L., var. Mondial) depend on electrode array with circular, elliptical, parabolic, and hyperbolic shape. The results show the similarity between the shapes of spatial patterns of tissue damage and electric field intensity, which, like temperature and pH take the same shape of electrode array. The adequate selection of suitable electrodes array requires an integrated analysis that involves, in a unified way, relevant information about the electrochemical process, which is essential to perform more efficiently way the therapeutic planning and the personalized therapy for patients with a cancerous tumor.
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Reviewed by: Marcos Tello, IEEE The Institute of Electrical and Electronics Engineers, Brazil; Ugo Carraro, Università degli Studi di Padova, Italy
Specialty section: This article was submitted to Molecular and Cellular Oncology, a section of the journal Frontiers in Oncology
Edited by: Cecilia Ana Suarez, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2018.00101