Search Results - "Albert Y. Xue"
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Systems Approach to Integrative Biology: An Overview of Statistical Methods to Elucidate Association and Architecture
Published in Integrative and comparative biology (01-07-2014)“…An organismâs ability to maintain a desired physiological response relies extensively on how cellular and molecular signaling networks interpret and react to…”
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Journal Article -
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DUETT quantitatively identifies known and novel events in nascent RNA structural dynamics from chemical probing data
Published in Bioinformatics (Oxford, England) (15-12-2019)“…RNA molecules can undergo complex structural dynamics, especially during transcription, which influence their biological functions. Recently developed…”
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Journal Article -
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Machine Learning on Signal-to-Noise Ratios Improves Peptide Array Design in SAMDI Mass Spectrometry
Published in Analytical chemistry (Washington) (05-09-2017)“…Emerging peptide array technologies are able to profile molecular activities within cell lysates. However, the structural diversity of peptides leads to…”
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Journal Article -
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Inferring causal molecular networks: empirical assessment through a community-based effort
Published in Nature methods (01-04-2016)“…The HPN-DREAM community challenge assessed the ability of computational methods to infer causal molecular networks, focusing specifically on the task of…”
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Journal Article -
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Finding the Needle in the Haystack: Applying Data Science to Address Biological Questions
Published 01-01-2018“…Biology is entering the exciting world of big data. Modern high-throughput experimental techniques often produce large datasets that aim to capture complex…”
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Dissertation