Search Results - "Alegria, Guillermo Carvajal"

The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle by Carvajal Alegria, Guillermo, Boukhlal, Sara, Cornec, Divi, Devauchelle-Pensec, Valérie

“…Polymyalgia rheumatica (PMR) is a frequent rheumatic condition among people over 50 years of age. Despite its frequent association with giant cell arteritis…”
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Biomarkers in the era of targeted therapy in giant cell arteritis and polymyalgia rheumatica: is it possible to replace acute-phase reactants? by Carvajal Alegria, Guillermo, Nicolas, Mathilde, van Sleen, Yannick

“…Research into giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) has become more important in the last few decades. Physicians are facing several…”
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A Risk Score to Detect Subclinical Rheumatoid Arthritis–Associated Interstitial Lung Disease by Juge, Pierre‐Antoine, Granger, Benjamin, Debray, Marie‐Pierre, Ebstein, Esther, Louis‐Sidney, Fabienne, Kedra, Joanna, Doyle, Tracy J., Borie, Raphaël, Constantin, Arnaud, Combe, Bernard, Flipo, René‐Marc, Mariette, Xavier, Vittecoq, Olivier, Saraux, Alain, Carvajal‐Alegria, Guillermo, Sibilia, Jean, Berenbaum, Francis, Kannengiesser, Caroline, Boileau, Catherine, Sparks, Jeffrey A., Crestani, Bruno, Fautrel, Bruno, Dieudé, Philippe

“…Objective Patients at high risk of rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) would benefit from being identified before the onset of…”
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Treatment with Targeted Therapy in Patients with Psoriatic Arthritis and Inadequate Response to Methotrexate: Proposal for a Rational Strategy by Goupille, Philippe, Carvajal Alegria, Guillermo, Verhoeven, Frank, Wendling, Daniel

“…Introduction The therapeutic arsenal for psoriatic arthritis (PsA) is gradually being expanded, but the use of these targeted treatments must be optimal. Our…”
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Epidemiology of neurological manifestations in Sjögren's syndrome: data from the French ASSESS Cohort by Carvajal Alegria, Guillermo, Guellec, Dewi, Mariette, Xavier, Gottenberg, Jacques-Eric, Dernis, Emmanuelle, Dubost, Jean-Jacques, Trouvin, Anne-Priscille, Hachulla, Eric, Larroche, Claire, Le Guern, Veronique, Cornec, Divi, Devauchelle-Pensec, Valérie, Saraux, Alain

“…ObjectivesNeurological manifestations seem common in primary Sjögren's syndrome (pSS) but their reported prevalences vary. We investigated the prevalence and…”
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Development of a web-based ecological momentary assessment tool to measure day-to-day variability of the symptoms in patients with Sjögren’s disease by Georgel, Laurie, Benyoussef, Anas-Alexis, Berrouiguet, Sofian, Guellec, Dewi, Carvajal Alegria, Guillermo, Marhadour, Thierry, Jousse-Joulin, Sandrine, Cochener-Lamard, Béatrice, Labetoulle, Marc, Gottenberg, Jacques-Eric, Bourcier, Tristan, Nocturne, Gaétane, Saraux, Alain, Mariette, Xavier, Consigny, Maëlys, Gravey, Michel, Devauchelle-Pensec, Valérie, Seror, Raphaele, Cornec, Divi

“…ObjectivesTo develop and validate a web-based ecological momentary assessment (EMA) tool to enhance symptoms monitoring among patients with Sjögren’s disease…”
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New onset of rheumatoid vasculitis during abatacept therapy and subsequent improvement after rituximab by Carvajal Alegria, Guillermo, Uguen, Arnaud, Genestet, Steeve, Marcorelles, Pascale, Saraux, Alain, Cornec, Divi

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The pipeline of immunomodulatory therapies in polymyalgia rheumatica and giant cell arteritis: A systematic review of clinical trials by Kawka, Lou, Chevet, Baptiste, Arnaud, Laurent, Becker, Guillaume, Carvajal Alegria, Guillermo, Felten, Renaud

“…The objective of this systematic review was to provide an overview of current developments and potentially available therapeutic options for polymyalgia…”
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Efficacy of Janus kinase inhibitors in rheumatoid arthritis by Langbour, Camille, Rene, Jessica, Goupille, Philippe, Carvajal Alegria, Guillermo

“…Background Janus kinase inhibitors (JAKis) is a new therapeutic class in autoimmune and inflammatory diseases. Four molecules are approved in rheumatoid…”
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Fibroblasts, a target for imaging and therapeutics in rheumatoid arthritis by Carvajal Alegria, Guillermo, Croft, Adam P

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Against the dryness—an innovative 3D acini model to test new drugs in primary Sjögren’s syndrome by Carvajal Alegria, Guillermo, Cornec, Divi

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Prevalence and predictors of atlanto-axial subluxation in rheumatoid arthritis after 12-years’ follow-up (ESPOIR Cohort) by Le Quellec, Aurore, Guyard, Thibaut, Carvajal Alegria, Guillermo, Ruyssen-Witrand, Adeline, Fautrel, Bruno, Flipo, René Marc, Garrigues, Florent, Saraux, Alain

“…Abstract Objectives Anterior atlanto-axial subluxation (AAS), defined as an anterior atlanto-dental interval ≥3 mm, can occur in RA and carries a risk of…”
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Abatacept Promotes Regulatory B Cell Functions, Enhancing Their Ability to Reduce the Th1 Response in Rheumatoid Arthritis Patients through the Production of IL-10 and TGF-β by Carvajal Alegria, Guillermo, Cornec, Divi, Saraux, Alain, Devauchelle-Pensec, Valérie, Jamin, Christophe, Hillion, Sophie, Pers, Jacques-Olivier, Pochard, Pierre

“…Abatacept mimics natural CD152 and competes with CD28 for binding to CD80/CD86 on APC, such as B cells, thereby preventing T cell activation. However, its…”
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Is Tocilizumab as efficient as steroids early in polymyalgia rheumatica? by Carvajal Alegria, Guillermo, Saraux, Alain, Devauchelle-Pensec, Valérie

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Hip Pain Associated with Acetabular Dysplasia in Patients with Suspected Axial Spondyloarthritis: DESIR Cohort Data by Guellec, Dewi, Prado, Guillaume, Miceli-Richard, Corinne, Carvajal-Alegria, Guillermo, Saraux, Alain

“…Objectives To determine whether acetabular dysplasia is associated with hip pain at physical examination among adults with recent-onset inflammatory back pain…”
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Correction of abnormal B-cell subset distribution by interleukin-6 receptor blockade in polymyalgia rheumatica by Carvajal Alegria, Guillermo, Devauchelle-Pensec, Valérie, Renaudineau, Yves, Saraux, Alain, Pers, Jacques-Olivier, Cornec, Divi

“…The aim was to study lymphocyte subsets and circulating cytokines at diagnosis of PMR and after tocilizumab monotherapy. Eighteen untreated patients with PMR…”
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Tocilizumab controls bone turnover in early polymyalgia rheumatica by Carvajal Alegria, Guillermo, Garrigues, Florent, Bettacchioli, Eleonore, Loeuille, Damien, Saraux, Alain, Cornec, Divi, Devauchelle-Pensec, Valérie, Renaudineau, Yves

“…•Bone turnover is impaired in polymyalgia rheumatica with an increased resorption.•Tocilizumab restores bone turnover in polymyalgia rheumatica.•Increase of…”
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Aortic involvement in giant cell arteritis by Carvajal Alegria, Guillermo, van Sleen, Yannick, Graver, Jacoba Carolien, Sandovici, Maria, Devauchelle-Pensec, Valérie, Brouwer, Elisabeth, Cornec, Divi

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Association of lumbosacral transitional vertebra and sacroiliitis in patients with inflammatory back pain suggesting axial spondyloarthritis by Carvajal Alegria, Guillermo, Voirin-Hertz, Marie, Garrigues, Florent, Herbette, Marion, Deloire, Lucile, Simon, Alexandre, Feydy, Antoine, Reijnierse, Monique, van der Heijde, Désirée, Marhadour, Thierry, Saraux, Alain

“…Abstract Objective Lumbosacral transitional vertebras (LSTVs) are common in the general population, but their potential impact on the sacroiliac joints is…”
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Healthy Patients Are Not the Best Controls for Microbiome-Based Clinical Studies: Example of Sjögren's Syndrome in a Systematic Review by Doaré, Elise, Héry-Arnaud, Geneviève, Devauchelle-Pensec, Valérie, Alegria, Guillermo Carvajal

“…It has been hypothesized that gut and oral dysbiosis may contribute to the development of primary Sjögren's syndrome (pSS). The aim of this systematic review…”
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