Search Results - "Albert, Matthew L"

Biology and pathogenesis of chikungunya virus by Schwartz, Olivier, Albert, Matthew L

“…Key Points Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that provokes arthralgia and, potentially, severe complications in humans. A…”
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Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations by Quach, Hélène, Rotival, Maxime, Pothlichet, Julien, Loh, Yong-Hwee Eddie, Dannemann, Michael, Zidane, Nora, Laval, Guillaume, Patin, Etienne, Harmant, Christine, Lopez, Marie, Deschamps, Matthieu, Naffakh, Nadia, Duffy, Darragh, Coen, Anja, Leroux-Roels, Geert, Clément, Frederic, Boland, Anne, Deleuze, Jean-François, Kelso, Janet, Albert, Matthew L., Quintana-Murci, Lluis

“…Humans differ in the outcome that follows exposure to life-threatening pathogens, yet the extent of population differences in immune responses and their…”
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Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia by Crotta, Stefania, Davidson, Sophia, Mahlakoiv, Tanel, Desmet, Christophe J, Buckwalter, Matthew R, Albert, Matthew L, Staeheli, Peter, Wack, Andreas

“…Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to…”
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Dying to Replicate: The Orchestration of the Viral Life Cycle, Cell Death Pathways, and Immunity by Yatim, Nader, Albert, Matthew L.

“…Manipulation of cell death pathways has been identified as a common feature of host-microbe interactions. We examine two examples: influenza A as a…”
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Transposable element expression in tumors is associated with immune infiltration and increased antigenicity by Kong, Yu, Rose, Christopher M., Cass, Ashley A., Williams, Alexander G., Darwish, Martine, Lianoglou, Steve, Haverty, Peter M., Tong, Ann-Jay, Blanchette, Craig, Albert, Matthew L., Mellman, Ira, Bourgon, Richard, Greally, John, Jhunjhunwala, Suchit, Chen-Harris, Haiyin

“…Profound global loss of DNA methylation is a hallmark of many cancers. One potential consequence of this is the reactivation of transposable elements (TEs)…”
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Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth by Hollande, Clémence, Boussier, Jeremy, Ziai, James, Nozawa, Tamaki, Bondet, Vincent, Phung, Wilson, Lu, Binfeng, Duffy, Darragh, Paradis, Valerie, Mallet, Vincent, Eberl, Gérard, Sandoval, Wendy, Schartner, Jill M., Pol, Stanislas, Barreira da Silva, Rosa, Albert, Matthew L.

“…Post-translational modification of chemokines mediated by the dipeptidyl peptidase DPP4 (CD26) has been shown to negatively regulate lymphocyte trafficking,…”
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Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis by Tait, Stephen W.G., Oberst, Andrew, Quarato, Giovanni, Milasta, Sandra, Haller, Martina, Wang, Ruoning, Karvela, Maria, Ichim, Gabriel, Yatim, Nader, Albert, Matthew L., Kidd, Grahame, Wakefield, Randall, Frase, Sharon, Krautwald, Stefan, Linkermann, Andreas, Green, Douglas R.

“…Programmed necrosis (or necroptosis) is a form of cell death triggered by the activation of receptor interacting protein kinase-3 (RIPK3). Several reports have…”
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Visualizing the innate and adaptive immune responses underlying allograft rejection by two-photon microscopy by Celli, Susanna, Albert, Matthew L, Bousso, Philippe

“…Whether graft rejection occurs by direct or indirect presentation of antigen is still controversial. However, using a mouse ear skin allograft model and a…”
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Functional Analysis via Standardized Whole-Blood Stimulation Systems Defines the Boundaries of a Healthy Immune Response to Complex Stimuli by Duffy, Darragh, Rouilly, Vincent, Libri, Valentina, Hasan, Milena, Beitz, Benoit, David, Mikael, Urrutia, Alejandra, Bisiaux, Aurélie, LaBrie, Samuel T., Dubois, Annick, Boneca, Ivo G., Delval, Cécile, Thomas, Stéphanie, Rogge, Lars, Schmolz, Manfred, Quintana-Murci, Lluis, Albert, Matthew L., Abel, Laurent, Alcover, Andres, Bousso, Philippe, Cumano, Ana, Daëron, Marc, Delval, Cécile, Demangel, Caroline, Deriano, Ludovic, Di Santo, James, Dromer, Françoise, Eberl, Gérard, Enninga, Jost, Freitas, Antonio, Gomperts-Boneca, Ivo, Hercberg, Serge, Lantz, Olivier, Leclerc, Claude, Mouquet, Hugo, Pellegrini, Sandra, Pol, Stanislas, Rogge, Lars, Sakuntabhai, Anavaj, Schwartz, Olivier, Schwikowski, Benno, Shorte, Spencer, Soumelis, Vassili, Tangy, Frédéric, Tartour, Eric, Toubert, Antoine, Ungeheuer, Marie-Noëlle, Quintana-Murci, Lluis, Albert, Matthew L.

“…Standardization of immunophenotyping procedures has become a high priority. We have developed a suite of whole-blood, syringe-based assay systems that can be…”
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Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration by Lim, Yoong Wearn, Chen-Harris, Haiyin, Mayba, Oleg, Lianoglou, Steve, Wuster, Arthur, Bhangale, Tushar, Khan, Zia, Mariathasan, Sanjeev, Daemen, Anneleen, Reeder, Jens, Haverty, Peter M., Forrest, William F., Brauer, Matthew, Mellman, Ira, Albert, Matthew L.

“…Cancer immunotherapy has emerged as an effective therapy in a variety of cancers. However, a key challenge in the field is that only a subset of patients who…”
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Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity by Alloatti, Andrés, Rookhuizen, Derek C, Joannas, Leonel, Carpier, Jean-Marie, Iborra, Salvador, Magalhaes, Joao G, Yatim, Nader, Kozik, Patrycja, Sancho, David, Albert, Matthew L, Amigorena, Sebastian

“…CD8 T cells mediate antigen-specific immune responses that can induce rejection of solid tumors. In this process, dendritic cells (DCs) are thought to take up…”
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Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer by Khan, Zia, Di Nucci, Flavia, Kwan, Antonia, Hammer, Christian, Mariathasan, Sanjeev, Rouilly, Vincent, Carroll, Jonathan, Fontes, Magnus, Acosta, Sergio Ley, Guardino, Ellie, Chen-Harris, Haiyin, Bhangale, Tushar, Mellman, Ira, Rosenberg, Jonathan, Powles, Thomas, Hunkapiller, Julie, Chandler, G. Scott, Albert, Matthew L.

“…PD-1 and PD-L1 act to restrict T cell responses in cancer and contribute to self-tolerance. Consistent with this role, PD-1 checkpoint inhibitors have been…”
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Mechanisms of immune-related adverse events associated with immune checkpoint blockade: using germline genetics to develop a personalized approach by Khan, Zia, Hammer, Christian, Guardino, Ellie, Chandler, G Scott, Albert, Matthew L

“…Personalized care of cancer patients undergoing treatment with immune checkpoint inhibitors will require approaches that can predict their susceptibility to…”
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A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals by Scepanovic, Petar, Hodel, Flavia, Mondot, Stanislas, Partula, Valentin, Byrd, Allyson, Hammer, Christian, Alanio, Cécile, Bergstedt, Jacob, Patin, Etienne, Touvier, Mathilde, Lantz, Olivier, Albert, Matthew L, Duffy, Darragh, Quintana-Murci, Lluis, Fellay, Jacques

“…The gut microbiome is an important determinant of human health. Its composition has been shown to be influenced by multiple environmental factors and likely by…”
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Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade by Khan, Zia, Hammer, Christian, Carroll, Jonathan, Di Nucci, Flavia, Acosta, Sergio Ley, Maiya, Vidya, Bhangale, Tushar, Hunkapiller, Julie, Mellman, Ira, Albert, Matthew L., McCarthy, Mark I., Chandler, G. Scott

“…Activation of systemic immune responses using PD-1 checkpoint inhibitors is an essential approach to cancer therapy. Yet, the extent of benefit relative to…”
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RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity by Orozco, Susana L., Daniels, Brian P., Yatim, Nader, Messmer, Michelle N., Quarato, Giovanni, Chen-Harris, Haiyin, Cullen, Sean P., Snyder, Annelise G., Ralli-Jain, Pooja, Frase, Sharon, Tait, Stephen W.G., Green, Douglas R., Albert, Matthew L., Oberst, Andrew

“…Necroptosis is a form of programmed cell death that is defined by activation of the kinase RIPK3 and subsequent cell membrane permeabilization by the effector…”
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Chikungunya virus-induced autophagy delays caspase-dependent cell death by Joubert, Pierre-Emmanuel, Werneke, Scott W, de la Calle, Claire, Guivel-Benhassine, Florence, Giodini, Alessandra, Peduto, Lucie, Levine, Beth, Schwartz, Olivier, Lenschow, Deborah J, Albert, Matthew L

“…Autophagy is an important survival pathway and can participate in the host response to infection. Studying Chikungunya virus (CHIKV), the causative agent of a…”
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Bacillus Calmette-Guérin Strain Differences Have an Impact on Clinical Outcome in Bladder Cancer Immunotherapy by Rentsch, Cyrill A, Birkhäuser, Frédéric D, Biot, Claire, Gsponer, Joël R, Bisiaux, Aurélie, Wetterauer, Christian, Lagranderie, Micheline, Marchal, Gilles, Orgeur, Mickael, Bouchier, Christiane, Bachmann, Alexander, Ingersoll, Molly A, Brosch, Roland, Albert, Matthew L, Thalmann, George N

“…Abstract Background Whether the commonly used bacillus Calmette-Guérin (BCG) strains Connaught and Tice confer different treatment responses in…”
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Macrophages Subvert Adaptive Immunity to Urinary Tract Infection by Mora-Bau, Gabriela, Platt, Andrew M, van Rooijen, Nico, Randolph, Gwendalyn J, Albert, Matthew L, Ingersoll, Molly A

“…Urinary tract infection (UTI) is one of the most common bacterial infections with frequent recurrence being a major medical challenge. Development of effective…”
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Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation by Nalle, Sam C, Barreira da Silva, Rosa, Zhang, Hua, Decker, Markus, Chalouni, Cecile, Xu, Min, Posthuma, George, de Mazière, Ann, Klumperman, Judith, Baz Morelli, Adriana, Fleire, Sebastian J, Verkman, Alan S, Trombetta, E Sergio, Albert, Matthew L, Mellman, Ira

“…Antigen cross presentation, whereby exogenous antigens are presented by MHC class I molecules to CD8+ T cells, is essential for generating adaptive immunity to…”
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