Search Results - "Aldahdooh, Jehad"
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SynergyFinder Plus: Toward Better Interpretation and Annotation of Drug Combination Screening Datasets
Published in Genomics, proteomics & bioinformatics (01-06-2022)“…Combinatorial therapies have been recently proposed to improve the efficacy of anticancer treatment. The SynergyFinder R package is a software used to analyze…”
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DrugComb: an integrative cancer drug combination data portal
Published in Nucleic acids research (02-07-2019)“…Drug combination therapy has the potential to enhance efficacy, reduce dose-dependent toxicity and prevent the emergence of drug resistance. However, discovery…”
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RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection
Published in Nature communications (02-06-2021)“…Bacterial processes necessary for adaption to stressful host environments are potential targets for new antimicrobials. Here, we report large-scale…”
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Using BERT to identify drug-target interactions from whole PubMed
Published in BMC bioinformatics (21-06-2022)“…Abstract Background Drug-target interactions (DTIs) are critical for drug repurposing and elucidation of drug mechanisms, and are manually curated by large…”
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DrugRepo: a novel approach to repurposing drugs based on chemical and genomic features
Published in Scientific reports (07-12-2022)“…The drug development process consumes 9–12 years and approximately one billion US dollars in costs. Due to the high finances and time costs required by the…”
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Can We Assume the Gene Expression Profile as a Proxy for Signaling Network Activity?
Published in Biomolecules (Basel, Switzerland) (03-06-2020)“…Studying relationships among gene products by expression profile analysis is a common approach in systems biology. Many studies have generalized the outcomes…”
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DrugComb update: a more comprehensive drug sensitivity data repository and analysis portal
Published in Nucleic acids research (02-07-2021)“…Abstract Combinatorial therapies that target multiple pathways have shown great promises for treating complex diseases. DrugComb (https://drugcomb.org/) is a…”
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Mining drug-target interactions from biomedical literature using chemical and gene descriptions-based ensemble transformer model
Published in Bioinformatics advances (2024)“…Drug-target interactions (DTIs) play a pivotal role in drug discovery, as it aims to identify potential drug targets and elucidate their mechanism of action…”
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Minimal information for chemosensitivity assays (MICHA): a next-generation pipeline to enable the FAIRification of drug screening experiments
Published in Briefings in bioinformatics (17-01-2022)“…Abstract Chemosensitivity assays are commonly used for preclinical drug discovery and clinical trial optimization. However, data from independent assays are…”
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R-BERT-CNN: Drug-target interactions extraction from biomedical literature
Published 31-10-2021“…Proceedings of the BioCreative VII Workshop. (2021) 102-106 In this research, we present our work participation for the DrugProt task of BioCreative VII…”
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Traffic Congestion Prevention Using Ant Colony Optimization
Published in 2023 8th International Engineering Conference on Renewable Energy & Sustainability (ieCRES) (08-05-2023)“…Managing traffic congestion is crucial for improving mobility, reducing fuel consumption, and mitigating environmental impacts in urban areas. To address this…”
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