Search Results - "Alblewi, Fawzia F"
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Synthesis and Characterization of a New Class of Chromene-Azo Sulfonamide Hybrids as Promising Anticancer Candidates with the Exploration of Their EGFR, hCAII, and MMP-2 Inhibitors Based on Molecular Docking Assays
Published in International journal of molecular sciences (01-12-2023)“…In this study, novel selective antitumor compounds were synthesized based on their fundamental pharmacophoric prerequisites associated with EGFR inhibitors. A…”
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Design of New Benzo[h]chromene Derivatives: Antitumor Activities and Structure-Activity Relationships of the 2,3-Positions and Fused Rings at the 2,3-Positions
Published in Molecules (Basel, Switzerland) (18-03-2017)“…A series of novel 4 -benzo[ ]chromenes , - , , ; 7 -benzo[ ]chromeno[2,3- ]pyrimidines - , , and 14 -benzo[ ]chromeno[3,2- ][1,2,4]triazolo[1,5- ]pyrimidine…”
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Design and Synthesis of Novel Heterocyclic-Based 4H-benzo[h]chromene Moieties: Targeting Antitumor Caspase 3/7 Activities and Cell Cycle Analysis
Published in Molecules (Basel, Switzerland) (18-03-2019)“…Novel fused chromenes (4,7–11) and pyrimidines (12–16) were designed, synthesized, and evaluated for their mammary gland breast cancer (MCF-7), human colon…”
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Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene
Published in Bioorganic chemistry (01-06-2019)“…[Display omitted] •Design of novel fused chromene and pyrimidine derivatives as promising anticancer agents.•The cytotoxic activity of the new molecules was…”
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A proficient microwave synthesis with structure elucidation and the exploitation of the biological behavior of the newly halogenated 3-amino-1H-benzo[f]chromene molecules, targeting dual inhibition of topoisomerase II and microtubules
Published in Bioorganic chemistry (01-01-2020)“…[Display omitted] •β-enamionitriles, linked 8-bromo-1H-benzo[f]chromene moieties were synthesized as potential anticancer agents.•The cytotoxic activity was…”
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Thermal studies and mass loss inhibition for some new mixed amino acid metal complexes with their applications
Published in Journal of thermal analysis and calorimetry (01-07-2016)“…A thermal gravimetric analysis was studied for the new metal mixed-ligand complexes of copper(II), nickel(II), cobalt(II), and zinc(II) metals formed with…”
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Synthesis and Characterization of a New Class of Chromene-Azo Sulfonamide Hybrids as Promising Anticancer Candidates with the Exploration of Their EGFR, Ih/ICAII, and MMP-2 Inhibitors Based on Molecular Docking Assays
Published in International journal of molecular sciences (01-11-2023)“…In this study, novel selective antitumor compounds were synthesized based on their fundamental pharmacophoric prerequisites associated with EGFR inhibitors. A…”
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Journal Article -
8
Synthesis and Characterization of a New Class of Chromene-Azo Sulfonamide Hybrids as Promising Anticancer Candidates with the Exploration of Their EGFR, h CAII, and MMP-2 Inhibitors Based on Molecular Docking Assays
Published in International journal of molecular sciences (24-11-2023)“…In this study, novel selective antitumor compounds were synthesized based on their fundamental pharmacophoric prerequisites associated with EGFR inhibitors. A…”
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9
Design and Synthesis of Novel Heterocyclic-Based 4 H -benzo[ h ]chromene Moieties: Targeting Antitumor Caspase 3/7 Activities and Cell Cycle Analysis
Published in Molecules (Basel, Switzerland) (18-03-2019)“…Novel fused chromenes ( , ⁻ ) and pyrimidines ( ⁻ ) were designed, synthesized, and evaluated for their mammary gland breast cancer (MCF-7), human colon cancer…”
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