Search Results - "Aldersley, Michael F."

Mechanism of Montmorillonite Catalysis in the Formation of RNA Oligomers by Joshi, Prakash C, Aldersley, Michael F, Delano, John W, Ferris, James P

“…The montmorillonite clay-catalyzed reactions of nucleotides generate oligomers as long as 50-mers. The extent of catalysis depends on the magnitude of the…”
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MALDI Analysis of Oligonucleotides Directly from Montmorillonite by Zagorevskii, Dmitri V., Aldersley, Michael F., Ferris, James P.

“…Oligonucleotides synthesized on a montmorillonite catalyst were analyzed directly. By mixing the catalyst with a matrix (2,4,6-trihydroxyacetophenone or…”
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Clay catalyzed RNA synthesis under Martian conditions: Application for Mars return samples by Joshi, Prakash C., Dubey, Krishna, Aldersley, Michael F., Sausville, Meaghen

“…Catalysis by montmorillonites clay minerals is regarded as a feasible mechanism for the abiotic production and polymerization of key biomolecules on early…”
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Significance of Mineral Salts in Prebiotic RNA Synthesis Catalyzed by Montmorillonite by Joshi, Prakash C., Aldersley, Michael F.

“…The montmorillonite-catalyzed reactions of the 5′-phosphorimidazolide of adenosine used as a model generated RNA type oligomers. These reactions were found to…”
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The role of montmorillonite in its catalysis of RNA synthesis by Aldersley, Michael F., Joshi, Prakash C., Price, Jonathan D., Ferris, James P.

“…Montmorillonite catalyzes the oligomerization of activated nucleotides to form RNA. However, the mechanism of the montmorillonite catalysis, used as a model…”
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RNA dimer synthesis using montmorillonite as a catalyst: The role of surface layer charge by Aldersley, Michael F., Joshi, Prakash C.

“…The oligomerisation of activated nucleotides to form RNA is catalyzed by montmorillonite. However, the mechanism of this process and its use as a model for…”
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The Role of Fluoride in Montmorillonite-Catalyzed RNA Synthesis by Aldersley, Michael F., Joshi, Prakash C.

“…The montmorillonite-catalyzed reactions of the 5′-phosphorimidazolide of adenosine in the presence of fluoride were investigated to complete our study on the…”
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Progress in demonstrating total homochiral selection in montmorillonite-catalyzed RNA synthesis by Joshi, Prakash C., Aldersley, Michael F., Ferris, James P.

“…► Na+-montmorillonite catalyzed RNA synthesis from activated d,l-mononucleotides. ► About 63.5% of the dimers produced were homochiral. ► The homochirality…”
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Homochiral Selectivity in RNA Synthesis: Montmorillonite-catalyzed Quaternary Reactions of D, L-Purine with D, L- Pyrimidine Nucleotides by Joshi, Prakash C., Aldersley, Michael F., Ferris, James P.

“…Selective adsorption of D, L-ImpA with D, L-ImpU on the platelets of montmorillonite demonstrates an important reaction pathway for the origin of homochirality…”
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A Nucleotide Dimer Synthesis Without Protecting Groups Using Montmorillonite as Catalyst by Joshi, Prakash C., Aldersley, Michael F., Zagorevskii, Dmitri V., Ferris, James P.

“…A synthesis has been developed providing nucleotide dimers comprising natural or unnatural nucleoside residues. A ribonucleoside 5′-phosphorimidazolide is…”
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Signal Enhancement of Abiotically-Synthesized RNA Oligonucleotides and other Biopolymers using Unmodified Fused Silica in MALDI-MS by Cassidy, Lauren M., Dong, Yingying, Joshi, Prakash C., Aldersley, Michael F., Ferris, James P., McGown, Linda B.

“…Metal is the standard desorption platform for MALDI-MS but other surfaces have been shown to offer advantages for particular types of analytes or applications…”
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Progress in Studies on the RNA World by Joshi, Prakash C., Aldersley, Michael F., Price, Jonathan D., Zagorevski, Dmitri V., Ferris, James P.

“…The montmorillonite-catalyzed reactions of D, L-ImpA with D, L-ImpU generates RNA-like oligomers. The structures of the dimers to pentamers were investigated…”
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Supramolecular diaryliodonium salt-crown ether complexes as cationic photoinitiators by Crivello, James V., Aldersley, Michael F.

“…Diaryliodonium salts spontaneously form crystalline 1:1 supramolecular complexes at room temperature in good to excellent yields with 18‐crown‐6 ether and its…”
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The introduction of P–F bonds using aqueous fluoride ion and a water soluble carbodiimide: a convenient alternative synthesis of phosphorofluoridates and phosphonofluoridates by Aldersley, Michael F., Joshi, Prakash C., Ott, Elizabeth L., McCallum, Scott A., Kirby, Anthony J.

“…[Display omitted] •Ease of synthesis of P–F bonds from phosphates.•Ease of synthesis of P–F bonds from phosphonates.•Detailed NMR studies of the products…”
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Progress in demonstrating homochiral selection in prebiotic RNA synthesis by Joshi, Prakash C., Aldersley, Michael F., Ferris, James P.

“…The dual properties of RNA as an enzyme catalyst (ribozyme) and its ability to store genetic information suggest that early life could have been based on RNA…”
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The reaction of activated RNA species with aqueous fluoride ion: a convenient synthesis of nucleotide 5′-phosphorofluoridates and a note on the mechanism by Aldersley, Michael F., Joshi, Prakash C., Schwartz, Herbert M., Kirby, Anthony J.

“…The chemistry of 5′-phosphorimidazolides of ribonucleosides is extended to include their reaction with alkali metal fluorides in aqueous solution. High yields…”
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9 Prebiotic RNA synthesis: significance of mineral salts in montmorillonite-catalyzed reactions by Joshi, Prakash C., Aldersley, Michael F., Ferris, James P.

“…The dual properties of RNA as an enzyme catalyst and its ability to store genetic information suggest that early life was based on RNA, and DNA and protein…”
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10 The montmorillonite-catalyzed synthesis of RNA dimer by Aldersley, Michael F., Joshi, Prakash C., Ferris, James P.

“…A synthesis has been developed, providing nucleotide dimers comprising natural or unnatural nucleoside residues. A ribonucleoside 5′-phosphorimidazolide is…”
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Terahertz frequency optical constants of montmorillonite by Wilke, Ingrid, Ramanathan, Vidya, LaChance, Julienne, Aldersley, Michael F., Joshi, Prakash C., Ferris, James P.

“…The real and imaginary parts of the complex index of refraction of montmorillonite between 0.2 THz and 1.4 THz at room temperature are reported. The optical…”
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