Search Results - "Albert, P R"
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Persistent post-stroke depression in mice following unilateral medial prefrontal cortical stroke
Published in Translational psychiatry (02-08-2016)“…Post-stroke depression (PSD) is a common outcome following stroke that is associated with poor recovery. To develop a preclinical model of PSD, we targeted a…”
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Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress
Published in Neuroscience (10-11-2009)“…Abstract Chronic stress is known to affect brain areas involved in learning and emotional responses. These changes, thought to be related to the development of…”
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A functional alternative splicing mutation in human tryptophan hydroxylase-2
Published in Molecular psychiatry (01-12-2011)“…The brain serotonergic system has an essential role in the physiological functions of the central nervous system and dysregulation of serotonin (5-HT)…”
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Brain derived neurotrophic factor, cardiopulmonary fitness and cognition in patients with coronary artery disease
Published in Brain, behavior, and immunity (01-08-2011)“…Highlight ► Links between serum BDNF, fitness and psychomotor processing speed in subjects with coronary artery disease evince a role of BDNF in the cognitive…”
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Mood disturbances in Parkinson's disease: From prodromal origins to application of animal models
Published in Neurobiology of disease (01-06-2023)“…Parkinson's disease (PD) is a complex illness with a constellation of environmental insults and genetic vulnerabilities being implicated. Strikingly, many…”
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A critical protein kinase C phosphorylation site on the 5-HT1A receptor controlling coupling to N-type calcium channels
Published in The Journal of physiology (01-01-2002)“…The importance of specific protein kinase C (PKC) sites for modulation of the inhibitory coupling of 5-HT 1A receptors to N-type Ca 2+ channels was examined…”
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Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine1A receptor gene
Published in The Journal of biological chemistry (05-04-1990)“…G protein-coupled receptors comprise a family of genes that share significant sequence similarity. We have screened a rat genomic library under low stringency…”
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The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription
Published in Translational psychiatry (01-03-2016)“…The G/C single-nucleotide polymorphism in the serotonin 1a receptor promoter, rs6295, has previously been linked with depression, suicide and antidepressant…”
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The 5-HT1A receptor: Signaling, desensitization, and gene transcription
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-1996)“…The hypothesis that antianxiety or antidepressant agents (e.g., 5-HT1A agonists, 5-HT uptake blockers) exert their clinical actions via enhancement of…”
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10
Cell-specific signaling of the 5-HT1A receptor. Modulation by protein kinases C and A
Published in The Journal of biological chemistry (15-12-1991)“…Heterologous expression of the rat 5-HT1A receptor in stably transfected GH4C1 rat pituitary cells (clone GH4ZD10) and mouse Ltk- fibroblast cells (clone…”
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Coupling of a cloned rat dopamine-D2 receptor to inhibition of adenylyl cyclase and prolactin secretion
Published in The Journal of biological chemistry (05-02-1990)“…We have previously described a cDNA which encodes a binding site with the pharmacology of the D2-dopamine receptor (Bunzow, J. R., VanTol, H. H. M., Grandy, D…”
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12
COMT polymorphism modulates the resting‐state EEG alpha oscillatory response to acute nicotine in male non‐smokers
Published in Genes, brain and behavior (01-07-2015)“…Performance improvements in cognitive tasks requiring executive functions are evident with nicotinic acetylcholine receptor (nAChR) agonists, and activation of…”
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Inhibitory control of prolactin and Pit-1 gene promoters by dopamine. Dual signaling pathways required for D2 receptor-regulated expression of the prolactin gene
Published in The Journal of biological chemistry (05-12-1991)“…Transcription of the prolactin gene is suppressed by dopaminergic activation of D2 receptors in pituitary lactotrophs. The mechanism of signal transduction at…”
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TATA‐Driven Transcriptional Initiation and Regulation of the Rat Serotonin 5‐HT1A Receptor Gene
Published in Journal of neurochemistry (01-06-1999)“…: The transcriptional initiation and regulation of the rat serotonin 5‐HT1A receptor gene were characterized. By three types of analyses, a single…”
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Endogenous serotonin-2A and -2C receptors in Balb/c-3T3 cells revealed in serotonin-free medium: Desensitization and down-regulation by serotonin
Published in Biochemical pharmacology (15-11-1998)“…We studied the endogenous expression of the serotonin-2A (5-hydroxytryptamine 2A, 5-HT 2A) 5-HT 2C, and a splice-variant of the 5-HT 2C receptor in murine…”
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A Novel cdc2‐Related Protein Kinase Expressed in the Nervous System
Published in Journal of neurochemistry (01-07-1997)“…: We report the cloning and characterization of a cDNA encoding a cdc2‐related protein kinase, named PFTAIRE, that is expressed primarily in the postnatal and…”
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17
Cloning and differentiation-induced expression of a murine serotonin1A receptor in a septal cell line
Published in The Journal of neuroscience (01-12-1993)“…A neuronal cell model endogenously expressing the 5-HT1A receptor, in which to study the function and regulation of this gene, has yet to be identified. We…”
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18
Ionomycin acts as an ionophore to release TRH-regulated Ca2+ stores from GH4C1 cells
Published in The American journal of physiology (01-12-1986)“…In the GH4C1 strain of rat pituitary cells, ionomycin, a divalent cation ionophore, induces a rapid and transient spike in cytosolic free Ca2+ concentrations…”
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Heterodimerization of Mineralocorticoid and Glucocorticoid Receptors at a Novel Negative Response Element of the 5-HT1A Receptor Gene
Published in The Journal of biological chemistry (27-04-2001)“…Negative regulation of neuronal serotonin (5-HT1A) receptor levels by glucocorticoids in vivo may contribute to depression. Both types I (mineralocorticoid)…”
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APAF1 Is a Key Transcriptional Target for p53 in the Regulation of Neuronal Cell Death
Published in The Journal of cell biology (15-10-2001)“…p53 is a transcriptional activator which has been implicated as a key regulator of neuronal cell death after acute injury. We have shown previously that…”
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