Search Results - "Alejandra Barrera Jiménez, Ana"

Improvement of a 1D Population Balance Model for Twin-Screw Wet Granulation by Using Identifiability Analysis by Barrera Jiménez, Ana Alejandra, Van Hauwermeiren, Daan, Peeters, Michiel, De Beer, Thomas, Nopens, Ingmar

“…Recently, the pharmaceutical industry has undergone changes in the production of solid oral dosages from traditional inefficient and expensive batch production…”
Get full text

Exploring the effect of raw material properties on continuous twin-screw wet granulation manufacturability by Peeters, Michiel, Barrera Jiménez, Ana Alejandra, Matsunami, Kensaku, Van Hauwermeiren, Daan, Stauffer, Fanny, Arnfast, Lærke, Vigh, Tamas, Nopens, Ingmar, De Beer, Thomas

“…[Display omitted] Twin-screw wet granulation (TSWG) stands out as a promising continuous alternative to conventional batch fluid bed- and high shear wet…”
Get full text

Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation by Peeters, Michiel, Barrera Jiménez, Ana Alejandra, Matsunami, Kensaku, Ghijs, Michael, Dos Santos Schultz, Eduardo, Roudgar, Mina, Vigh, Tamas, Stauffer, Fanny, Nopens, Ingmar, De Beer, Thomas

“…In the last few years, twin-screw wet granulation (TSWG) has become one of the key continuous pharmaceutical unit operations. Despite the many studies that…”
Get full text

Model development and calibration of two-dimensional population balance model for twin-screw wet granulation based on particle size distribution and porosity by Barrera Jiménez, Ana Alejandra, Matsunami, Kensaku, Ghijs, Michael, Van Hauwermeiren, Daan, Peeters, Michiel, Stauffer, Fanny, De Beer, Thomas, Nopens, Ingmar

“…Population balance models (PBMs) have been widely studied for the simulation of continuous twin-screw wet granulation. Due to the limited data availability and…”
Get full text

Validation of model-based design of experiments for continuous wet granulation and drying by Matsunami, Kensaku, Vandeputte, Tuur, Barrera Jiménez, Ana Alejandra, Peeters, Michiel, Ghijs, Michael, Van Hauwermeiren, Daan, Stauffer, Fanny, dos Santos Schultz, Eduardo, Nopens, Ingmar, De Beer, Thomas

“…This paper presents an application case of model-based design of experiments for the continuous twin-screw wet granulation and fluid-bed drying sequence. The…”
Get full text

Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation by Barrera Jiménez, Ana Alejandra, Matsunami, Kensaku, Van Hauwermeiren, Daan, Peeters, Michiel, Stauffer, Fanny, dos Santos Schultz, Eduardo, Kumar, Ashish, De Beer, Thomas, Nopens, Ingmar

“…In the pharmaceutical industry, twin-screw wet granulation has become a realistic option for the continuous manufacturing of solid drug products. Towards the…”
Get full text

Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation by Barrera Jiménez, Ana Alejandra, Matsunami, Kensaku, Van Hauwermeiren, Daan, Peeters, Michiel, Stauffer, Fanny, dos Santos Schultz, Eduardo, Kumar, Ashish, De Beer, Thomas, Nopens, Ingmar

“…Population balance models (PBM) have been widely used to model the twin-screw wet granulation (TSWG) in the continuous manufacturing of solid dosage forms…”
Get full text

Evaluation of the influence of material properties and process parameters on granule porosity in twin-screw wet granulation by Peeters, Michiel, Alejandra Barrera Jiménez, Ana, Matsunami, Kensaku, Stauffer, Fanny, Nopens, Ingmar, De Beer, Thomas

“…[Display omitted] In recent years, continuous twin-screw wet granulation (TSWG) is gaining increasing interest from the pharmaceutical industry. Despite the…”
Get full text