Search Results - "Albers, Michael F"
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Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway
Published in PLoS pathogens (01-12-2015)“…Small molecule signaling promotes the communication between bacteria as well as between bacteria and eukaryotes. The opportunistic pathogenic bacterium…”
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2
Amino Acid Building Blocks for Efficient Fmoc Solid-Phase Synthesis of Peptides Adenylylated at Serine or Threonine
Published in Organic letters (18-11-2011)“…The first straightforward building block based (non-interassembly) synthesis of peptides containing adenylylated serine and threonine residues is described…”
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Efficient Synthesis and Applications of Peptides containing Adenylylated Tyrosine Residues
Published in Angewandte Chemie International Edition (19-09-2011)“…The enzyme DrrA of the human pathogen Legionella pneumophila adenylylates specifically a tyrosine of the GTPase Rab1. An efficient synthesis route using Fmoc…”
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Covalent Protein Labeling by Enzymatic Phosphocholination
Published in Angewandte Chemie International Edition (24-08-2015)“…We present a new protein labeling method based on the covalent enzymatic phosphocholination of a specific octapeptide amino acid sequence in intact proteins…”
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5
Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture
Published in Nature chemistry (01-08-2020)“…Various pathogenic bacteria use post-translational modifications to manipulate the central components of host cell functions. Many of the enzymes released by…”
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The [alpha]-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signalling and gene expression of Legionella pneumophila
Published in Molecular microbiology (01-02-2016)“…Summary The causative agent of Legionnaires' disease, Legionella pneumophila, employs the autoinducer compound LAI-1 (3-hydroxypentadecane-4-one) for cell-cell…”
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The α‐hydroxyketone LAI‐1 regulates motility, Lqs‐dependent phosphorylation signalling and gene expression of Legionella pneumophila
Published in Molecular microbiology (01-02-2016)“…Summary The causative agent of Legionnaires' disease, Legionella pneumophila, employs the autoinducer compound LAI‐1 (3‐hydroxypentadecane‐4‐one) for cell–cell…”
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Amino Acid Building Blocks for Fmoc Solid-Phase Synthesis of Peptides Phosphocholinated at Serine, Threonine, and Tyrosine
Published in Journal of organic chemistry (15-03-2013)“…Phosphocholination of eukaryotic host cell proteins has recently been identified as a novel post-translational modification important for bacterial…”
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Photoactivated Colibactin Probes Induce Cellular DNA Damage
Published in Angewandte Chemie International Edition (28-01-2019)“…Colibactin is a small molecule produced by certain bacterial species of the human microbiota that harbour the pks genomic island. Pks+ bacteria induce a…”
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Exploring Adenylylation and Phosphocholination as Post-Translational Modifications
Published in Chembiochem : a European journal of chemical biology (03-01-2014)“…Editing the translations: Adenylylation and phosphocholination have recently been found as important post‐translational modifications used by pathogenic…”
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Photoactivated Colibactin Probes Induce Cellular DNA Damage
Published in Angewandte Chemie (28-01-2019)“…Colibactin is a small molecule produced by certain bacterial species of the human microbiota that harbour the pks genomic island. Pks+ bacteria induce a…”
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Kovalente Proteinmarkierung durch enzymatische Phosphocholinierung
Published in Angewandte Chemie (24-08-2015)“…Wir präsentieren eine neue Methode zur Proteinmarkierung, die auf der kovalenten enzymatischen Phosphocholinierung einer spezifischen Octapeptidsequenz…”
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Effiziente Synthese und Anwendung von Peptiden mit adenylylierten Tyrosinresten
Published in Angewandte Chemie (19-09-2011)Get full text
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Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway: e1005307
Published in PLoS pathogens (01-12-2015)“…Small molecule signaling promotes the communication between bacteria as well as between bacteria and eukaryotes. The opportunistic pathogenic bacterium…”
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Journal Article -
15
Kovalente Proteinmarkierung durch enzymatische Phosphocholinierung
Published in Angewandte Chemie (24-08-2015)“…Wir präsentieren eine neue Methode zur Proteinmarkierung, die auf der kovalenten enzymatischen Phosphocholinierung einer spezifischen Octapeptidsequenz…”
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Effiziente Synthese und Anwendung von Peptiden mit adenylylierten Tyrosinresten
Published in Angewandte Chemie (19-09-2011)“…Das Enzym DrrA des human‐pathogenen Bakteriums Legionella pneumophila adenylyliert spezifisch einen Tyrosinrest der GTPase Rab1. Eine effiziente Syntheseroute…”
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