Search Results - "Albin, R.L"

Impaired contrast sensitivity is associated with more severe cognitive impairment in Parkinson disease by Ridder, A, Müller, M.L.T.M, Kotagal, V, Frey, K.A, Albin, R.L, Bohnen, N.I

“…Abstract Objectives Dopaminergic degeneration affects both nigrostriatal projection neurons and retinal amacrine cells in Parkinson disease (PD). Parkinsonian…”
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The p75 neurotrophin receptor augments survival signaling in the striatum of pre-symptomatic Q175WT/HD mice by Wehner, A.B, Milen, A.A, Albin, R.L, Pierchala, B.A

“…Highlights • Increased survival signaling in pre-symptomatic Q175 mice abolished by p75 deletion. • Q175WT/HD ;p75−/− mice have decreased expression of XIAP,…”
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Diabetes, Gray Matter Loss, and Cognition in the Setting of Parkinson Disease by Petrou, M, Davatzikos, C, Hsieh, M, Foerster, B.R, Albin, R.L, Kotagal, V, Müller, M.L, Koeppe, R.A, Herman, W.H, Frey, K.A, Bohnen, N.I

“…Rationale and Objectives Parkinson disease (PD) is a progressive neurodegenerative disorder affecting motor and cognitive functions. Prior studies showed that…”
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Distribution and kinetics of GABAB binding sites in rat central nervous system: a quantitative autoradiographic study by Chu, D C, Albin, R L, Young, A B, Penney, J B

“…[3H]GABA quantitative autoradiography was used to examine the binding kinetics and regional distribution of GABAB receptors in rat brain. The regional…”
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Effects of Periventricular White Matter Lesions on PD Cognitive Deficits are Mediated by Limbic Cholinergic Deficits in PD by Carli, G., Brown, T., Roytman, S., Biddix, A., Vangel, R., Kanel, P., Albin, R.L., Bohnen, N.I.

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Localization of AMPA-selective excitatory amino acid receptor subunits in identified populations of striatal neurons by Tallaksen-Greene, S J, Albin, R L

“…Two-color immunofluorescence histochemistry and immunohistochemistry in combination with retrograde tract-tracing techniques were used to examine the…”
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Cardiac sympathetic denervation and anxiety in Parkinson disease by Carli, G., Kanel, P., Michalakis, F., Roytman, S., Bohnen, J.L.B., Wigstrom, T.P., Scott, P., Albin, R.L., Wong, K.K., Raffel, D., Bohnen, N.I.

“…Anxiety in Parkinson disease (PD) negatively impacts quality of life. While research predominantly focuses on central nervous system changes, some evidence…”
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Predicting Progression from Normal to MCI and from MCI to AD Using Clinical Variables in the National Alzheimer’s Coordinating Center Uniform Data Set Version 3: Application of Machine Learning Models and a Probability Calculator by Pang, Y., Kukull, W., Sano, M., Albin, R. L., Shen, C., Zhou, J., Dodge, Hiroko H.

“…Clinical trials are increasingly focused on pre-manifest and early Alzheimer’s disease (AD). Accurately predicting clinical progressions from normal to MCI or…”
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The p75 neurotrophin receptor augments survival signaling in the striatum of pre-symptomatic Q175(WT/HD) mice by Wehner, A B, Milen, A M, Albin, R L, Pierchala, B A

“…Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder characterized by a constellation of motor, cognitive, and psychiatric features…”
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Body Composition, Falls, and Freezing of Gait in Parkinson's Disease: Gender-Specific Effects by Pongmala, C, Stonsaovapak, C, van Emde Boas, M, Bhanderi, H, Luker, A, Michalakis, F, Kanel, P, Albin, R L, Haus, J M, Bohnen, N I

“…Postural instability and gait difficulties (PIGD) are a significant cause of mobility loss and lower quality of life in Parkinson's disease (PD). When PD…”
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Differential loss of striatal projection systems in Huntington’s disease: a quantitative immunohistochemical study by Deng, Y.P, Albin, R.L, Penney, J.B, Young, A.B, Anderson, K.D, Reiner, A

“…Prior studies suggest differences exist among striatal projection neuron types in their vulnerability to Huntington’s disease (HD). In the present study, we…”
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Decreased striatal dopaminergic innervation in REM sleep behavior disorder by ALBIN, R. L, KOEPPE, R. A, CHERVIN, R. D, CONSENS, F. B, WERNETTE, K, FREY, K. A, ALDRICH, M. S

“…REM sleep behavior disorder (RBD) is a possible herald of neurodegenerative disorders with parkinsonism. The authors determined the density of striatal…”
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Increased ventral striatal monoaminergic innervation in Tourette syndrome by Albin, R L, Koeppe, R A, Bohnen, N I, Nichols, T E, Meyer, P, Wernette, K, Minoshima, S, Kilbourn, M R, Frey, K A

“…Excessive striatal dopaminergic innervation is suggested to underlie Tourette syndrome (TS). Prior imaging and postmortem studies yield conflicting data. The…”
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Fetal striatal transplantation in Huntington's disease: time for a pause; the need to look at the rationale for fetal striatal transplantation by Albin, R.L

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Sham surgery controls are mitigated trolleys by Albin, R L

“…Debate continues about the ethics of sham surgery controls. The most powerful argument for sham surgery controls is that rigorous experiments are needed to…”
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Neuronal intranuclear inclusions and neuropil aggregates in Hdh CAG(150) knockin mice by Tallaksen-Greene, S.J., Crouse, A.B., Hunter, J.M., Detloff, P.J., Albin, R.L.

“…We studied the development of neuronal intranuclear inclusions (NIIs), neuropil aggregates (NAs), and expression of expanded repeat polyglutamine protein in…”
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Decreased striatal monoaminergic terminals in Huntington disease by BOHNEN, N. I, KOEPPE, R. A, MEYER, P, FICARO, E, WERNETTE, K, KILBOURN, M. R, KUHL, D. E, FREY, K. A, ALBIN, R. L

“…To evaluate the integrity of the dorsal striatal dopaminergic innervation in rigid and choreic Huntington disease (HD). Some patients with HD have an…”
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Excitatory amino acid binding sites in the basal ganglia of the rat: a quantitative autoradiographic study by Albin, R L, Makowiec, R L, Hollingsworth, Z R, Dure, 4th, L S, Penney, J B, Young, A B

“…Quantitative receptor autoradiography was used to determine the distribution of excitatory amino acid binding sites in the basal ganglia of rat brain…”
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Differential Loss of Striatal Projection Neurons in Huntington Disease by Reiner, Anton, Albin, Roger L., Anderson, Keith D., D'Amato, Constance J., Penney, John B., Young, Anne B.

“…Huntington disease (HD) is characterized by the loss of striatal projection neurons, which constitute the vast majority of striatal neurons. To determine…”
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Striatal presynaptic monoaminergic vesicles are not increased in Tourette's syndrome by Meyer, P, Bohnen, N I, Minoshima, S, Koeppe, R A, Wernette, K, Kilbourn, M R, Kuhl, D E, Frey, K A, Albin, R L

“…Abnormal function of striatal dopaminergic synapses is suggested to underlie Tourette's syndrome (TS). To determine dorsal striatal dopaminergic innervation in…”
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