Search Results - "Aleisa, Abdulaziz M."

Sleep deprivation prevents stimulation-induced increases of levels of P-CREB and BDNF: Protection by caffeine by Alhaider, Ibrahim A., Aleisa, Abdulaziz M., Tran, Trinh T., Alkadhi, Karim A.

“…It is well known that caffeine and sleep deprivation have opposing effects on learning and memory; therefore, this study was undertaken to determine the…”
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Levothyroxin restores hypothyroidism-induced impairment of hippocampus-dependent learning and memory: Behavioral, electrophysiological, and molecular studies by Alzoubi, Karem H., Gerges, Nashaat Z., Aleisa, Abdulaziz M., Alkadhi, Karim A.

“…Hypothyroidism induces cognitive impairment in experimental animals and patients. Clinical reports are conflicting about the ability of thyroid hormone…”
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Chronic Caffeine Treatment Prevents Sleep Deprivation-Induced Impairment of Cognitive Function and Synaptic Plasticity by ALHAIDER, Ibrahim A, ALEISA, Abdulaziz M, TRAN, Trinh T, ALZOUBI, Karem H, ALKADHI, Karim A

“…This study was undertaken to provide a detailed account of the effect of chronic treatment with a small dose of caffeine on the deleterious effects of sleep…”
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Progression of diethylnitrosamine-induced hepatic carcinogenesis in carnitine-depleted rats by Al-Rejaie, Salim S, Aleisa, Abdulaziz M, Al-Yahya, Abdulaziz A, Bakheet, Saleh A, Alsheikh, Abdulmalik, Fatani, Amal G, Al-Shabanah, Othman A, Sayed-Ahmed, Mohamed M

“…AIM： To investigate whether carnitine deficiency is a risk factor during the development of diethylnitrosamine （DENA）-induced hepatic carcinogenesis. METHODS：…”
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Caffeine prevents sleep loss-induced deficits in long-term potentiation and related signaling molecules in the dentate gyrus by Alhaider, Ibrahim A., Aleisa, Abdulaziz M., Tran, Trinh T., Alkadhi, Karim A.

“…We have previously reported that caffeine prevented sleep deprivation‐induced impairment of long‐term potentiation (LTP) of area CA1 as well as…”
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Thymoquinone attenuates diethylnitrosamine induction of hepatic carcinogenesis through antioxidant signaling by Sayed-Ahmed, Mohamed M, Aleisa, Abdulaziz M, Al-Rejaie, Salim S, Al-Yahya, Abdulaziz A, Al-Shabanah, Othman A, Hafez, Mohamed M, Nagi, Mahmoud N

“…Hepatocellular carcinoma accounts for about 80-90% of all liver cancer and is the fourth most common cause of cancer mortality. Although there are many…”
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Inhibition of gene expression of heart fatty acid binding protein and organic cation/carnitine transporter in doxorubicin cardiomyopathic rat model by Sayed-Ahmed, Mohamed M., Al-Shabanah, Othman A., Hafez, Mohamed M., Aleisa, Abdulaziz M., Al-Rejaie, Salem S.

“…This study examined whether doxorubicin therapy alters the expression of heart fatty acid binding protein (H-FABP) and organic cation/carnitine transporter…”
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Propionyl- l-carnitine prevents the progression of cisplatin-induced cardiomyopathy in a carnitine-depleted rat model by Al-Majed, Abdulhakeem A., Sayed-Ahmed, Mohamed M., Al-Yahya, Abdulaziz A., Aleisa, Abdulaziz M., Al-Rejaie, Salim S., Al-Shabanah, Othman A.

“…This study has been initiated to investigate whether endogenous carnitine depletion and/or carnitine deficiency is a risk factor during development of…”
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Psychosocial stress-induced hypertension results from in vivo expression of long-term potentiation in rat sympathetic ganglia by Alkadhi, Karim A., Alzoubi, Karem H., Aleisa, Abdulaziz M., Tanner, Felicia L., Nimer, Ayad S.

“…Long-term potentiation in sympathetic ganglia (gLTP) is an activity-dependent unique form of synaptic plasticity in that it is serotonin-dependent and can be…”
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REVERSAL OF CISPLATIN-INDUCED CARNITINE DEFICIENCY AND ENERGY STARVATION BY PROPIONYL-l-CARNITINE IN RAT KIDNEY TISSUES by Aleisa, Abdulaziz M, Al-Majed, Abdulhakeem A, Al-Yahya, Abdulaziz A, Al-Rejaie, Salim S, Bakheet, Saleh A, Al-Shabanah, Othman A, Sayed-Ahmed, Mohamed M

“…SUMMARY 1 The present study examined whether propionyl‐l‐carnitine (PLC) could prevent the development of cisplatin (CDDP)‐induced acute renal failure in rats…”
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Chronic nicotine restores normal Aβ levels and prevents short-term memory and E-LTP impairment in Aβ rat model of Alzheimer's disease by Srivareerat, Marisa, Tran, Trinh T, Salim, Samina, Aleisa, Abdulaziz M, Alkadhi, Karim A

“…Abstract Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by increased deposition of beta-amyloid (Aβ) peptides and…”
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CARNITINE ESTERS PREVENT OXIDATIVE STRESS DAMAGE AND ENERGY DEPLETION FOLLOWING TRANSIENT FOREBRAIN ISCHAEMIA IN THE RAT HIPPOCAMPUS by Al-Majed, Abdulhakeem A, Sayed-Ahmed, Mohamed M, Al-Omar, Fadhal A, Al-Yahya, Abdulaziz A, Aleisa, Abdulaziz M, Al-Shabanah, Othman A

“…SUMMARY 1 The present study investigated whether propionyl‐l‐carnitine (PLC) has neuroprotective effects, similar to those reported for acetyl‐l‐carnitine…”
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Naringenin neutralises oxidative stress and nerve growth factor discrepancy in experimental diabetic neuropathy by Al-Rejaie, Salim S., Aleisa, Abdulaziz M., Abuohashish, Hatem M., Parmar, Mihir Y., Ola, Mohammad S., Al-Hosaini, Abdulaziz A., Ahmed, Mohammed M.

“…Objectives: Present study aims to investigate the ameliorative effects of naringenin (NG) on experimentally induced diabetic neuropathy (DN) in rats. Methods:…”
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Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: Molecular docking study by El-Azab, Adel S., Al-Omar, Mohamed A., Abdel-Aziz, Alaa A.-M., Abdel-Aziz, Naglaa I., El-Sayed, Magda A.-A., Aleisa, Abdulaziz M., Sayed-Ahmed, Mohamed M., Abdel-Hamide, Sami G.

“…Novel derivatives of quinazoline ( 1– 27) have been synthesized and tested for their antitumor activity against three tumor cell lines among these cell lines…”
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Flavonoid, morin inhibits oxidative stress, inflammation and enhances neurotrophic support in the brain of streptozotocin-induced diabetic rats by Ola, Mohammad S., Aleisa, Abdulaziz M., Al-Rejaie, Salim S., Abuohashish, Hatem M., Parmar, Mihir Y., Alhomida, Abdullah S., Ahmed, Mohammed M.

“…Diabetes-induced damages in brain are known as diabetic encephalopathy, which is well characterized by cellular, molecular and functional changes in the brain…”
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Nicotine blocks stress-induced impairment of spatial memory and long-term potentiation of the hippocampal CA1 region by Aleisa, Abdulaziz M., Alzoubi, Karem H., Gerges, Nashaat Z., Alkadhi, Karim A.

“…The effect of chronic nicotine treatment on chronic psychosocial stress-induced impairment of short-term memory and long-term potentiation (LTP) was…”
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Possible biochemical effects following inhibition of ethanol-induced gastric mucosa damage by Gymnema sylvestre in male Wistar albino rats by Al-Rejaie, Salim S, Abuohashish, Hatem M, Ahmed, Mohammed M, Aleisa, Abdulaziz M, Alkhamees, Osama

“…Gymnema sylvestre (GS) R. Br. (Gymnema) (Asclepiadaceae) has been used from ancient times as a folk medicine for the treatment of diabetes, obesity, urinary…”
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Ameliorative Potential of Morin in Streptozotocin-Induced Neuropathic Pain in Rats by AlSharari, Shakir D, Al-Rejaie, Salim S, Abuohashish, Hatem M, Aleisa, Abdulaziz M, Parmar, Mihir Y, Ahmed, Mohammed M

“…Purpose: To investigate the protective effect of morin, a naturally occurring bioflavonoid of Moraceae family, in experimentally-induced diabetic neuropathy…”
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Telmisartan inhibits hyperalgesia and inflammatory progression in a diabetic neuropathic pain model of Wistar rats by Al-Rejaie, Salim S, Abuohashish, Hatem M, Ahmed, Mohammed M, Arrejaie, Aws S, Aleisa, Abdulaziz M, AlSharari, Shakir D

“…To evaluate the potential therapeutic value of telmisartan (TMT) against diabetic neuropathy (DN) and associated pain in Wistar rats. Peripheral DN was induced…”
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Desferrioxamine Attenuates Doxorubicin-Induced Acute Cardiotoxicity through TFG-β/Smad p53 Pathway in Rat Model by al-Shabanah, Othman A., Aleisa, Abdulaziz M., Hafez, Mohamed M., al-Rajai, Salim S., al-Yahya, Abdulaziz A., Bakheet, Saleh A., al-Harbi, Mohamed M., Sayed-Ahmed, Mohammed M.

“…Interaction of doxorubicin DOX with iron and the consequent generation of reactive oxygen species (ROS) is a major player in DOX-induced cardiomyopathy…”
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