Search Results - "Aleksova, Aneta"
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The peculiar role of vitamin D in the pathophysiology of cardiovascular and neurodegenerative diseases
Published in Life sciences (1973) (15-01-2022)“…Vitamin D is a hormone with both genomic and non-genomic actions. It exerts its activity by binding vitamin D receptor (VDR), which belongs to the superfamily…”
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Effects of SARS-CoV-2 on Cardiovascular System: The Dual Role of Angiotensin-Converting Enzyme 2 (ACE2) as the Virus Receptor and Homeostasis Regulator-Review
Published in International journal of molecular sciences (26-04-2021)“…Angiotensin-converting enzyme 2 (ACE2) is the entry receptor for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of Coronavirus…”
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From Brain to Heart: Possible Role of Amyloid-β in Ischemic Heart Disease and Ischemia-Reperfusion Injury
Published in International journal of molecular sciences (17-12-2020)“…Ischemic heart disease (IHD) is among the leading causes of death in developed countries. Its pathological origin is traced back to coronary atherosclerosis, a…”
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Subcellular Effectors of Cocaine Cardiotoxicity: All Roads Lead to Mitochondria-A Systematic Review of the Literature
Published in International journal of molecular sciences (25-09-2023)“…Cocaine abuse is a serious public health problem as this drug exerts a plethora of functional and histopathological changes that potentially lead to death…”
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Traditional and Emerging Biomarkers in Asymptomatic Left Ventricular Dysfunction—Promising Non-Coding RNAs and Exosomes as Biomarkers in Early Phases of Cardiac Damage
Published in International journal of molecular sciences (01-05-2021)“…Heart failure (HF) is one of the major causes of morbidity and mortality worldwide and represents an escalating problem for healthcare systems. The…”
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Old and Novel Therapeutic Approaches in the Management of Hyperglycemia, an Important Risk Factor for Atherosclerosis
Published in International journal of molecular sciences (20-02-2022)“…Hyperglycemia is considered one of the main risk factors for atherosclerosis, since high glucose levels trigger multiple pathological processes, such as…”
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Extracellular Vesicles: How Drug and Pathology Interfere With Their Biogenesis and Function
Published in Frontiers in physiology (01-10-2018)“…Extracellular vesicles (EV) are at the center of an intense activity of investigation, both for their possible employment as biomarkers of ongoing pathologic…”
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Persistent left ventricular dysfunction after acute lymphocytic myocarditis: Frequency and predictors
Published in PloS one (28-03-2019)“…Persistent left ventricular (LV) systolic dysfunction in patients with acute lymphocytic myocarditis (LM) is widely unexplored. To assess the frequency and…”
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n -3 PUFA-Enriched Diet Preserves Skeletal Muscle Mitochondrial Function and Redox State and Prevents Muscle Mass Loss in Mice with Chronic Heart Failure
Published in Nutrients (11-07-2023)“…Skeletal muscle derangements, potentially including mitochondrial dysfunction with altered mitochondrial dynamics and high reactive oxygen species (ROS)…”
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The Role of Exercise-Induced Molecular Processes and Vitamin D in Improving Cardiorespiratory Fitness and Cardiac Rehabilitation in Patients With Heart Failure
Published in Frontiers in physiology (11-01-2022)“…Heart failure (HF) still affects millions of people worldwide despite great advances in therapeutic approaches in the cardiovascular field. Remarkably, unlike…”
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BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice
Published in Cell death & disease (15-08-2023)“…Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a…”
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What the Cardiologist Needs to Consider in the Management of Oncologic Patients with STEMI-Like Syndrome: A Case Report and Literature Review
Published in Pharmaceuticals (Basel, Switzerland) (01-06-2021)“…In pre-hospital care, an accurate and quick diagnosis of ST-segment elevation myocardial infarction (STEMI) is imperative to promptly kick-off the STEMI…”
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Preserved Skeletal Muscle Mitochondrial Function, Redox State, Inflammation and Mass in Obese Mice with Chronic Heart Failure
Published in Nutrients (04-11-2020)“…: Skeletal muscle (SM) mitochondrial dysfunction, oxidative stress, inflammation and muscle mass loss may worsen prognosis in chronic heart failure (CHF)…”
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Biomarkers in the management of acute heart failure: state of the art and role in COVID‐19 era
Published in ESC Heart Failure (01-12-2021)“…Acute heart failure (AHF) affects millions of people worldwide, and it is a potentially life‐threatening condition for which the cardiologist is more often…”
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Autophagy and Inflammasome Activation in Dilated Cardiomyopathy
Published in Journal of clinical medicine (21-09-2019)“…Background: The clinical outcome of patients affected by dilated cardiomyopathy (DCM) is heterogeneous, since its pathophysiology is only partially understood…”
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Differential Role of Circulating microRNAs to Track Progression and Pre-Symptomatic Stage of Chronic Heart Failure: A Pilot Study
Published in Biomedicines (11-12-2020)“…(1)Background: Chronic heart failure (CHF) contributes to the overall burden of cardiovascular disease. Early identification of at-risk individuals may…”
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COVID-19-Related Myocarditis: Are We There Yet? A Case Report of COVID-19-Related Fulminant Myocarditis
Published in Biomedicines (01-07-2023)“…There is increasing evidence of cardiac involvement in COVID-19 cases, with a broad range of clinical manifestations spanning from acute life-threatening…”
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Critical role of lysosomes in the dysfunction of human Cardiac Stem Cells obtained from failing hearts
Published in International journal of cardiology (01-08-2016)“…Abstract The in vivo reparative potential of Cardiac Stem Cells (CSC), cultured from explanted failing hearts (E-), is impaired by cellular senescence…”
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Common Shared Pathogenic Aspects of Small Vessels in Heart and Brain Disease
Published in Biomedicines (27-04-2022)“…Small-vessel disease (SVD), also known as microvascular endothelial dysfunction, is a disorder with negative consequences for various organs such as the heart…”
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HOMA-IR as a Predictor of PAI-1 Levels in Women with Severe Obesity
Published in Biomedicines (31-05-2024)“…Obesity is a chronic inflammatory disorder that increases the risk of cardiovascular diseases (CVDs). Given the high CVD mortality rate among individuals with…”
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