Search Results - "Aldegheri, L"
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The discovery of (1R, 3R)-1-(3-chloro-5-fluorophenyl)-3-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline-6-carbonitrile, a potent and selective agonist of human transient receptor potential cation channel subfamily m member 5 (TRPM5) and evaluation of as a potential gastrointestinal prokinetic agent
Published in Bioorganic & medicinal chemistry (15-12-2022)“…[Display omitted] This publication details the discovery of a series of selective transient receptor potential cation channel subfamily M member 5 (TRPM5)…”
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Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS
Published in Neuroscience (01-01-2002)“…Group III metabotropic glutamate receptors (mGluRs) are selectively activated by L-2-amino-4-phosphonobutyrate ( L-AP4), which produces depression of synaptic…”
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Characterization of three diaminopyrimidines as potent and selective antagonists of P2X3 and P2X2/3 receptors with in vivo efficacy in a pain model
Published in British journal of pharmacology (01-07-2011)“…BACKGROUND AND PURPOSE P2X3 and P2X2/3 receptors are highly localized on the peripheral and central pathways of nociceptive signal transmission. The discovery…”
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Development of a functional reporter gene HTS assay for the identification of mGluR7 modulators
Published in Journal of biomolecular screening (01-08-2000)“…For the identification of modulators of the metabotropic glutamate receptor mGluR7, a functional cell-based high throughput screening (HTS) assay was…”
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Boron-interstitial clusters in crystalline silicon: stoichiometry and strain
Published in Materials science & engineering. B, Solid-state materials for advanced technology (15-12-2004)“…In this work, we have investigated the strain induced in a Si crystal by Boron-interstitial clusters (BICs). BICs were formed by Si implantation and subsequent…”
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Clinical, histological, and virological features of hepatitis C virus carriers with persistently normal or abnormal alanine transaminase levels
Published in Hepatology (Baltimore, Md.) (01-12-1997)“…This study was aimed to evaluate demographic, clinical, histological, and virological characteristics of 46 hepatitis C virus (HCV) carriers with persistently…”
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Pollen availability and abundance of predatory phytoseiid mites on natural and secondary hedgerows
Published in BioControl (Dordrecht, Netherlands) (01-08-2004)“…Mites occurring on a number ofnatural and secondary (i.e., planted) hedgerowslocated in north-eastern Italy were monitoredwith particular attention being paid…”
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Pharmacological properties of rat alpha 7 nicotinic receptors expressed in native and recombinant cell systems
Published in European journal of pharmacology (12-06-2002)“…The pharmacological properties of the rat alpha7 nicotinic acetylcholine receptor endogenously expressed in PC12 cells and recombinantly expressed in GH4C1…”
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The antidepressant fluoxetine blocks the human small conductance calcium-activated potassium channels SK1, SK2 and SK3
Published in Neuroscience letters (31-07-2003)“…The effects of fluoxetine (Prozac™) on the activity of human small-conductance calcium-activated potassium (SK) channels were investigated utilizing a…”
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Do symptomless HCV carriers spread infection to their relatives?
Published in The Lancet (British edition) (23-09-1995)Get more information
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Characterization of a new hemoprotein in the yeast Saccharomyces cerevisiae
Published in The Journal of biological chemistry (19-02-1999)“…The Saccharomyces cerevisiae gene YNL234w encodes a 426-amino acid-long protein that shares significant similarities with the globin family. Compared with…”
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Clinical, histological, and virological features of hepatitis C virus carriers with persistently normal or abnormal alanine transaminase levels
Published in Hepatology (Baltimore, Md.) (01-12-1997)“…This study was aimed to evaluate demographic, clinical, histological, and virological characteristics of 46 hepatitis C virus (HCV) carriers with persistently…”
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