Search Results - "Alcudia, Javier F."

Lysyl oxidase and endothelial dysfunction: mechanisms of lysyl oxidase down-regulation by pro-inflammatory cytokines by Alcudia, Javier F, Martinez-Gonzalez, Jose, Guadall, Anna, Gonzalez-Diez, Maria, Badimon, Lina, Rodriguez, Cristina

“…Lysyl oxidase (LOX) plays a pivotal role in extracellular matrix (ECM) maturation. Furthermore, novel biological functions has been ascribed to LOX, among them…”
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A compact synthetic pathway rewires cancer signaling to therapeutic effector release by Chung, Hokyung K, Zou, Xinzhi, Bajar, Bryce T, Brand, Veronica R, Huo, Yunwen, Alcudia, Javier F, Ferrell, Jr, James E, Lin, Michael Z

“…An important goal in synthetic biology is to engineer biochemical pathways to address unsolved biomedical problems. One long-standing problem in molecular…”
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Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases by Rodríguez, Cristina, Martínez-González, José, Raposo, Berta, Alcudia, Javier F., Guadall, Anna, Badimon, Lina

“…Lysyl oxidase (LOX) plays a crucial role in the maintenance of extracellular matrix stability and could participate in vascular remodelling associated with…”
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Corrigendum: Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin by Wu, Colleen, Rankin, Erinn B, Castellini, Laura, Alcudia, Javier F, LaGory, Edward L, Andersen, Rebecca, Rhodes, Steven D, Wilson, Tremika L S, Mohammad, Khalid S, Castillo, Alesha B, Guise, Theresa A, Schipani, Ernestina, Giaccia, Amato J

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Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors by Rodríguez, Cristina, Alcudia, Javier F., Martínez-González, José, Guadall, Anna, Raposo, Berta, Sánchez-Gómez, Sonia, Badimon, Lina

“…Aims Statins are lipid-lowering drugs widely used in the management of vascular diseases. Clinical and experimental evidence suggest that statins improve…”
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Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells by Guadall, Anna, Orriols, Mar, Alcudia, Javier F, Cachofeiro, Victoria, Martinez-Gonzalez, Jose, Rodriguez, Cristina

“…The adaptive response of endothelial cells to hypoxia involves a substantial remodeling of extracellular matrix (ECM). In endothelial cells hypoxia…”
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Engineered Ovarian Cancer Cell Lines for Validation of CAR T Cell Function by Repellin, Claire E., Ganesan, Priya, Alcudia, Javier F., Lakshmireddy, Haritha K. Duggireddy, Patel, Puja, Beviglia, Lucia, Javitz, Harold S., Sambucetti, Lidia, Bhatnagar, Parijat

“…A set of genetically engineered isogenic cell lines is developed to express either folate receptor alpha or mesothelin, and a control cell line negative for…”
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Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin by Wu, Colleen, Rankin, Erinn B, Castellini, Laura, Alcudia, Javier F, Fernandez-Alcudia, Javier, LaGory, Edward L, Andersen, Rebecca, Rhodes, Steven D, Wilson, Tremika L S, Mohammad, Khalid S, Castillo, Alesha B, Guise, Theresa A, Schipani, Ernestina, Giaccia, Amato J

“…The bone microenvironment is composed of niches that house cells across variable oxygen tensions. However, the contribution of oxygen gradients in regulating…”
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