Search Results - "Aldaba, Eneko"

In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma by Pérez-Salvia, Montserrat, Aldaba, Eneko, Vara, Yosu, Fabre, Myriam, Ferrer, Cristina, Masdeu, Carme, Zubia, Aizpea, Sebastian, Eider San, Otaegui, Dorleta, Llinàs-Arias, Pere, Rosselló-Tortella, Margalida, Berdasco, Maria, Moutinho, Catia, Setien, Fernando, Villanueva, Alberto, González-Barca, Eva, Muncunill, Josep, Navarro, José-Tomás, Piris, Miguel A, Cossio, Fernando P, Esteller, Manel

“…Cancer origin and development is associated not only with genetic alterations, but also with the disturbance of epigenetic profiles.1 In this regard, the…”
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Synthesis of a hexasaccharide fragment of the capsular polysaccharide of Streptococcus pneumoniae type 3 by Lefeber, Dirk J, Arévalo, Eneko Aldaba, Kamerling, Johannis P, Vliegenthart, Johannes FG

“…In the framework of the development of a new generation of neoglycoconjugate vaccines against Streptococcus pneumoniae, the synthesis is described of a…”
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Stereocontrolled formation of substituted imidazolidines in the reaction between N-metalated azomethine ylides and isocyanates by Erkizia, Edurne, Aldaba, Eneko, Vara, Yosu, Arrieta, Ana, Gornitzka, Heinz, Cossío, Fernando P.

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Abstract 4725: Efficacy of a new small-molecule inhibitor of histone deacetylase 6 (HDAC6) in preclinical models of B-cell lymphoma and acute myeloid leukemia by Villanueva, Lorea, Perez-Salvia, Montserrat, Aldaba, Eneko, Vara, Yosu, Fabre, Myriam, Ferrer, Cristina, Masdeu, Carme, Zubia, Aizpea, Sebastian, Eider San, Otaegui, Dorleta, Llinàs-Arias, Pere, Rosselló-Tortella, Margalida, Berdasco, María, Setien, Fernando, Moutinho, Catia, Villanueva, Alberto, González-Barca, Eva, Muncunill, Josep, Navarro, José Tomás, Piris, Miguel Ángel, Cossio, Fernando, Esteller, Manel

“…Histone deacetylase 6 (HDAC6) is a protein modifier that is an increasingly attractive pharmacological target. Interestingly, the observation that the HDAC6…”
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Efficacy of a New Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) in Preclinical Models of B-Cell Lymphoma and Acute Myeloid Leukemia by Perez-Salvia, Montserrat, Eneko, Aldaba, Yosu, Vara, Myriam, Fabre, Cristina, Ferrer, Carme, Masdeu, Aizpea, Zubia, Eider, San Sebastian, Dorleta, Otaegui, Pere, Llinàs-Arias, Margalida, Rosselló-Tortella, Maria, Berdasco, Fernando, Setien, Catia, Moutinho, Alberto, Villanueva, González-Barca, Eva, Muncunill, Josep, Navarro, Jose Tomas, Piris, Miguel Angel, Fernando, Cossio, Esteller, Manel

“…Histone deacetylase 6 (HDAC6) is a protein modifier that is an increasingly attractive pharmacological target. Interestingly, the observation that the HDAC6…”
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In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma by Pérez Salvia, Montserrat, Aldaba, Eneko, Vara, Yosu, Fabre, Myriam, Ferrer, Cristina, Masdeu, Carme, Zubia, Aizpea, San Sebastian, Eider, Otaegui, Dorleta, Llinàs-Arias, Pere, Rosselló-Tortella, Margalida, Berdasco, María, Moutinho, Cátia, Setién, Fernando, Villanueva Garatachea, Alberto, González Barca, Eva, Muncunill, Josep, Navarro, José-Tomás, Piris, Miguel A, Cossio, Fernando P, Esteller, Manel

“…Cancer origin and development is associated not only with genetic alterations, but also with the disturbance of epigenetic profiles.1 In this regard, the…”
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Application of Stereocontrolled Stepwise [3+2] Cycloadditions to the Preparation of Inhibitors of α4β1-Integrin-Mediated Hepatic Melanoma Metastasis by Zubia, Aizpea, Mendoza, Lorea, Vivanco, Silvia, Aldaba, Eneko, Carrascal, Teresa, Lecea, Begoña, Arrieta, Ana, Zimmerman, Tahl, Vidal-Vanaclocha, Fernando, Cossío, Fernando P.

“…Inhibitors of the interaction between protein VLA‐4 and its natural ligand VCAM‐1 have been designed, even though the structure of the protein remains…”
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Trans-Stereoselectivity in the Reaction between Homophthalic Anhydride and Imines by Vara, Yosu, Bello, Tamara, Aldaba, Eneko, Arrieta, Ana, Pizarro, José L, Arriortua, María I, Lopez, Xabier, Cossío, Fernando P

“…The reaction between homophthalic anhydride and imines in the presence of TiCl4 and diisopropyl ethyl amine is trans-selective. Under these conditions, the…”
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Development and validation of a LC-MS assay for the quantification of ikh12 a novel anti-tumor candidate in rat plasma and tissues and its application in a pharmacokinetic study by Otaegui, Dorleta, Masdeu, Carme, Aldaba, Eneko, Vara, Yosu, Zubia, Aizpea, San Sebastian, Eider, Alcalá, Maria, Villafruela, Sergio, Cossío, Fernando P., Rodriguez-Gascón, Alicia

“…IKH12 is a novel histone deacetylase 6 selective inhibitor. A rapid and sensitive liquid chromatography tandem mass spectrometry method was developed and…”
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Application of stereocontrolled stepwise [3+2] cycloadditions to the preparation of inhibitors of alpha4beta1-integrin-mediated hepatic melanoma metastasis by Zubia, Aizpea, Mendoza, Lorea, Vivanco, Silvia, Aldaba, Eneko, Carrascal, Teresa, Lecea, Begoña, Arrieta, Ana, Zimmerman, Tahl, Vidal-Vanaclocha, Fernando, Cossio, Fernando P

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Application of Stereocontrolled Stepwise [3+2] Cycloadditions to the Preparation of Inhibitors of α 4 β 1 ‐Integrin‐Mediated Hepatic Melanoma Metastasis by Zubia, Aizpea, Mendoza, Lorea, Vivanco, Silvia, Aldaba, Eneko, Carrascal, Teresa, Lecea, Begoña, Arrieta, Ana, Zimmerman, Tahl, Vidal‐Vanaclocha, Fernando, Cossío, Fernando P.

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Application of Stereocontrolled Stepwise [3+2] Cycloadditions to the Preparation of Inhibitors of α 4 β 1 ‐Integrin‐Mediated Hepatic Melanoma Metastasis by Zubia, Aizpea, Mendoza, Lorea, Vivanco, Silvia, Aldaba, Eneko, Carrascal, Teresa, Lecea, Begoña, Arrieta, Ana, Zimmerman, Tahl, Vidal‐Vanaclocha, Fernando, Cossío, Fernando P.

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Application of Stereocontrolled Stepwise [3+2] Cycloadditions to the Preparation of Inhibitors of α4β1-Integrin-Mediated Hepatic Melanoma Metastasis by Zubia, Aizpea, Mendoza, Lorea, Vivanco, Silvia, Aldaba, Eneko, Carrascal, Teresa, Lecea, Begoña, Arrieta, Ana, Zimmerman, Tahl, Vidal-Vanaclocha, Fernando, Cossío, Fernando P.

“…Inhibitoren der Wechselwirkung zwischen dem Protein VLA‐4 und seinem natürlichen Liganden VCAM‐1 wurden entwickelt, obwohl die Struktur des Proteins unbekannt…”
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