Search Results - "Alekseeva, I. A."
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Morphological and molecular-biological features of glioblastoma progression in tolerant and susceptible to hypoxia Wistar rats
Published in Scientific reports (04-08-2023)“…Hypoxia is a major pathogenetic factor in many cancers. Individual resistance to suboptimal oxygen availability is subject to broad variation and its possible…”
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Quantification of attenuation and speckle features from endoscopic OCT images for the diagnosis of human brain glioma
Published in Scientific reports (10-05-2024)“…Application of optical coherence tomography (OCT) in neurosurgery mostly includes the discrimination between intact and malignant tissues aimed at the…”
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3
Quantitative polarization-sensitive super-resolution solid immersion microscopy reveals biological tissues’ birefringence in the terahertz range
Published in Scientific reports (03-10-2023)“…Terahertz (THz) technology offers a variety of applications in label-free medical diagnosis and therapy, majority of which rely on the effective medium theory…”
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4
Characteristics of the Antitumor Effect of Doxorubicin and Pegylated Hyaluronidase on Models of Rat Brain Tumors
Published in Bulletin of experimental biology and medicine (01-05-2024)“…Hyaluronidase increases tissue permeability and diffusion of the extracellular fluid by cleaving hyaluronan, the primary component of the extracellular matrix…”
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Comparative Morphological and Molecular Genetic Characteristics of Cell and Tissue Strains of Experimental Rat Glioma 10-17-2 (Astrid-17)
Published in Bulletin of experimental biology and medicine (01-05-2024)“…In order to obtain models of gliomas of varying degrees of malignancy, we performed morphological and molecular genetic study of a tissue strain of glioma…”
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The Effect of Therapy Regimen on Antitumor Efficacy of the Nanosomal Doxorubicin against Rat Glioblastoma 101.8
Published in Bulletin of experimental biology and medicine (01-03-2024)“…One of the key problems of glioblastoma treatment is the low effectiveness of chemotherapeutic drugs. Incorporation of doxorubicin into PLGA nanoparticles…”
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Gene Expression Profile of 3D Spheroids in Comparison with 2D Cell Cultures and Tissue Strains of Diffuse High-Grade Gliomas
Published in Bulletin of experimental biology and medicine (01-08-2023)“…The use of relevant, accessible, and easily reproducible preclinical models of diffuse gliomas is a prerequisite for the development of successful therapeutic…”
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Changes in Oncogene Expression in Experimental Glioblastoma 101.8 Rats during Therapy with PLGA Nanoparticles Loaded with Doxorubicin
Published in Bulletin of experimental biology and medicine (01-02-2023)“…We compared the expression of the main glioblastoma oncogenes during therapy with doxorubicin (Dox) and Dox in nanoparticles based on a copolymer of lactic and…”
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Terahertz dielectric spectroscopy and solid immersion microscopy of ex vivo glioma model 101.8: brain tissue heterogeneity
Published in Biomedical optics express (01-08-2021)“…Terahertz (THz) technology holds strong potential for the intraoperative label-free diagnosis of brain gliomas, aimed at ensuring their gross-total resection…”
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Carbon Nanodots Obtained by Microwave Synthesis: Physical Properties and Assessment of Cytotoxicity on a Model of Glioblastoma and Embryonal Kidney In Vitro
Published in Physics of atomic nuclei (01-12-2023)“…Carbon nanodots (CNDs) produced by liquid-based synthesis methods are an example of a biocompatible, nontoxic nanomaterial with physical properties promising…”
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Features of using of a fixed combination of rosuvastatin and ezetimibe for effective hypolipidemic therapy
Published in Medicinskij sovet (15-10-2020)“…Mortality from cardiovascular diseases (CVD) in Russian Federation (RF) remains one of the highest in the world. Compared to 2003, the mortality from CVD…”
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Capability of physically reasonable OCT-based differentiation between intact brain tissues, human brain gliomas of different WHO grades, and glioma model 101.8 from rats
Published in Biomedical optics express (01-11-2020)“…Optical coherence tomography (OCT) of the ex vivo rat and human brain tissue samples is performed. The set of samples comprises intact white and gray matter,…”
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13
Atorvastatin: old friend in the light of novel coronavirus infection’s pandemia
Published in Medicinskij sovet (06-04-2022)“…The COVID-19 (COronaVIrus Disease 2019) pandemic caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus 2) continues to be a global threat to…”
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Preparation and Crystallographic Analysis of a Complex of SARS-CoV-2 S-Protein Receptor-Binding Domain with a Virus-Neutralizing Nanoantibody
Published in Crystallography reports (01-12-2023)“…Coronavirus SARS-CoV-2 was the cause of global pandemic COVID-19 that has claimed millions of lives around the world. One of the approaches to the therapy of…”
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15
Efficiency of high-intensity therapy with rosuvastatin for secondary prevention of cardiovascular complications in patients with a very high risk
Published in Aterotromboz (Online) (21-01-2022)“…According to the latest international and Russian guidelines for the treatment of dyslipidemias, statins are defined as the main group of drugs that…”
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16
A method for calculating the acid–base equilibria in aqueous and nonaqueous electrolyte solutions
Published in Russian Journal of Physical Chemistry A (01-06-2017)“…Concentrations of particles in acid–base equilibria in aqueous and nonaqueous solutions of electrolytes are calculated on the basis of logarithmic charts,…”
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Combination of nanosomal form of doxorubicin, interferon alpha, and nitroglycerin in the threatment of 101.8 glioblastoma in Wistar rats
Published in Antibiotiki i himioterapiâ (02-01-2022)“…The search for effective approaches to the treatment of patients with glioblastoma is one of the difficult tasks of neurooncology; standard methods of therapy…”
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Covalently conjugated DNA aptamer with doxorubicin as in vitro model for effective targeted drug delivery to human glioblastoma tumor cells
Published in Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko (2024)“…Targeted delivery of chemotherapeutic agents with aptamers is a very effective method increasing therapeutic index compared to non-targeted drugs. To study the…”
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Broadly Reactive Nanobody Targeting the H3 Hemagglutinin of the Influenza A Virus
Published in Actanaturae (01-01-2024)“…Monoclonal antibodies and recombinant antibody fragments are a very promising therapeutic tool to combat infectious diseases. Due to their unique paratope…”
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Fixeddose combination of rosuvastatin + ezetimibe: ease of use, safety and efficacy
Published in Medicinskij sovet (09-10-2019)“…Today, cardiovascular diseases remain the leading cause of morbidity and mortality globally. Hyperlipidemia and dyslipidemia are key points in the occurrence…”
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