Search Results - "Albieri, Benedetta"
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LTX-315 and adoptive cell therapy using tumor-infiltrating lymphocytes generate tumor specific T cells in patients with metastatic soft tissue sarcoma
Published in Oncoimmunology (31-12-2024)“…LTX-315 is an oncolytic peptide that elicits both local and systemic immune responses upon intratumoral injection. In the present pilot trial, we treated…”
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First in man study: Bcl-Xl_42-CAF ® 09b vaccines in patients with locally advanced prostate cancer
Published in Frontiers in immunology (14-03-2023)“…The B-cell lymphoma-extra-large (Bcl-XL) protein plays an important role in cancer cells' resistance to apoptosis. Pre-clinical studies have shown that…”
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Dose escalation study of a personalized peptide-based neoantigen vaccine (EVX-01) in patients with metastatic melanoma
Published in Journal for immunotherapy of cancer (23-05-2024)“…BackgroundNeoantigens can serve as targets for T cell-mediated antitumor immunity via personalized neopeptide vaccines. Interim data from our clinical study…”
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918 Functional heterogeneity of CD4+ tumor-infiltrating lymphocytes
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundImmunotherapy has demonstrated impressive results in numerous metastatic solid tumors. However, while most studies have focused on immune responses…”
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LTX-315 and adoptive cell therapy using tumor-infiltrating lymphocytes in patients with metastatic soft tissue sarcoma
Published in Journal of clinical oncology (01-06-2022)“…11567 Background: Adoptive cell transfer (ACT) with tumor-infiltrating lymphocytes (TILs) is a potent treatment that can induce complete and durable tumor…”
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Uncoupling CD4+ TIL-mediated tumor killing from JAK-signaling in melanoma
Published in Clinical cancer research (02-10-2023)“…Impaired MHCI-presentation and insensitivity to immune effector molecules are common features of immune checkpoint blockade(ICB)-resistant tumors and can be…”
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Final results: Dose escalation study of a personalized peptide-based neoantigen vaccine in patients with metastatic melanoma
Published in Journal of clinical oncology (01-06-2023)“…9551 Background: Despite the advances made with CPIs such as aPD-1/aPD-L1, aCTL4 and aLAG-3 there still is a significant unmet medical need for patients with…”
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