Search Results - "Albi, Elisa"
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NOTCH1 Aberrations in Chronic Lymphocytic Leukemia
Published in Frontiers in oncology (27-06-2018)“…Chronic lymphocytic leukemia (CLL) is an incurable B-cell neoplasm characterized by highly variable clinical outcomes. In recent years, genomic and molecular…”
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P1489: HIGH DOSE IRON IMPAIRS MALIGNANT B‐CELL VIABILITY AND IMPROVES IMMUNE ANTITUMOR FUNCTIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA
Published in HemaSphere (08-08-2023)Get full text
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NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells
Published in Frontiers in oncology (20-04-2018)“…To investigate chronic lymphocytic leukemia (CLL)-initiating cells, we assessed mutation/expression in hematopoietic stem cells (HSCs). In mutated CLL, we…”
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P646: VENETOCLAX RETREATMENT AFTER MRD‐GUIDED VENETOCLAX +/‐ IBRUTINIB: THE IMPROVE STUDY COHORT
Published in HemaSphere (08-08-2023)Get full text
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Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin
Published in Molecular cytogenetics (16-01-2018)“…Collision tumors are rare entities that consist of two histologically distinct tumor types arising in the same anatomic site. An association between chronic…”
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Are we finally getting personal? Moving towards a personalized approach in chronic lymphocytic leukemia
Published in Seminars in cancer biology (01-09-2022)“…With its heterogeneous biological features and clinical course, chronic lymphocytic leukemia (CLL), the most frequent adult leukemia in the Western world, is a…”
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Chronic Lymphocytic Leukemia (CLL) Patients Quality of Life (QoL): A Cross-Sectional Analysis of the Italian Experience in the Choice Study during the First Wave of the COVID-19 Pandemic
Published in Blood (23-11-2021)“…Introduction Although plenty of data exists on efficacy and safety of CLL drugs, their impact on patients' Health-Related Quality of Life (HRQoL) is largely…”
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Minimal residual disease–driven treatment intensification with sequential addition of ibrutinib to venetoclax in R/R CLL
Published in Blood (01-12-2022)“…•A sequential MRD-guided addition of ibrutinib to venetoclax led to uMRD in 33 (87%) of 38 patients with relapsed/refractory CLL.•This MRD-driven strategy…”
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Outcomes of Venetoclax Retreatment after MRD-Guided Venetoclax +/- Ibrutinib: Results of the Improve Study
Published in Blood (02-11-2023)“…Data from small cohorts of patients (pts) with chronic lymphocytic leukemia (CLL) relapsing after venetoclax-based fixed-duration regimens suggest that…”
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CLL-461 Humoral Response to COVID-19 Vaccine: A Challenge in CLL
Published in Clinical lymphoma, myeloma and leukemia (01-10-2022)“…Chronic lymphocytic leukaemia (CLL) is associated with some degree of immune dysfunction as a result of the disease itself and/or treatment. COVID-19 has a…”
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Decreased NOTCH1 Activation Correlates with Response to Ibrutinib in Chronic Lymphocytic Leukemia
Published in Clinical cancer research (15-12-2019)“…Ibrutinib, a Bruton tyrosine kinase inhibitor (BTKi), has improved the outcomes of chronic lymphocytic leukemia (CLL), but primary resistance or relapse are…”
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Poster: CLL-461 Humoral Response to COVID-19 Vaccine: A Challenge in CLL
Published in Clinical lymphoma, myeloma and leukemia (01-10-2022)Get full text
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An Observational Study on Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Treated with Venetoclax-Based Regimens Outside Clinical Trials in Italy (GIMEMA CLL1920)
Published in Blood (23-11-2021)“…Venetoclax is the first BCL-2 inhibitor approved for the treatment of patients with chronic lymphocytic leukemia (CLL) alone or in combination with anti-CD20…”
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Patients' preferences for chronic lymphocytic leukemia treatment: The CHOICE study
Published in Hematological oncology (01-01-2024)“…Chronic lymphocytic leukemia (CLL) therapies differ in efficacy, side effects, route, frequency, and duration of administration. We assessed patient…”
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Minimal Residual Disease-Driven Treatment Intensification By Sequential Addition of Ibrutinib to Venetoclax in Relapsed/Refractory Chronic Lymphocytic Leukemia: Results of the Monotherapy and Combination Phases of the Improve Study
Published in Blood (05-11-2020)“…The treatment of chronic lymphocytic leukemia (CLL) has been radically changed in the last years thanks to the targeted therapies, including kinase (i.e…”
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NOTCH1 Aberrant Activation Is a Common Nonmutational Early Event in Chronic Lymphocytic Leukemia Hematopoietic Stem-Cells
Published in Blood (08-12-2017)“…Chronic lymphocytic leukemia (CLL) is a B cell disorder characterized by constitutive NOTCH1 activation. NOTCH1 mutations are recurrently associated with CLL…”
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Ibrutinib Treatment of a Patient with Relapsing Chronic Lymphocytic Leukemia and Sustained Remission of Richter Syndrome
Published in Tumori (01-11-2017)“…Purpose Richter syndrome (RS) is a rare event in chronic lymphocytic leukemia (CLL) that is influenced by biological factors and prior CLL treatments…”
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Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin
Published in Molecular cytogenetics (01-01-2018)“…BACKGROUNDCollision tumors are rare entities that consist of two histologically distinct tumor types arising in the same anatomic site. An association between…”
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