Search Results - "Albuquerque, Dulcineia M."

Angiogenesis-Related Genes in Endothelial Progenitor Cells May Be Involved in Sickle Cell Stroke by Ito, Mirta T, da Silva Costa, Sueli M, Baptista, Letícia C, Carvalho-Siqueira, Gabriela Q, Albuquerque, Dulcinéia M, Rios, Vinicius M, Ospina-Prieto, Stephanie, Saez, Roberta C, Vieira, Karla P, Cendes, Fernando, Ozelo, Margareth C, Saad, Sara Teresinha O, Costa, Fernando F, Melo, Mônica B

“…Background The clinical aspects of sickle cell anemia (SCA) are heterogeneous, and different patients may present significantly different clinical evolutions…”
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Influence of UGT1A1 promoter polymorphism, α-thalassemia and βs haplotype in bilirubin levels and cholelithiasis in a large sickle cell anemia cohort by Batista, Jéssica V. G. F., Arcanjo, Gabriela S., Batista, Thais H. C., Sobreira, Marcondes J., Santana, Rodrigo M., Domingos, Igor F., Hatzlhofer, Betânia L., Falcão, Diego A., Pereira-Martins, Diego A., Oliveira, Jéssica M., Araujo, Amanda S., Laranjeira, Luana P. M., Medeiros, Fernanda S., Albuquerque, Flávia P., Albuquerque, Dulcinéia M., Santos, Magnun N., Hazin, Manuela F., dos Anjos, Ana C., Costa, Fernando F., Araujo, Aderson S., Lucena-Araujo, Antonio R., Bezerra, Marcos A.

“…Hyperbilirubinemia in patients with sickle cell anemia (SCA) as a result of enhanced erythrocyte destruction, lead to cholelithiasis development in a subset of…”
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Rare α0-thalassemia deletions detected by MLPA in five unrelated Brazilian patients by Mota, Natália O, Kimura, Elza M, Ferreira, Roberta D, Pedroso, Gisele A, Albuquerque, Dulcinéia M, Ribeiro, Daniela M, Santos, Magnun N N, Bittar, Cristina M, Costa, Fernando F, Sonati, Maria de Fatima

“…Alpha-thalassemias are among the most common genetic diseases in the world. They are characterized by hypochromic and microcytic anemia and great clinical…”
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Surveillance of active human cytomegalovirus infection in hematopoietic stem cell transplantation (HLA sibling identical donor): search for optimal cutoff value by real-time PCR by Peres, Renata M B, Costa, Cláudia R C, Andrade, Paula D, Bonon, Sandra H A, Albuquerque, Dulcinéia M, de Oliveira, Cristiane, Vigorito, Afonso C, Aranha, Francisco J P, de Souza, Cármino A, Costa, Sandra C B

“…Human cytomegalovirus (CMV) infection still causes significant morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT)…”
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Deferasirox associated with liver failure and death in a sickle cell anemia patient homozygous for the −1774delG polymorphism in the Abcc2 gene by Braga, Caroline C. B., Benites, Bruno Deltreggia, Albuquerque, Dulcineia M., Alvarez, Marisa C., Seva‐Pereira, Tiago, Duarte, Bruno K. L., Costa, Fernando F., Gilli, Simone C. O., Saad, Sara T. O.

“…Key Clinical Message This manuscript describes the case of a patient with sickle cell anemia who died of fulminant hepatitis after therapy with the iron…”
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MTHFR polymorphic variant C677T is associated to vascular complications in sickle-cell disease by Hatzlhofer, Betânia L D, Bezerra, Marcos André C, Santos, Magnun N N, Albuquerque, Dulcinéia M, Freitas, Elizabete M, Costa, Fernando F, Araújo, Aderson S, Muniz, Maria Tereza C

“…Vaso-occlusion is a determinant for most signs and symptoms of sickle-cell anemia (SCA). The mechanisms involved in the pathogenesis of vascular complications…”
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Molecular characteristics and chromatin texture features in acute promyelocytic leukemia by De Mello, Mariana R B, Albuquerque, Dulcineia M, Pereira-Cunha, Fernanda Gonçalves, Albanez, Krizzia B, Pagnano, Katia B B, Costa, Fernando F, Metze, Konradin, Lorand-Metze, Irene

“…Acute promyelocytic leukemia is a cytogenetically well defined entity. Nevertheless, some features observed at diagnosis are related to a worse outcome of the…”
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Influence of alpha thalassemia on clinical and laboratory parameters among nigerian children with sickle cell anemia by Olatunya, Oladele S., Albuquerque, Dulcineia M., Adekile, Adekunle, Costa, Fernando F.

“…Background There is paucity of data on the influence of alpha thalassemia on the clinical and laboratory parameters among Nigerian sickle cell anemia (SCA)…”
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Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs by Fornari, Thais A, Lanaro, Carolina, Albuquerque, Dulcinéia M, Ferreira, Regiane, Costa, Fernando F

“…Hereditary persistence of fetal hemoglobin deletion type-2 (HPFH-2) and Sicilian-δβ-thalassemia are conditions described as large deletions of the human β-like…”
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High levels of proinflammatory cytokines IL-6 and IL-8 are associated with a poor clinical outcome in sickle cell anemia by Domingos, Igor F., Pereira-Martins, Diego A., Sobreira, Marcondes J. V. C., Oliveira, Romulo T. D., Alagbe, Adekunle E., Lanaro, Carolina, Albuquerque, Dulcineia M., Blotta, Maria H. S. L., Araujo, Aderson S., Costa, Fernando F., Lucena-Araujo, Antonio R., Sonati, Maria F., Bezerra, Marcos A. C., Santos, Magnun N. N.

“…Sickle cell anemia (SCA) pathophysiology is characterized by the activation of sickle red blood cells, reticulocytes, leukocytes, platelets, and endothelial…”
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Reduced rate of sickle‐related complications in Brazilian patients carrying HbF‐promoting alleles at the BCL11A and HMIP‐2 loci by Leonardo, Flávia C., Brugnerotto, Ana F., Domingos, Igor F., Fertrin, Kleber Y., Albuquerque, Dulcinéia M., Bezerra, Marcos A. C., Araújo, Aderson S., Saad, Sara T. O., Costa, Fernando F., Menzel, Stephan, Conran, Nicola, Thein, Swee Lay

“…Summary The presence of high levels of fetal haemoglobin (HbF) provides well‐validated clinical benefits to patients with sickle cell anaemia (SCA)…”
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Two new unstable haemoglobins leading to chronic haemolytic anaemia: Hb Caruaru [β122 (GH5) Phe→Ser], a probable case of germ line mutation, and Hb Olinda [β22 (B4) ‐ 25 (B7)], a deletion of a 12 base‐pair sequence by Bezerra, Marcos A. C., Albuquerque, Dulcinéia M., Santos, Magnun N. N., Kimura, Elza M., Jorge, Susan E. D. C., Oliveira, Denise M., Domingues, Betânia L. T. B., Peres, Jaqueline C., Araújo, Aderson S., Costa, Fernando F., Sonati, Maria F.

“…We describe here two new unstable β‐globin variants, Hb Caruaru and Hb Olinda, found in northeastern Brazil, both associated with chronic haemolytic anaemia…”
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An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis by Hollanda, Luciana M, Lima, Carmen S P, Costa, Fernando F, Vassallo, José, Saad, Sara T O, Cunha, Anderson F, Joazeiro, Paulo P, Ozelo, Margareth C, Albuquerque, Dulcinéia M

“…Acquired somatic mutations in exon 2 of the hematopoietic transcription factor GATA-1 have been found in individuals with Down syndrome with both transient…”
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Thalassemia major phenotype caused by HB Zürich‐Albisrieden [α2 59(E8) Gly > Arg (HBA2:C.178G > C)] in a Brazilian child by Pedroso, Gisele A., Kimura, Elza M., Santos, Magnun N.N., Albuquerque, Dulcinéia M., Malimpensa, Danaê, Jorge, Susan E., Verissimo, Monica P.A., Costa, Fernando F., Sonati, Maria F.

“…Hemoglobin (Hb) Zürich‐Albisrieden (ZA) [α2 59(E8) Gly > Arg; HBA2:c.178G > C] is a rare and highly unstable α‐chain variant. A few simple and compound…”
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Association of Nitric Oxide Synthase and Matrix Metalloprotease Single Nucleotide Polymorphisms with Preeclampsia and Its Complications by Leonardo, Daniela P, Albuquerque, Dulcinéia M, Lanaro, Carolina, Baptista, Letícia C, Cecatti, José G, Surita, Fernanda G, Parpinelli, Mary A, Costa, Fernando F, Franco-Penteado, Carla F, Fertrin, Kleber Y, Costa, Maria Laura

“…Preeclampsia is one of the leading causes of maternal and neonatal morbidity and mortality in the world, but its appearance is still unpredictable and its…”
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Abnormal expression of inflammatory genes in placentas of women with sickle cell anemia and sickle hemoglobin C disease by Baptista, Letícia C., Costa, Maria Laura, Ferreira, Regiane, Albuquerque, Dulcinéia M., Lanaro, Carolina, Fertrin, Kleber Y., Surita, Fernanda G., Parpinelli, Mary A., Costa, Fernando F., Melo, Mônica Barbosa de

“…Sickle cell disease (SCD) is a complex disease that is characterized by the polymerization of deoxyhemoglobin S, altered red blood cell membrane biology,…”
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Cytomegalovirus (CMV) genotype in allogeneic hematopoietic stem cell transplantation by Dieamant, Débora C, Bonon, Sandra H A, Peres, Renata M B, Costa, Claudia R C, Albuquerque, Dúlcinéia M, Miranda, Eliana C M, Aranha, Francisco J P, Oliveira-Duarte, Gislaine, Fernandes, Virginio C A, De Souza, Carmino A, Costa, Sandra C B, Vigorito, Afonso C

“…Based on sequence variation in the UL55 gene that encodes glycoprotein B (gB), human cytomegalovirus (CMV) can be classified into four gB genotypes. Previous…”
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Reduced plasma angiotensin II levels are reversed by hydroxyurea treatment in mice with sickle cell disease by dos Santos, Alisson F., Almeida, Camila B., Brugnerotto, Ana F., Roversi, Fernanda M., Pallis, Flávia R., Franco-Penteado, Carla F., Lanaro, Carolina, Albuquerque, Dulcinéia M., Leonardo, Flávia C., Costa, Fernando F., Conran, Nicola

“…Sickle cell disease (SCD) pathogenesis leads to recurrent vaso-occlusive and hemolytic processes, causing numerous clinical complications including renal…”
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Hb S-São Paulo: A new sickling hemoglobin with stable polymers and decreased oxygen affinity by Jorge, Susan E.D.C., Petruk, Ariel A., Kimura, Elza M., Oliveira, Denise M., Caire, Lucas, Suemasu, Cintia N., Silveira, Paulo A.A., Albuquerque, Dulcineia M., Costa, Fernando F., Skaf, Munir S., Martínez, Leandro, Sonati, Maria de Fatima

“…► A new human β-globin variant was found: Hb S-São Paulo [HBB:c.20A>T p.Glu6Val; c.196A>G p.Lys65Glu]. ► The double-mutant caused clinical features of sickle…”
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Coinheritance of Hb Bristol-Alesha [β67(E11)Val→Met; HBB: c.202G>A] and the α212 Patchwork Allele in a Brazilian Child with Severe Congenital Hemolytic Anemia by Pedroso, Gisele A., Kimura, Elza M., Santos, Magnun N. N., Albuquerque, Dulcinéia M., Ferruzzi, Jucilane L. H., Jorge, Susan E., Costa, Fernando F., Saad, Sara T. O., Sonati, Maria F.

“…Hb Bristol-Alesha [HBB: c.202G>A; β 67 Val>Met] is a rare structural variant of hemoglobin (Hb) resulting from a GTG>ATG substitution at codon 67 of the…”
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