Search Results - "Aldashev, A A"

The effects of hypoxia on the cells of the pulmonary vasculature by Pak, O, Aldashev, A, Welsh, D, Peacock, A

“…Pulmonary hypertension is associated with remodelling of pulmonary vessels. Chronic hypoxia is a common cause of pulmonary hypertension and pulmonary vascular…”
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A Criterion for the Uniqueness of the Solution of the Tricomi Problem for the Multidimensional Lavrent’ev–Bitsadze Equation by Aldashev, S. A.

“…An example of a mixed domain in which the solution of the Tricomi problem is trivial is given. A criterion for the uniqueness of the classical solution of this…”
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Effects of fasudil in patients with high-altitude pulmonary hypertension by Kojonazarov, B, Myrzaakhmatova, A, Sooronbaev, T, Ishizaki, T, Aldashev, A

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Phosphodiesterase type 5 and high altitude pulmonary hypertension by ALDASHEV, A. A, KOJONAZAROV, B. K, AMATOV, T. A, SOORONBAEV, T. M, MIRRAKHIMOV, M. M, MORRELL, N. W, WHARTON, J, WILKINS, M. R

“…This study explored phosphodiesterase type 5 (PDE5) inhibition as a strategy for treating high altitude pulmonary arterial hypertension (HAPH). 689 subjects…”
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Sildenafil inhibits hypoxia-induced pulmonary hypertension by ZHAO, L, MASON, N. A, MORRELL, N. W, KOJONAZAROV, B, SADYKOV, A, MARIPOV, A, MIRRAKHIMOV, M. M, ALDASHEV, A, WILKINS, M. R

“…This study investigated the effect of the phosphodiesterase 5 inhibitor sildenafil on the pulmonary vascular response to hypoxia in humans and mice. In a…”
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Smooth Muscle Cells Isolated From Discrete Compartments of the Mature Vascular Media Exhibit Unique Phenotypes and Distinct Growth Capabilities by Frid, M.G, Aldashev, A.A, Dempsey, E.C, Stenmark, K.R

“…Heterogeneity of smooth muscle cell (SMC) phenotype and function is rapidly emerging as an important concept. We have recently described that phenotypically…”
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Gene-to-gene interactions and the association of TP53, XRCC1, TNFα, HMMR, MDM2 and PALB2 with breast cancer in Kyrgyz females by Isakova, J. T., Vinnikov, D., Kipen, V. N., Talaibekova, E. T., Aldashev, A. A., Aldasheva, N. M., Makieva, K. B., Semetei kyzy, A., Bukuev, N. M., Tilekov, E. A., Shaimbetov, B. O., Kudaibergenova, I. O.

“…Background At present, little is known about the genetic background of breast cancer (BC) in Kyrgyz. Therefore, the aim of this study was to assess…”
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Association of the polymorphic marker Glu23Lys in the KCNJ11 gene with hypertension in Kyrgyz patients by Isakova, Zh T, Talaibekova, E T, Asambaeva, D A, Kerimkulova, A S, Lunegova, O S, Aldashev, A A

“…To study the association of the polymorphic marker Glu23Lys in the KCNJ11 with the development of hypertension in Kyrgyz patients. This case-control study…”
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Risk of type 2 diabetes mellitus in the Kyrgyz population in the presence of ADIPOQ (G276T), KCNJ11 (Glu23Lys), TCF7L2 (IVS3C>T) gene polymorphisms by Zh T Isakova, E T Talaibekova, D A Asambaeva, A S Kerimkulova, O S Lunegova, N M Aldasheva, A A Aldashev

“…Aim. To analyze the association of genotype combinations of the polymorphic markers G276T in the ADIPOQ gene, Glu23Lys in the KCNJ11 gene, and IVS3C>T in the…”
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Cerebral oxygenation in highlanders with and without high‐altitude pulmonary hypertension by Furian, M., Latshang, T. D., Aeschbacher, S. S., Ulrich, S., Sooronbaev, T., Mirrakhimov, E. M., Aldashev, A., Bloch, K. E.

“…New Findings What is the central question of this study? Cerebral hypoxia impairs cognitive function and exercise performance and may result in brain damage…”
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α1-A680T Variant in GUCY1A3 as a Candidate Conferring Protection From Pulmonary Hypertension Among Kyrgyz Highlanders by Wilkins, Martin R, Aldashev, Almaz A, Wharton, John, Rhodes, Christopher J, Vandrovcova, Jana, Kasperaviciute, Dalia, Bhosle, Shriram G, Mueller, Michael, Geschka, Sandra, Rison, Stuart, Kojonazarov, Baktybek, Morrell, Nicholas W, Neidhardt, Inga, Surmeli, Nur Basek, Aitman, Tim J, Stasch, Johannes-Peter, Behrends, Soenke, Marletta, Michael A

“…BACKGROUND—Human variation in susceptibility to hypoxia-induced pulmonary hypertension is well recognized. High-altitude residents who do not develop pulmonary…”
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A criterion for the unique solvability of the spectral Dirichlet problem for a class of multidimensional hyperbolic-parabolic equations by Serik A Aldashev

“…In the cylindrical domain of Euclidean space for one class of multidimensional hyperbolic parabolic equations the spectral Dirichlet problem with homogeneous…”
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Potential dual expansion of domesticated donkeys revealed by worldwide analysis on mitochondrial sequences by Ma, Xi-Yao, Ning, Tiao, Adeola, Adeniyi C, Li, Jie, Esmailizadeh, Ali, Lichoti, Jacqueline K, Agwanda, Bernard R, Isakova, Jainagul, Aldashev, Almaz A, Wu, Shi-Fang, Liu, He-Qun, Abdulloevich, Najmudinov Tojiddin, Afanasevna, Manilova Elena, Ibrohimovich, Khudoidodov Behruz, Adedokun, Rahamon Akinyele Moshood, Olaogun, Sunday Charles, Sanke, Oscar J, Mangbon, Godwin F, Chen, Xi, Yang, Wei-Kang, Wang, Zhe, Peng, Min-Sheng, Ommeh, Sheila C, Li, Yan, Zhang, Ya-Ping

“…Molecular studies on donkey mitochondrial sequences have clearly defined two distinct maternal lineages involved in domestication. However, domestication…”
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An association between TRP64ARG polymorphism of the B3 adrenoreceptor gene and some metabolic disturbances by Mirrakhimov, Aibek E, Kerimkulova, Alina S, Lunegova, Olga S, Moldokeeva, Cholpon B, Zalesskaya, Yulia V, Abilova, Samai S, Sovhozova, Nurmira A, Aldashev, Almaz A, Mirrakhimov, Erkin M

“…B3 adrenoreceptors (ADRB3) are abundant in adipose tissue and play the role in its metabolism and lipolysis. Some variants of the ADRB3 gene may predispose…”
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The Tricomi Problem for a Class of Multidimensional Hyperbolic-Elliptic Equations by Aldashev, S. A.

“…The solvability of the spatial Tricomi problem for a class of multidimensional hyperbolic-elliptic equations is proved…”
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Association of adiponectin gene G276T polymorphism with the development of metabolic syndrome in ethnic Kyrgyz patients by J T Isakova, O S Lunegova, E T Talaibekova, D A Asambaeva, A S Kerimkulova, A A Aldashev

“…Aim. To study the association of adiponectin gene G276Т (ADIPOQ) polymorphism with the development of metabolic syndrome (MS) in ethnic Kyrgyz patients…”
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Noninvasive and invasive evaluation of pulmonary arterial pressure in highlanders by Kojonazarov, B. K, Imanov, B. Z, Amatov, T. A, Mirrakhimov, M. M, Naeije, R, Wilkins, M. R, Aldashev, A. A

“…The purpose of the present study was to evaluate Doppler echocardiography for the detection of pulmonary hypertension in high-altitude inhabitants. In total,…”
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Bosentan reduces pulmonary artery pressure in high altitude residents by Kojonazarov, Baktybek, Isakova, Jainagul, Imanov, Bakytbek, Sovkhozova, Nurmira, Sooronbaev, Talantbek, Ishizaki, Takeshi, Aldashev, Almaz A

“…Endothelin-1 (ET-1) plays a critical role in the regulation of pulmonary vascular tone. The aim of this study was to investigate the role of ET-1 in the…”
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Well-posedness of the Dirichlet and Poincaré problems for one class of hyperbolic equations in a multidimensional domain by Serik A Aldashev

“…In early works the author studied the Dirichlet and Poincaré problems for multidimensional hyperbolic equations, which shows the well-posedness of these…”
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Polymorphism in the TRP8 gene in Kyrgyz population: putative association with highland adaptation by V. N. Babenko, Ж. Т. Isakova, E. T. Talaibekova, D. A. Asambaeva, V. F. Kobzev, T. A. Potapova, M. I. Voevoda, A. A. Aldashev

“…The human TRPM8 gene encodes a receptor mediating cold sensitivity, and this fact points to its putative role in cold adaptation. The structural variability of…”
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